Systems modelling of NHEJ reveals the importance of redox regulation of Ku70/80 in the dynamics of dna damage foci.

by David Dolan, Glyn Nelson, Anze Zupanic, Graham Smith, Daryl Shanley
Published 2013-01-01

Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis.

by Chatchawan Singhapol, Deepali Pal, Rafal Czapiewski, Mahendar Porika, Glyn Nelson, Gabriele C Saretzki
Published 2013-01-01

Integrated Stochastic Model of DNA Damage Repair by Non-homologous End Joining and p53/p21-Mediated Early Senescence Signalling.

by David W P Dolan, Anze Zupanic, Glyn Nelson, Philip Hall, Satomi Miwa, Thomas B L Kirkwood, Daryl P Shanley
Published 2015-05-01

Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions.

by Piero Dalle Pezze, Glyn Nelson, Elsje G Otten, Viktor I Korolchuk, Thomas B L Kirkwood, Thomas von Zglinicki, Daryl P Shanley
Published 2014-08-01

Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence.

by João F Passos, Gabriele Saretzki, Shaheda Ahmed, Glyn Nelson, Torsten Richter, Heiko Peters, Ilka Wappler, Matthew J Birket, Graham Harold, Karin Schaeuble, Mark A Birch-Machin, Thomas B L Kirkwood, Thomas von Zglinicki
Published 2007-05-01