A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF

by Daniel J. Lightwood, Rebecca J. Munro, John Porter, David McMillan, Bruce Carrington, Alison Turner, Anthony Scott-Tucker, Elizabeth S. Hickford, Antje Schmidt, David Fox, Alison Maloney, Tom Ceska, Tim Bourne, James O’Connell, Alastair D. G. Lawson
Published 2021-01-01

WNT3A‐loaded exosomes enable cartilage repair

by Bethan L. Thomas, Suzanne E. Eldridge, Babak Nosrati, Mario Alvarez, Anne‐Sophie Thorup, Giovanna Nalesso, Sara Caxaria, Aida Barawi, James G. Nicholson, Mauro Perretti, Carles Gaston‐Massuet, Costantino Pitzalis, Alison Maloney, Adrian Moore, Ray Jupp, Francesco Dell'Accio
Published 2021-05-01

Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer

by James O’Connell, John Porter, Boris Kroeplien, Tim Norman, Stephen Rapecki, Rachel Davis, David McMillan, Tracy Arakaki, Alex Burgin, David Fox III, Tom Ceska, Fabien Lecomte, Alison Maloney, Alex Vugler, Bruce Carrington, Benjamin P Cossins, Tim Bourne, Alastair Lawson
Published 2019-12-01