Divergent Roles for TRAIL in Lung Diseases

by Adam T. Braithwaite, Helen M. Marriott, Allan Lawrie
Published 2018-07-01

Circulating Protein Biomarkers in Systemic Sclerosis Related Pulmonary Arterial Hypertension: A Review of Published Data

by Peter M. Hickey, Peter M. Hickey, Allan Lawrie, Robin Condliffe
Published 2018-06-01

TRAIL Deficient Mice Are Protected from Sugen/Hypoxia Induced Pulmonary Arterial Hypertension

by Sarah H. Dawson, Nadine D. Arnold, Josephine A. Pickworth, Sheila E. Francis, Allan Lawrie
Published 2014-07-01

Editorial: Pulmonary Hypertension: Mechanisms and Management, History and Future

by A. A. Roger Thompson, A. A. Roger Thompson, Martin R. Wilkins, Jim M. Wild, Jim M. Wild, Jim M. Wild, David G. Kiely, David G. Kiely, David G. Kiely, Allan Lawrie, Allan Lawrie
Published 2020-04-01

No evidence for cardiac dysfunction in Kif6 mutant mice.

by Abdul Hameed, Ellen Bennett, Barbara Ciani, Loes P C Hoebers, Roy Milner, Allan Lawrie, Sheila E Francis, Andrew J Grierson
Published 2013-01-01

High levels of healthcare utilization prior to diagnosis in idiopathic pulmonary arterial hypertension support the feasibility of an early diagnosis algorithm: the SPHInX project

by Rito Bergemann, James Allsopp, Harvey Jenner, Flora Ashley Daniels, Edmund Drage, Yevgeniy Samyshkin, Claude Schmitt, Steven Wood, David G. Kiely, Allan Lawrie
Published 2018-09-01

Utilising artificial intelligence to determine patients at risk of a rare disease: idiopathic pulmonary arterial hypertension

by David G. Kiely, Orla Doyle, Edmund Drage, Harvey Jenner, Valentina Salvatelli, Flora A. Daniels, John Rigg, Claude Schmitt, Yevgeniy Samyshkin, Allan Lawrie, Rito Bergemann
Published 2019-11-01

Differential IL-1 signaling induced by BMPR2 deficiency drives pulmonary vascular remodeling

by Josephine Pickworth, Alexander Rothman, James Iremonger, Helen Casbolt, Kay Hopkinson, Peter M. Hickey, Santhi Gladson, Sheila Shay, Nicholas W. Morrell, Sheila E. Francis, James D. West, Allan Lawrie
Published 2017-09-01

Selective improvement of pulmonary arterial hypertension with a dual ET/ET receptors antagonist in the apolipoprotein E model of PAH and atherosclerosis

by Lewis Renshall, Nadine Arnold, Laura West, Adam Braithwaite, Josephine Pickworth, Rachel Walker, Mabruka Alfaidi, Janet Chamberlain, Helen Casbolt, A.A. Roger Thompson, Cathy Holt, Marc Iglarz, Sheila Francis, Allan Lawrie
Published 2018-01-01

Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension

by Mario Boehm, Nadine Arnold, Adam Braithwaite, Josephine Pickworth, Changwu Lu, Tatyana Novoyatleva, David G. Kiely, Friedrich Grimminger, Hossein A. Ghofrani, Norbert Weissmann, Werner Seeger, Allan Lawrie, Ralph T. Schermuly, Baktybek Kojonazarov
Published 2018-03-01

Elevated plasma CXCL12α is associated with a poorer prognosis in pulmonary arterial hypertension.

by Brian N McCullagh, Christine M Costello, Lili Li, Caroline O'Connell, Mary Codd, Allan Lawrie, Allison Morton, David G Kiely, Robin Condliffe, Charles Elliot, Paul McLoughlin, Sean Gaine
Published 2015-01-01

Expression Quantitative Trait Locus Mapping in Pulmonary Arterial Hypertension

by Anna Ulrich, Pablo Otero-Núñez, John Wharton, Emilia M. Swietlik, Stefan Gräf, Nicholas W. Morrell, Dennis Wang, Allan Lawrie, Martin R. Wilkins, Inga Prokopenko, Christopher J. Rhodes, on behalf of The NIHR BioResource—Rare Diseases Consortium, UK PAH Cohort Study Consortium
Published 2020-10-01

Incremental Shuttle Walking Test Distance Is Reduced in Patients With Pulmonary Hypertension in World Health Organisation Functional Class I

by Catherine G. Billings, Robert Lewis, Iain J. Armstrong, Judith A. Hurdman, Ian A. Smith, Matthew Austin, Charlie A. Elliot, Athanasios Charalampopoulos, Ian Sabroe, Allan Lawrie, A. A. Roger Thompson, Robin Condliffe, David G. Kiely, David G. Kiely, David G. Kiely
Published 2018-06-01

