Towards a New Diagnostic Standard for Niemann–Pick C Disease

by Xuntian Jiang, Daniel S. Ory
Published 2016-02-01

Fatty acid transport protein 1 and long-chain acyl coenzyme A synthetase 1 interact in adipocytes

by M. Rachel Richards, Jeffrey D. Harp, Daniel S. Ory, Jean E. Schaffer
Published 2006-03-01

Niemann-Pick Type C Disease Reveals a Link between Lysosomal Cholesterol and PtdIns(4,5)P2 That Regulates Neuronal Excitability

by Oscar Vivas, Scott A. Tiscione, Rose E. Dixon, Daniel S. Ory, Eamonn J. Dickson
Published 2019-05-01

Monitoring the itinerary of lysosomal cholesterol in Niemann-Pick Type C1-deficient cells after cyclodextrin treatment[S]

by McKenna Feltes, Sarah E. Gale, Samantha Moores, Daniel S. Ory, Jean E. Schaffer
Published 2020-03-01

Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death

by Nica M. Borradaile, Xianlin Han, Jeffrey D. Harp, Sarah E. Gale, Daniel S. Ory, Jean E. Schaffer
Published 2006-12-01

A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson's disease

by Elma Aflaki, Barbara K. Stubblefield, Ryan P. McGlinchey, Benjamin McMahon, Daniel S. Ory, Ellen Sidransky
Published 2020-02-01

Neurologic abnormalities in mouse models of the lysosomal storage disorders mucolipidosis II and mucolipidosis III γ.

by Rachel A Idol, David F Wozniak, Hideji Fujiwara, Carla M Yuede, Daniel S Ory, Stuart Kornfeld, Peter Vogel
Published 2014-01-01

Alterations in plasma triglycerides and ceramides: links with cardiac function in humans with type 2 diabetes

by Linda R. Peterson, Xuntian Jiang, Ling Chen, Anne C. Goldberg, Marsha S. Farmer, Daniel S. Ory, Jean E. Schaffer
Published 2020-07-01

Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration

by Norimitsu Ban, Tae Jun Lee, Abdoulaye Sene, Zhenyu Dong, Andrea Santeford, Jonathan B. Lin, Daniel S. Ory, Rajendra S. Apte
Published 2018-08-01

The steroidal analog GW707 activates the SREBP pathway through disruption of intracellular cholesterol trafficking

by Jessie Zhang, Nicole Dudley-Rucker, Jan R. Crowley, Elvira Lopez-Perez, Marc Issandou, Jean E. Schaffer, Daniel S. Ory
Published 2004-02-01

Psychosine, the cytotoxic sphingolipid that accumulates in globoid cell leukodystrophy, alters membrane architecture

by Jacqueline A. Hawkins-Salsbury, Archana R. Parameswar, Xuntian Jiang, Paul H. Schlesinger, Ernesto Bongarzone, Daniel S. Ory, Alexei V. Demchenko, Mark S. Sands
Published 2013-12-01

Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression.

by Cristin D Davidson, Nafeeza F Ali, Matthew C Micsenyi, Gloria Stephney, Sophie Renault, Kostantin Dobrenis, Daniel S Ory, Marie T Vanier, Steven U Walkley
Published 2009-09-01

Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking[S]

by McKenna Feltes, Samantha Moores, Sarah E. Gale, Kathiresan Krishnan, Laurel Mydock-McGrane, Douglas F. Covey, Daniel S. Ory, Jean E. Schaffer
Published 2019-03-01

A validated LC-MS/MS assay for quantification of 24(S)-hydroxycholesterol in plasma and cerebrospinal fluid

by Rohini Sidhu, Hui Jiang, Nicole Y. Farhat, Nuria Carrillo-Carrasco, Myra Woolery, Elizabeth Ottinger, Forbes D. Porter, Jean E. Schaffer, Daniel S. Ory, Xuntian Jiang
Published 2015-06-01

Oxysterol Signatures Distinguish Age-Related Macular Degeneration from Physiologic Aging

by Jonathan B. Lin, Abdoulaye Sene, Andrea Santeford, Hideji Fujiwara, Rohini Sidhu, Marianne M. Ligon, Vikram A. Shankar, Norimitsu Ban, Indira U. Mysorekar, Daniel S. Ory, Rajendra S. Apte
Published 2018-06-01

A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1

by Anika V. Prabhu, Insung Kang, Raffaella De Pace, Christopher A. Wassif, Hideji Fujiwara, Pamela Kell, Xuntian Jiang, Daniel S. Ory, Juan S. Bonifacino, Michael E. Ward, Forbes D. Porter
Published 2021-10-01

A novel intrinsically fluorescent probe for study of uptake and trafficking of 25-hydroxycholesterol

by David B. Iaea, Sarah E. Gale, Agata A. Bielska, Kathiresan Krishnan, Hideji Fujiwara, Hui Jiang, Frederick R. Maxfield, Paul H. Schlesinger, Douglas F. Covey, Jean E. Schaffer, Daniel S. Ory
Published 2015-12-01

Lipidomic Evaluation of Feline Neurologic Disease after AAV Gene Therapy

by Heather L. Gray-Edwards, Xuntian Jiang, Ashley N. Randle, Amanda R. Taylor, Taylor L. Voss, Aime K. Johnson, Victoria J. McCurdy, Miguel Sena-Esteves, Daniel S. Ory, Douglas R. Martin
Published 2017-09-01

Identification of Niemann-Pick C1 disease biomarkers through sphingolipid profiling

by Martin Fan, Rohini Sidhu, Hideji Fujiwara, Brett Tortelli, Jessie Zhang, Cristin Davidson, Steven U. Walkley, Jessica H. Bagel, Charles Vite, Nicole M. Yanjanin, Forbes D. Porter, Jean E. Schaffer, Daniel S. Ory
Published 2013-10-01

Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis

by Arthur C. Sletten, Jessica W. Davidson, Busra Yagabasan, Samantha Moores, Michaela Schwaiger-Haber, Hideji Fujiwara, Sarah Gale, Xuntian Jiang, Rohini Sidhu, Susan Gelman, Shuang Zhao, Gary Patti, Daniel S. Ory, Jean E. Schaffer
Published 2021-09-01