Diagnostic Test Criteria for HLA Genotyping to Prevent Drug Hypersensitivity Reactions: A Systematic Review of Actionable HLA Recommendations in CPIC and DPWG Guidelines

by Lisanne E. N. Manson, Lisanne E. N. Manson, Jesse J. Swen, Jesse J. Swen, Henk-Jan Guchelaar, Henk-Jan Guchelaar
Published 2020-09-01

Applying Next-Generation Sequencing Platforms for Pharmacogenomic Testing in Clinical Practice

by Alireza Tafazoli, Alireza Tafazoli, Henk-Jan Guchelaar, Henk-Jan Guchelaar, Wojciech Miltyk, Adam J. Kretowski, Adam J. Kretowski, Jesse J. Swen, Jesse J. Swen
Published 2021-08-01

Clinical development of gene- and cell-based therapies: overview of the European landscape

by Sofieke de Wilde, Henk-Jan Guchelaar, Maarten Laurens Zandvliet, Pauline Meij
Published 2016-01-01

Phenoconversion of Cytochrome P450 Metabolism: A Systematic Review

by Sylvia D. Klomp, Martijn L. Manson, Henk-Jan Guchelaar, Jesse J. Swen
Published 2020-09-01

Technologies for Pharmacogenomics: A Review

by Maaike van der Lee, Marjolein Kriek, Henk-Jan Guchelaar, Jesse J. Swen
Published 2020-12-01

Genetic Variants in DNA Repair Pathways as Potential Biomarkers in Predicting Treatment Outcome of Intraperitoneal Chemotherapy in Patients With Colorectal Peritoneal Metastasis: A...

by Emma C. Hulshof, Emma C. Hulshof, Lifani Lim, Ignace H. J. T. de Hingh, Ignace H. J. T. de Hingh, Hans Gelderblom, Henk-Jan Guchelaar, Henk-Jan Guchelaar, Maarten J. Deenen, Maarten J. Deenen
Published 2020-10-01

Genome wide association study to identify predictors for severe skin toxicity in colorectal cancer patients treated with cetuximab.

by Jara Baas, Lisanne Krens, Stefan Bohringer, Linda Mol, Cornelis Punt, Henk-Jan Guchelaar, Hans Gelderblom
Published 2018-01-01

Pharmacist-Initiated Pre-Emptive Pharmacogenetic Panel Testing with Clinical Decision Support in Primary Care: Record of PGx Results and Real-World Impact

by Cathelijne H. van der Wouden, Paul C. D. Bank, Kübra Özokcu, Jesse J. Swen, Henk-Jan Guchelaar
Published 2019-05-01

Assessing the Implementation of Pharmacogenomic Panel-Testing in Primary Care in the Netherlands Utilizing a Theoretical Framework

by Cathelijne H. van der Wouden, Ellen Paasman, Martina Teichert, Matty R. Crone, Henk-Jan Guchelaar, Jesse J. Swen
Published 2020-03-01

A Review of Mathematical Models for Tumor Dynamics and Treatment Resistance Evolution of Solid Tumors

by Anyue Yin, Dirk Jan A.R. Moes, Johan G.C. vanHasselt, Jesse J. Swen, Henk‐Jan Guchelaar
Published 2019-10-01

Genome Wide Association Study for Predictors of Progression Free Survival in Patients on Capecitabine, Oxaliplatin, Bevacizumab and Cetuximab in First-Line Therapy of Metastatic Co...

by Jan Pander, Lieke van Huis-Tanja, Stefan Böhringer, Tahar van der Straaten, Hans Gelderblom, Cornelis Punt, Henk-Jan Guchelaar
Published 2015-01-01

Translating pharmacogenomics: challenges on the road to the clinic.

by Jesse J Swen, Tom W Huizinga, Hans Gelderblom, Elisabeth G E de Vries, Willem J J Assendelft, Julia Kirchheiner, Henk-Jan Guchelaar
Published 2007-08-01

Statin use is not associated with improved progression free survival in cetuximab treated KRAS mutant metastatic colorectal cancer patients: results from the CAIRO2 study.

by Lisanne L Krens, Lieke H J Simkens, Jara M Baas, Els R Koomen, Hans Gelderblom, Cornelis J A Punt, Henk-Jan Guchelaar
Published 2014-01-01

Diagnostic and Therapeutic Strategies for Fluoropyrimidine Treatment of Patients Carrying Multiple <i>DPYD</i> Variants

by Carin A. T. C. Lunenburg, Linda M. Henricks, André B. P. van Kuilenburg, Ron H. J. Mathijssen, Jan H. M. Schellens, Hans Gelderblom, Henk-Jan Guchelaar, Jesse J. Swen
Published 2018-11-01

The variant T allele of PvuII in ESR1 gene is a prognostic marker in early breast cancer survival

by Danny Houtsma, Stefanie de Groot, Renee Baak-Pablo, Elma Meershoek -Klein Kranenbarg, Caroline M. Seynaeve, Cornelis J. H. van de Velde, Stefan Böhringer, Judith R. Kroep, Henk -Jan Guchelaar, Hans Gelderblom
Published 2021-02-01

Treosulfan-induced myalgia in pediatric hematopoietic stem cell transplantation identified by an electronic health record text mining tool

by M. Y. Eileen C. van der Stoep, Dagmar Berghuis, Robbert G. M. Bredius, Emilie P. Buddingh, Alexander B. Mohseny, Frans J. W. Smiers, Henk-Jan Guchelaar, Arjan C. Lankester, Juliette Zwaveling
Published 2021-09-01

Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Gr...

by Kelly E. Caudle, Katrin Sangkuhl, Michelle Whirl‐Carrillo, Jesse J. Swen, Cyrine E. Haidar, Teri E. Klein, Roseann S. Gammal, Mary V. Relling, Stuart A. Scott, Daniel L. Hertz, Henk‐Jan Guchelaar, Andrea Gaedigk
Published 2020-01-01

Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data.

by Jeffrey J W Verschuren, Stella Trompet, Joris Deelen, David J Stott, Naveed Sattar, Brendan M Buckley, Ian Ford, Bastiaan T Heijmans, Henk-Jan Guchelaar, Jeanine J Houwing-Duistermaat, P Eline Slagboom, J Wouter Jukema
Published 2013-01-01

Analysis of Drug Metabolizing Gene Panel in Osteosarcoma Patients Identifies Association Between Variants in SULT1E1, CYP2B6 and CYP4F8 and Methotrexate Levels and Toxicities

by Evelien G. E. Hurkmans, Marije J. Klumpers, Sita H. Vermeulen, Melanie M. Hagleitner, Uta Flucke, H. W. Bart Schreuder, Hans Gelderblom, Johannes Bras, Henk-Jan Guchelaar, Marieke J. H. Coenen, D. Maroeska W. M. te Loo
Published 2020-08-01

Learning From Consultations Conducted by Community Pharmacists in Northern Ireland for Nonprescription Sildenafil: A Qualitative Study Using the Theoretical Domains Framework

by Rineke Gordijn, PharmD, Martina Teichert, PharmD, PhD, Melianthe P.J. Nicolai, MD, PhD, Henk W. Elzevier, MD, PhD, Henk-Jan Guchelaar, PharmD, PhD, Carmel M. Hughes, PharmD, PhD
Published 2021-12-01