KLF15 and PPARα Cooperate to Regulate Cardiomyocyte Lipid Gene Expression and Oxidation

by Domenick A. Prosdocimo, Jenine E. John, Lilei Zhang, Elizabeth S. Efraim, Rongli Zhang, Xudong Liao, Mukesh K. Jain
Published 2015-01-01

ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects

by Yuanyuan Zhao, Xiaoyan Sun, Di Hu, Domenick A. Prosdocimo, Charles Hoppel, Mukesh K. Jain, Rajesh Ramachandran, Xin Qi
Published 2019-03-01

Adipose KLF15 Controls Lipid Handling to Adapt to Nutrient Availability

by Keiichiro Matoba, Yuan Lu, Rongli Zhang, Eric R. Chen, Panjamaporn Sangwung, Benlian Wang, Domenick A. Prosdocimo, Mukesh K. Jain
Published 2017-12-01

KLF15 Establishes the Landscape of Diurnal Expression in the Heart

by Lilei Zhang, Domenick A. Prosdocimo, Xiaodong Bai, Chen Fu, Rongli Zhang, Frank Campbell, Xudong Liao, Jeff Coller, Mukesh K. Jain
Published 2015-12-01

Kruppel-like factor 15 is required for the cardiac adaptive response to fasting.

by Keiki Sugi, Paishiun N Hsieh, Olga Ilkayeva, Shamanthika Shelkay, Bridget Moroney, Palvir Baadh, Browning Haynes, Megan Pophal, Liyan Fan, Christopher B Newgard, Domenick A Prosdocimo, Mukesh K Jain
Published 2018-01-01

A conserved KLF-autophagy pathway modulates nematode lifespan and mammalian age-associated vascular dysfunction

by Paishiun N. Hsieh, Guangjin Zhou, Yiyuan Yuan, Rongli Zhang, Domenick A. Prosdocimo, Panjamaporn Sangwung, Anna H. Borton, Evgenii Boriushkin, Anne Hamik, Hisashi Fujioka, Ciaran E. Fealy, John P. Kirwan, Maureen Peters, Yuan Lu, Xudong Liao, Diana Ramírez-Bergeron, Zhaoyang Feng, Mukesh K. Jain
Published 2017-10-01

KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance.

by Dae Young Jung, Umadevi Chalasani, Ning Pan, Randall H Friedline, Domenick A Prosdocimo, Minwoo Nam, Yoshihiro Azuma, Rajanikanth Maganti, Kristine Yu, Ashish Velagapudi, Bryan O'Sullivan-Murphy, Juliano L Sartoretto, Mukesh K Jain, Marcus P Cooper, Fumihiko Urano, Jason K Kim, Susan Gray
Published 2013-01-01

Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice

by Lisa M. Walter, Marc-Olivier Deguise, Katharina E. Meijboom, Corinne A. Betts, Nina Ahlskog, Tirsa L.E. van Westering, Gareth Hazell, Emily McFall, Anna Kordala, Suzan M. Hammond, Frank Abendroth, Lyndsay M. Murray, Hannah K. Shorrock, Domenick A. Prosdocimo, Saptarsi M. Haldar, Mukesh K. Jain, Thomas H. Gillingwater, Peter Claus, Rashmi Kothary, Matthew J.A. Wood, Melissa Bowerman
Published 2018-05-01