Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice[S]

by Youcai Zhang, Curtis D. Klaassen
Published 2010-11-01

Gender-divergent profile of bile acid homeostasis during aging of mice.

by Zidong Donna Fu, Iván L Csanaky, Curtis D Klaassen
Published 2012-01-01

Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver.

by Kai Connie Wu, Julia Yue Cui, Curtis D Klaassen
Published 2012-01-01

The Role of Sirt1 in Bile Acid Regulation during Calorie Restriction in Mice.

by Zidong Donna Fu, Julia Yue Cui, Curtis D Klaassen
Published 2015-01-01

Atorvastatin induces bile acid-synthetic enzyme Cyp7a1 by suppressing FXR signaling in both liver and intestine in mice[S]

by Zidong Donna Fu, Julia Yue Cui, Curtis D. Klaassen
Published 2014-12-01

Genetic activation of Nrf2 protects against fasting-induced oxidative stress in livers of mice.

by Yu-Kun Jennifer Zhang, Kai Connie Wu, Curtis D Klaassen
Published 2013-01-01

Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters.

by Yu-Kun Jennifer Zhang, Grace L Guo, Curtis D Klaassen
Published 2011-02-01

Effect of diet on expression of genes involved in lipid metabolism, oxidative stress, and inflammation in mouse liver-insights into mechanisms of hepatic steatosis.

by Helen J Renaud, Julia Y Cui, Hong Lu, Curtis D Klaassen
Published 2014-01-01

Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism in mice.

by Youcai Zhang, Pallavi B Limaye, Lois D Lehman-McKeeman, Curtis D Klaassen
Published 2012-01-01

NRF2 Protection against Liver Injury Produced by Various Hepatotoxicants

by Jie Liu, Kai Connie Wu, Yuan-Fu Lu, Edugie Ekuase, Curtis D. Klaassen
Published 2013-01-01

Ontogeny of hepatic energy metabolism genes in mice as revealed by RNA-sequencing.

by Helen J Renaud, Yue Julia Cui, Hong Lu, Xiao-bo Zhong, Curtis D Klaassen
Published 2014-01-01

Overexpression of Nrf2 protects against microcystin-induced hepatotoxicity in mice.

by Yuan-Fu Lu, Jie Liu, Kai Connie Wu, Qiang Qu, Fang Fan, Curtis D Klaassen
Published 2014-01-01

Implementation of a high-throughput screen for identifying small molecules to activate the Keap1-Nrf2-ARE pathway.

by Kai Connie Wu, Peter R McDonald, Jie Jerry Liu, Rathnam Chaguturu, Curtis D Klaassen
Published 2012-01-01

Deciphering the Developmental Dynamics of the Mouse Liver Transcriptome.

by Sumedha S Gunewardena, Byunggil Yoo, Lai Peng, Hong Lu, Xiaobo Zhong, Curtis D Klaassen, Julia Yue Cui
Published 2015-01-01

Diurnal variation of hepatic antioxidant gene expression in mice.

by Yi-Qiao Xu, Dan Zhang, Tao Jin, Ding-Jun Cai, Qin Wu, Yuanfu Lu, Jie Liu, Curtis D Klaassen
Published 2012-01-01

Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor.

by John Rooney, Keiyu Oshida, Naresh Vasani, Beena Vallanat, Natalia Ryan, Brian N Chorley, Xuting Wang, Douglas A Bell, Kai C Wu, Lauren M Aleksunes, Curtis D Klaassen, Thomas W Kensler, J Christopher Corton
Published 2018-01-01

Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs, gut microbiota, and diseases: a meeting report of the 21st International Symposium...

by Ai-Ming Yu, Magnus Ingelman-Sundberg, Nathan J. Cherrington, Lauren M. Aleksunes, Ulrich M. Zanger, Wen Xie, Hyunyoung Jeong, Edward M. Morgan, Peter J. Turnbaugh, Curtis D. Klaassen, Aadra P. Bhatt, Matthew R. Redinbo, Pengying Hao, David J. Waxman, Li Wang, Xiao-bo Zhong
Published 2017-03-01