FGF21 requires βklotho to act in vivo.

by Andrew C Adams, Christine C Cheng, Tamer Coskun, Alexei Kharitonenkov
Published 2012-01-01

Discrete Aspects of FGF21 In Vivo Pharmacology Do Not Require UCP1

by Ricardo J. Samms, Dennis P. Smith, Christine C. Cheng, Patrick P. Antonellis, James W. Perfield 2nd, Alexei Kharitonenkov, Ruth E. Gimeno, Andrew C. Adams
Published 2015-05-01

Novel Small Molecule Agonist of TGR5 Possesses Anti-Diabetic Effects but Causes Gallbladder Filling in Mice.

by Daniel A Briere, Xiaoping Ruan, Christine C Cheng, Angela M Siesky, Thomas E Fitch, Carmen Dominguez, Sonia Gutierrez Sanfeliciano, Carlos Montero, Chen S Suen, Yanping Xu, Tamer Coskun, M Dodson Michael
Published 2015-01-01

Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319.

by Alexei Kharitonenkov, John M Beals, Radmila Micanovic, Beth A Strifler, Radhakrishnan Rathnachalam, Victor J Wroblewski, Shun Li, Anja Koester, Amy M Ford, Tamer Coskun, James D Dunbar, Christine C Cheng, Christopher C Frye, Thomas F Bumol, David E Moller
Published 2013-01-01