PTMphinder: an R package for PTM site localization and motif extraction from proteomic datasets

by Jacob M. Wozniak, David J. Gonzalez
Published 2019-06-01

Identification of the S-transferase like superfamily bacillithiol transferases encoded by Bacillus subtilis.

by Varahenage R Perera, John D Lapek, Gerald L Newton, David J Gonzalez, Kit Pogliano
Published 2018-01-01

Exposure of <i>Mycobacterium abscessus</i> to Environmental Stress and Clinically Used Antibiotics Reveals Common Proteome Response among Pathogenic Mycobacteria

by Rajoana Rojony, Lia Danelishvili, Anaamika Campeau, Jacob M. Wozniak, David J. Gonzalez, Luiz E. Bermudez
Published 2020-05-01

Dissociation of DNA damage sensing by endoglycosidase HPSE

by Alex Agelidis, Rahul K. Suryawanshi, Chandrashekhar D. Patil, Anaamika Campeau, David J. Gonzalez, Deepak Shukla
Published 2021-03-01

Functional and Proteomic Analysis of Streptococcus pyogenes Virulence Upon Loss of Its Native Cas9 Nuclease

by Nina J. Gao, Nina J. Gao, Mahmoud M. Al-Bassam, Saugat Poudel, Saugat Poudel, Saugat Poudel, Jacob M. Wozniak, Jacob M. Wozniak, David J. Gonzalez, David J. Gonzalez, Joshua Olson, Karsten Zengler, Karsten Zengler, Victor Nizet, Victor Nizet, J. Andrés Valderrama
Published 2019-08-01

A Cdk4/6-dependent phosphorylation gradient regulates the early to late G1 phase transition

by Manuel Kaulich, Verena M. Link, John D. Lapek, Yeon J. Lee, Christopher K. Glass, David J. Gonzalez, Steven F. Dowdy
Published 2021-07-01

Fermentable fiber-induced hepatocellular carcinoma in mice recapitulates gene signatures found in human liver cancer.

by Darshan Shimoga Chandrashekar, Rachel M Golonka, Beng San Yeoh, David J Gonzalez, Mathias Heikenwälder, Andrew T Gerwirtz, Sooryanarayana Varambally, Matam Vijay-Kumar
Published 2020-01-01

Evaluating Metagenomic Prediction of the Metaproteome in a 4.5-Year Study of a Patient with Crohn's Disease

by Robert H. Mills, Yoshiki Vázquez-Baeza, Qiyun Zhu, Lingjing Jiang, James Gaffney, Greg Humphrey, Larry Smarr, Rob Knight, David J. Gonzalez
Published 2019-02-01

Optimization of carbon and energy utilization through differential translational efficiency

by Mahmoud M. Al-Bassam, Ji-Nu Kim, Livia S. Zaramela, Benjamin P. Kellman, Cristal Zuniga, Jacob M. Wozniak, David J. Gonzalez, Karsten Zengler
Published 2018-10-01

Molecular dissection of Chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways.

by Jacob M Wozniak, Tatiana Araújo Silva, Diane Thomas, Jair L Siqueira-Neto, James H McKerrow, David J Gonzalez, Claudia M Calvet
Published 2020-05-01

A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling

by Neil J. Grimsey, Rachan Narala, Cara C. Rada, Sohum Mehta, Bryan S. Stephens, Irina Kufareva, John Lapek, David J. Gonzalez, Tracy M. Handel, Jin Zhang, JoAnn Trejo
Published 2018-09-01

Unique virulence role of post-translocational chaperone PrsA in shaping Streptococcus pyogenes secretome

by Zhao-Yi Wu, Anaamika Campeau, Chao-Hsien Liu, David J. Gonzalez, Masaya Yamaguchi, Shigetada Kawabata, Chieh-Hsien Lu, Chian-Yu Lai, Hao-Chieh Chiu, Yung-Chi Chang
Published 2021-01-01

Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models

by Fatemeh Askarian, Fatemeh Askarian, John D. Lapek, Mitesh Dongre, Chih-Ming Tsai, Monika Kumaraswamy, Armin Kousha, Armin Kousha, J. Andrés Valderrama, Judith A. Ludviksen, Jorunn P. Cavanagh, Jorunn P. Cavanagh, Satoshi Uchiyama, Tom E. Mollnes, Tom E. Mollnes, Tom E. Mollnes, Tom E. Mollnes, Tom E. Mollnes, David J. Gonzalez, David J. Gonzalez, Sun N. Wai, Victor Nizet, Victor Nizet, Mona Johannessen
Published 2018-02-01

A Hetero-Multimeric Chitinase-Containing Plasmodium falciparum and Plasmodium gallinaceum Ookinete-Secreted Protein Complex Involved in Mosquito Midgut Invasion

by Kailash P. Patra, Hargobinder Kaur, Surendra Kumar Kolli, Jacob M. Wozniak, Judith Helena Prieto, Judith Helena Prieto, John R. Yates, David J. Gonzalez, Chris J. Janse, Joseph M. Vinetz
Published 2021-01-01

Multidimensional Proteome Profiling of Blood-Brain Barrier Perturbation by Group B Streptococcus

by Anaamika Campeau, Robert H. Mills, Marie Blanchette, Kaja Bajc, Mario Malfavon, Roeben N. Munji, Liwen Deng, Bryan Hancock, Kathryn A. Patras, Joshua Olson, Victor Nizet, Richard Daneman, Kelly Doran, David J. Gonzalez
Published 2020-08-01

Group A Streptococcal S Protein Utilizes Red Blood Cells as Immune Camouflage and Is a Critical Determinant for Immune Evasion

by Igor H. Wierzbicki, Anaamika Campeau, Diana Dehaini, Maya Holay, Xiaoli Wei, Trever Greene, Man Ying, Jenna S. Sands, Anne Lamsa, Elina Zuniga, Kit Pogliano, Ronnie H. Fang, Christopher N. LaRock, Liangfang Zhang, David J. Gonzalez
Published 2019-12-01

Essential metabolism for a minimal cell

by Marian Breuer, Tyler M Earnest, Chuck Merryman, Kim S Wise, Lijie Sun, Michaela R Lynott, Clyde A Hutchison, Hamilton O Smith, John D Lapek, David J Gonzalez, Valérie de Crécy-Lagard, Drago Haas, Andrew D Hanson, Piyush Labhsetwar, John I Glass, Zaida Luthey-Schulten
Published 2019-01-01

Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome

by Robert A. Quinn, Sandeep Adem, Robert H. Mills, William Comstock, Lindsay DeRight Goldasich, Gregory Humphrey, Alexander A. Aksenov, Alexei V. Melnik, Ricardo da Silva, Gail Ackermann, Nuno Bandeira, David J. Gonzalez, Doug Conrad, Anthony J. O’Donoghue, Rob Knight, Pieter C. Dorrestein
Published 2019-02-01

Urinary Exosomes Identify Inflammatory Pathways in Vancomycin Associated Acute Kidney Injury

by Linda Awdishu, Amy Le, Jordan Amato, Vidhyut Jani, Soma Bal, Robert H. Mills, Marvic Carrillo-Terrazas, David J. Gonzalez, Ashita Tolwani, Anjali Acharya, Jorge Cerda, Melanie S. Joy, Paola Nicoletti, Etienne Macedo, Sucheta Vaingankar, Ravindra Mehta, Satish P. RamachandraRao, on behalf of the Direct Investigators
Published 2021-03-01

Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival

by Alex Agelidis, Benjamin A. Turturice, Rahul K. Suryawanshi, Tejabhiram Yadavalli, Dinesh Jaishankar, Joshua Ames, James Hopkins, Lulia Koujah, Chandrashekhar D. Patil, Satvik R. Hadigal, Evan J. Kyzar, Anaamika Campeau, Jacob M. Wozniak, David J. Gonzalez, Israel Vlodavsky, Jin-ping Li, David L. Perkins, Patricia W. Finn, Deepak Shukla
Published 2021-04-01