Detection of parent-of-origin specific expression quantitative trait loci by cis-association analysis of gene expression in trios.

by Paras Garg, Christelle Borel, Andrew J Sharp
Published 2012-01-01

Comment on "genomic hypomethylation in the human germline associates with selective structural mutability in the human genome".

by Corey T Watson, Paras Garg, Andrew J Sharp
Published 2013-01-01

A survey of inter-individual variation in DNA methylation identifies environmentally responsive co-regulated networks of epigenetic variation in the human genome.

by Paras Garg, Ricky S Joshi, Corey Watson, Andrew J Sharp
Published 2018-10-01

DNA Methylation: Insights into Human Evolution.

by Irene Hernando-Herraez, Raquel Garcia-Perez, Andrew J Sharp, Tomas Marques-Bonet
Published 2015-12-01

Digital genotyping of macrosatellites and multicopy genes reveals novel biological functions associated with copy number variation of large tandem repeats.

by Manisha Brahmachary, Audrey Guilmatre, Javier Quilez, Dan Hasson, Christelle Borel, Peter Warburton, Andrew J Sharp
Published 2014-06-01

Detection of genomic variation by selection of a 9 mb DNA region and high throughput sequencing.

by Sergey I Nikolaev, Christian Iseli, Andrew J Sharp, Daniel Robyr, Jacques Rougemont, Corinne Gehrig, Laurent Farinelli, Stylianos E Antonarakis
Published 2009-01-01

The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.

by Matthieu Raveau, Jacques M Lignon, Valérie Nalesso, Arnaud Duchon, Yoram Groner, Andrew J Sharp, Doulaye Dembele, Véronique Brault, Yann Hérault
Published 2012-05-01

Dynamics of DNA methylation in recent human and great ape evolution.

by Irene Hernando-Herraez, Javier Prado-Martinez, Paras Garg, Marcos Fernandez-Callejo, Holger Heyn, Christina Hvilsom, Arcadi Navarro, Manel Esteller, Andrew J Sharp, Tomas Marques-Bonet
Published 2013-01-01

Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential

by Evan Bardot, Damelys Calderon, Francis Santoriello, Songyan Han, Kakit Cheung, Bharati Jadhav, Ingo Burtscher, Stanley Artap, Rajan Jain, Jonathan Epstein, Heiko Lickert, Valerie Gouon-Evans, Andrew J. Sharp, Nicole C. Dubois
Published 2017-02-01

Opposite phenotypes of muscle strength and locomotor function in mouse models of partial trisomy and monosomy 21 for the proximal Hspa13-App region.

by Véronique Brault, Arnaud Duchon, Caroline Romestaing, Ignasi Sahun, Stéphanie Pothion, Mona Karout, Christelle Borel, Doulaye Dembele, Jean-Charles Bizot, Nadia Messaddeq, Andrew J Sharp, Damien Roussel, Stylianos E Antonarakis, Mara Dierssen, Yann Hérault
Published 2015-03-01

RNA-Seq in 296 phased trios provides a high-resolution map of genomic imprinting

by Bharati Jadhav, Ramin Monajemi, Kristina K. Gagalova, Daniel Ho, Harmen H. M. Draisma, Mark A. van de Wiel, Lude Franke, Bastiaan T. Heijmans, Joyce van Meurs, Rick Jansen, GoNL Consortium, BIOS Consortium, Peter A. C. ‘t Hoen, Andrew J. Sharp, Szymon M. Kiełbasa
Published 2019-06-01

A Novel Framework for Characterizing Genomic Haplotype Diversity in the Human Immunoglobulin Heavy Chain Locus

by Oscar L. Rodriguez, William S. Gibson, Tom Parks, Matthew Emery, James Powell, Maya Strahl, Gintaras Deikus, Kathryn Auckland, Evan E. Eichler, Evan E. Eichler, Wayne A. Marasco, Robert Sebra, Robert Sebra, Andrew J. Sharp, Melissa L. Smith, Melissa L. Smith, Melissa L. Smith, Ali Bashir, Corey T. Watson
Published 2020-09-01

Loss of RNA expression and allele-specific expression associated with congenital heart disease

by David M. McKean, Jason Homsy, Hiroko Wakimoto, Neil Patel, Joshua Gorham, Steven R. DePalma, James S. Ware, Samir Zaidi, Wenji Ma, Nihir Patel, Richard P. Lifton, Wendy K. Chung, Richard Kim, Yufeng Shen, Martina Brueckner, Elizabeth Goldmuntz, Andrew J. Sharp, Christine E. Seidman, Bruce D. Gelb, J. G. Seidman
Published 2016-09-01

Identification of rare de novo epigenetic variations in congenital disorders

by Mafalda Barbosa, Ricky S. Joshi, Paras Garg, Alejandro Martin-Trujillo, Nihir Patel, Bharati Jadhav, Corey T. Watson, William Gibson, Kelsey Chetnik, Chloe Tessereau, Hui Mei, Silvia De Rubeis, Jennifer Reichert, Fatima Lopes, Lisenka E. L. M. Vissers, Tjitske Kleefstra, Dorothy E. Grice, Lisa Edelmann, Gabriela Soares, Patricia Maciel, Han G. Brunner, Joseph D. Buxbaum, Bruce D. Gelb, Andrew J. Sharp
Published 2018-05-01

Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles.

by Alejandro Martin-Trujillo, Nihir Patel, Felix Richter, Bharati Jadhav, Paras Garg, Sarah U Morton, David M McKean, Steven R DePalma, Elizabeth Goldmuntz, Dorota Gruber, Richard Kim, Jane W Newburger, George A Porter, Alessandro Giardini, Daniel Bernstein, Martin Tristani-Firouzi, Jonathan G Seidman, Christine E Seidman, Wendy K Chung, Bruce D Gelb, Andrew J Sharp
Published 2020-11-01

A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex

by Rebecca G. Smith, Ehsan Pishva, Gemma Shireby, Adam R. Smith, Janou A. Y. Roubroeks, Eilis Hannon, Gregory Wheildon, Diego Mastroeni, Gilles Gasparoni, Matthias Riemenschneider, Armin Giese, Andrew J. Sharp, Leonard Schalkwyk, Vahram Haroutunian, Wolfgang Viechtbauer, Daniel L. A. van den Hove, Michael Weedon, Danielle Brokaw, Paul T. Francis, Alan J. Thomas, Seth Love, Kevin Morgan, Jörn Walter, Paul D. Coleman, David A. Bennett, Philip L. De Jager, Jonathan Mill, Katie Lunnon
Published 2021-06-01