Modelling the response of FOXO transcription factors to multiple post-translational modifications made by ageing-related signalling pathways.

by Graham R Smith, Daryl P Shanley
Published 2010-06-01

Integrated Stochastic Model of DNA Damage Repair by Non-homologous End Joining and p53/p21-Mediated Early Senescence Signalling.

by David W P Dolan, Anze Zupanic, Glyn Nelson, Philip Hall, Satomi Miwa, Thomas B L Kirkwood, Daryl P Shanley
Published 2015-05-01

Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions.

by Piero Dalle Pezze, Glyn Nelson, Elsje G Otten, Viktor I Korolchuk, Thomas B L Kirkwood, Thomas von Zglinicki, Daryl P Shanley
Published 2014-08-01

Predominant Asymmetrical Stem Cell Fate Outcome Limits the Rate of Niche Succession in Human Colonic Crypts

by Craig Stamp, Anze Zupanic, Ashwin Sachdeva, Elizabeth A. Stoll, Daryl P. Shanley, John C. Mathers, Thomas B.L. Kirkwood, Rakesh Heer, Benjamin D. Simons, Doug M. Turnbull, Laura C. Greaves
Published 2018-05-01

A systems study reveals concurrent activation of AMPK and mTOR by amino acids

by Piero Dalle Pezze, Stefanie Ruf, Annika G. Sonntag, Miriam Langelaar-Makkinje, Philip Hall, Alexander M. Heberle, Patricia Razquin Navas, Karen van Eunen, Regine C. Tölle, Jennifer J. Schwarz, Heike Wiese, Bettina Warscheid, Jana Deitersen, Björn Stork, Erik Fäßler, Sascha Schäuble, Udo Hahn, Peter Horvatovich, Daryl P. Shanley, Kathrin Thedieck
Published 2016-11-01