A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach.

by Matthew Traylor, Kari-Matti Mäkelä, Laura L Kilarski, Elizabeth G Holliday, William J Devan, Mike A Nalls, Kerri L Wiggins, Wei Zhao, Yu-Ching Cheng, Sefanja Achterberg, Rainer Malik, Cathie Sudlow, Steve Bevan, Emma Raitoharju, METASTROKE, International Stroke Genetics Consortium, Wellcome Trust Case Consortium 2 (WTCCC2), Niku Oksala, Vincent Thijs, Robin Lemmens, Arne Lindgren, Agnieszka Slowik, Jane M Maguire, Matthew Walters, Ale Algra, Pankaj Sharma, John R Attia, Giorgio B Boncoraglio, Peter M Rothwell, Paul I W de Bakker, Joshua C Bis, Danish Saleheen, Steven J Kittner, Braxton D Mitchell, Jonathan Rosand, James F Meschia, Christopher Levi, Martin Dichgans, Terho Lehtimäki, Cathryn M Lewis, Hugh S Markus
Published 2014-07-01

Outcome after acute ischemic stroke is linked to sex-specific lesion patterns

by Anna K. Bonkhoff, Markus D. Schirmer, Martin Bretzner, Sungmin Hong, Robert W. Regenhardt, Mikael Brudfors, Kathleen L. Donahue, Marco J. Nardin, Adrian V. Dalca, Anne-Katrin Giese, Mark R. Etherton, Brandon L. Hancock, Steven J. T. Mocking, Elissa C. McIntosh, John Attia, Oscar R. Benavente, Stephen Bevan, John W. Cole, Amanda Donatti, Christoph J. Griessenauer, Laura Heitsch, Lukas Holmegaard, Katarina Jood, Jordi Jimenez-Conde, Steven J. Kittner, Robin Lemmens, Christopher R. Levi, Caitrin W. McDonough, James F. Meschia, Chia-Ling Phuah, Arndt Rolfs, Stefan Ropele, Jonathan Rosand, Jaume Roquer, Tatjana Rundek, Ralph L. Sacco, Reinhold Schmidt, Pankaj Sharma, Agnieszka Slowik, Martin Söderholm, Alessandro Sousa, Tara M. Stanne, Daniel Strbian, Turgut Tatlisumak, Vincent Thijs, Achala Vagal, Johan Wasselius, Daniel Woo, Ramin Zand, Patrick F. McArdle, Bradford B. Worrall, Christina Jern, Arne G. Lindgren, Jane Maguire, Danilo Bzdok, Ona Wu, MRI-GENIE and GISCOME Investigators and the International Stroke Genetics Consortium, Natalia S. Rost
Published 2021-06-01

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.

by Bram P Prins, Ali Abbasi, Anson Wong, Ahmad Vaez, Ilja Nolte, Nora Franceschini, Philip E Stuart, Javier Guterriez Achury, Vanisha Mistry, Jonathan P Bradfield, Ana M Valdes, Jose Bras, Aleksey Shatunov, PAGE Consortium, International Stroke Genetics Consortium, Systemic Sclerosis consortium, Treat OA consortium, DIAGRAM Consortium, CARDIoGRAMplusC4D Consortium, ALS consortium, International Parkinson’s Disease Genomics Consortium, Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, CKDGen consortium, GERAD1 Consortium, International Consortium for Blood Pressure, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Inflammation Working Group of the CHARGE Consortium, Chen Lu, Buhm Han, Soumya Raychaudhuri, Steve Bevan, Maureen D Mayes, Lam C Tsoi, Evangelos Evangelou, Rajan P Nair, Struan F A Grant, Constantin Polychronakos, Timothy R D Radstake, David A van Heel, Melanie L Dunstan, Nicholas W Wood, Ammar Al-Chalabi, Abbas Dehghan, Hakon Hakonarson, Hugh S Markus, James T Elder, Jo Knight, Dan E Arking, Timothy D Spector, Bobby P C Koeleman, Cornelia M van Duijn, Javier Martin, Andrew P Morris, Rinse K Weersma, Cisca Wijmenga, Patricia B Munroe, John R B Perry, Jennie G Pouget, Yalda Jamshidi, Harold Snieder, Behrooz Z Alizadeh
Published 2016-06-01

Excessive White Matter Hyperintensity Increases Susceptibility to Poor Functional Outcomes After Acute Ischemic Stroke

by Sungmin Hong, Anne-Katrin Giese, Markus D. Schirmer, Markus D. Schirmer, Anna K. Bonkhoff, Martin Bretzner, Martin Bretzner, Pamela Rist, Adrian V. Dalca, Adrian V. Dalca, Robert W. Regenhardt, Mark R. Etherton, Kathleen L. Donahue, Marco Nardin, Steven J. T. Mocking, Elissa C. McIntosh, John Attia, John Attia, Oscar R. Benavente, John W. Cole, Amanda Donatti, Christoph J. Griessenauer, Christoph J. Griessenauer, Laura Heitsch, Laura Heitsch, Lukas Holmegaard, Katarina Jood, Jordi Jimenez-Conde, Jaume Roquer, Steven J. Kittner, Robin Lemmens, Robin Lemmens, Christopher R. Levi, Christopher R. Levi, Caitrin W. McDonough, James F. Meschia, Chia-Ling Phuah, Arndt Rolfs, Stefan Ropele, Jonathan Rosand, Jonathan Rosand, Jonathan Rosand, Tatjana Rundek, Ralph L. Sacco, Reinhold Schmidt, Christian Enzinger, Pankaj Sharma, Pankaj Sharma, Agnieszka Slowik, Alessandro Sousa, Tara M. Stanne, Daniel Strbian, Turgut Tatlisumak, Turgut Tatlisumak, Vincent Thijs, Vincent Thijs, Achala Vagal, Johan Wasselius, Johan Wasselius, Daniel Woo, Ramin Zand, Patrick F. McArdle, Bradford B. Worrall, Ona Wu, Christina Jern, Arne G. Lindgren, Arne G. Lindgren, Jane Maguire, Liisa Tomppo, Polina Golland, Natalia S. Rost, The MRI-GENIE and GISCOME Investigators and the International Stroke Genetics Consortium, Sungmin Hong, Anne-Katrin Giese, Markus D. Schirmer, Anna K. Bonkhoff, Martin Bretzner, Pamela Rist, Adrian V. Dalca, Robert W. Regenhardt, Mark R. Etherton, Kathleen L. Donahue, Marco Nardin, Steven J. T. Mocking, Elissa C. McIntosh, John Attia, Oscar R. Benavente, John W. Cole, Amanda Donatti, Christoph J. Griessenauer, Laura Heitsch, Lukas Holmegaard, Katarina Jood, Jordi Jimenez-Conde, Jaume Roquer, Steven J. Kittner, Robin Lemmens, Christopher R. Levi, Caitrin W. McDonough, James F. Meschia, Chia-Ling Phuah, Arndt Rolfs, Stefan Ropele, Jonathan Rosand, Tatjana Rundek, Ralph L. Sacco, Reinhold Schmidt, Christian Enzinger, Pankaj Sharma, Agnieszka Slowik, Alessandro Sousa, Tara M. Stanne, Daniel Strbian, Turgut Tatlisumak, Vincent Thijs, Achala Vagal, Johan Wasselius, Daniel Woo, Ramin Zand, Patrick F. McArdle, Bradford B. Worrall, Ona Wu, Christina Jern, Arne G. Lindgren, Jane Maguire, Liisa Tomppo, Polina Golland, Natalia S. Rost
Published 2021-09-01