A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach

by Niamh Errington, James Iremonger, Josephine A. Pickworth, Sokratis Kariotis, Christopher J. Rhodes, Alexander MK Rothman, Robin Condliffe, Charles A. Elliot, David G. Kiely, Luke S. Howard, John Wharton, A. A. Roger Thompson, Nicholas W Morrell, Martin R. Wilkins, Dennis Wang, Allan Lawrie
Published 2021-07-01

The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry

by Catherine G. Billings, Robert Lewis, Judith A. Hurdman, Robin Condliffe, Charlie A. Elliot, A.A. Roger Thompson, Ian A. Smith, Matthew Austin, Iain J. Armstrong, Neil Hamilton, Athanasios Charalampopoulos, Ian Sabroe, Andrew J. Swift, Alexander M. Rothman, Jim M. Wild, Allan Lawrie, Judith C. Waterhouse, David G. Kiely
Published 2019-05-01

A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

by Nadine D. Arnold, Josephine A. Pickworth, Laura E. West, Sarah Dawson, Joana A. Carvalho, Helen Casbolt, Adam T. Braithwaite, James Iremonger, Lewis Renshall, Volker Germaschewski, Matthew McCourt, Philip Bland-Ward, Hager Kowash, Abdul G. Hameed, Alexander M. K. Rothman, Maria G. Frid, A. A. Roger Thompson, Holly R. Evans, Mark Southwood, Nicholas W. Morrell, David C. Crossman, Moira K. B. Whyte, Kurt R. Stenmark, Christopher M. Newman, David G. Kiely, Sheila E. Francis, Allan Lawrie
Published 2019-11-01

Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH

by Na Zhu, Emilia M. Swietlik, Carrie L. Welch, Michael W. Pauciulo, Jacob J. Hagen, Xueya Zhou, Yicheng Guo, Johannes Karten, Divya Pandya, Tobias Tilly, Katie A. Lutz, Jennifer M. Martin, Carmen M. Treacy, Erika B. Rosenzweig, Usha Krishnan, Anna W. Coleman, Claudia Gonzaga-Juaregui, Allan Lawrie, Richard C. Trembath, Martin R. Wilkins, Regeneron Genetics Center, PAH Biobank Enrolling Centers’ Investigators, NIHR BioResource for Translational Research - Rare Diseases, National Cohort Study of Idiopathic and Heritable PAH, Nicholas W. Morrell, Yufeng Shen, Stefan Gräf, William C. Nichols, Wendy K. Chung
Published 2021-05-01

Correction to: Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH

by Na Zhu, Emilia M. Swietlik, Carrie L. Welch, Michael W. Pauciulo, Jacob J. Hagen, Xueya Zhou, Yicheng Guo, Johannes Karten, Divya Pandya, Tobias Tilly, Katie A. Lutz, Jennifer M. Martin, Carmen M. Treacy, Erika B. Rosenzweig, Usha Krishnan, Anna W. Coleman, Claudia Gonzaga-Jauregui, Allan Lawrie, Richard C. Trembath, Martin R. Wilkins, Regeneron Genetics Center, PAH Biobank Enrolling Centers’ Investigators, NIHR BioResource for Translational Research - Rare Diseases, National Cohort Study of Idiopathic and Heritable PAH, Nicholas W. Morrell, Yufeng Shen, Stefan Gräf, William C. Nichols, Wendy K. Chung
Published 2021-06-01

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

by Stefan Gräf, Matthias Haimel, Marta Bleda, Charaka Hadinnapola, Laura Southgate, Wei Li, Joshua Hodgson, Bin Liu, Richard M. Salmon, Mark Southwood, Rajiv D. Machado, Jennifer M. Martin, Carmen M. Treacy, Katherine Yates, Louise C. Daugherty, Olga Shamardina, Deborah Whitehorn, Simon Holden, Micheala Aldred, Harm J. Bogaard, Colin Church, Gerry Coghlan, Robin Condliffe, Paul A. Corris, Cesare Danesino, Mélanie Eyries, Henning Gall, Stefano Ghio, Hossein-Ardeschir Ghofrani, J. Simon R. Gibbs, Barbara Girerd, Arjan C. Houweling, Luke Howard, Marc Humbert, David G. Kiely, Gabor Kovacs, Robert V. MacKenzie Ross, Shahin Moledina, David Montani, Michael Newnham, Andrea Olschewski, Horst Olschewski, Andrew J. Peacock, Joanna Pepke-Zaba, Inga Prokopenko, Christopher J. Rhodes, Laura Scelsi, Werner Seeger, Florent Soubrier, Dan F. Stein, Jay Suntharalingam, Emilia M. Swietlik, Mark R. Toshner, David A. van Heel, Anton Vonk Noordegraaf, Quinten Waisfisz, John Wharton, Stephen J. Wort, Willem H. Ouwehand, Nicole Soranzo, Allan Lawrie, Paul D. Upton, Martin R. Wilkins, Richard C. Trembath, Nicholas W. Morrell
Published 2018-04-01

Ultrasound enhanced gene delivery of secreted Interleukin 1 receptor antagonist in a murine vascular injury model

by Ashawesh, Mohamed
Published 2017