Improved inference of chromosome conformation from images of labeled loci [version 3; peer review: 2 approved]

by Brian C. Ross, James C. Costello
Published 2019-03-01

Androgen Receptor Signaling in Prostate Cancer Genomic Subtypes

by Lauren K. Jillson, Gabriel A. Yette, Teemu D. Laajala, Wayne D. Tilley, James C. Costello, Scott D. Cramer
Published 2021-06-01

Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes

by Josh Lewis Stern, Richard D. Paucek, Franklin W. Huang, Mahmoud Ghandi, Ronald Nwumeh, James C. Costello, Thomas R. Cech
Published 2020-05-01

Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes

by Josh Lewis Stern, Richard D. Paucek, Franklin W. Huang, Mahmoud Ghandi, Ronald Nwumeh, James C. Costello, Thomas R. Cech
Published 2017-12-01

KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1‐driven and independent disease‐promoting gene expression in fusion‐positive Rhabdomyosarcoma

by Lays M. Sobral, Hannah M. Hicks, Janet K. Parrish, Tyler S. McCann, Joseph Hsieh, Andrew Goodspeed, James C. Costello, Joshua C. Black, Paul Jedlicka
Published 2020-10-01

CPT1A Over-Expression Increases Reactive Oxygen Species in the Mitochondria and Promotes Antioxidant Defenses in Prostate Cancer

by Molishree Joshi, Jihye Kim, Angelo D’Alessandro, Emily Monk, Kimberley Bruce, Hanan Elajaili, Eva Nozik-Grayck, Andrew Goodspeed, James C. Costello, Isabel R. Schlaepfer
Published 2020-11-01

Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase

by Forest H. Andrews, Qiong Tong, Kelly D. Sullivan, Evan M. Cornett, Yi Zhang, Muzaffar Ali, JaeWoo Ahn, Ahway Pandey, Angela H. Guo, Brian D. Strahl, James C. Costello, Joaquin M. Espinosa, Scott B. Rothbart, Tatiana G. Kutateladze
Published 2016-09-01

Crowdsourcing assessment of maternal blood multi-omics for predicting gestational age and preterm birth

by Adi L. Tarca, Bálint Ármin Pataki, Roberto Romero, Marina Sirota, Yuanfang Guan, Rintu Kutum, Nardhy Gomez-Lopez, Bogdan Done, Gaurav Bhatti, Thomas Yu, Gaia Andreoletti, Tinnakorn Chaiworapongsa, Sonia S. Hassan, Chaur-Dong Hsu, Nima Aghaeepour, Gustavo Stolovitzky, Istvan Csabai, James C. Costello
Published 2021-06-01

DREAMTools: a Python package for scoring collaborative challenges [version 2; referees: 1 approved, 2 approved with reservations]

by Thomas Cokelaer, Mukesh Bansal, Christopher Bare, Erhan Bilal, Brian M. Bot, Elias Chaibub Neto, Federica Eduati, Alberto de la Fuente, Mehmet Gönen, Steven M. Hill, Bruce Hoff, Jonathan R. Karr, Robert Küffner, Michael P. Menden, Pablo Meyer, Raquel Norel, Abhishek Pratap, Robert J. Prill, Matthew T. Weirauch, James C. Costello, Gustavo Stolovitzky, Julio Saez-Rodriguez
Published 2016-04-01

Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors

by Rani K. Powers, Rachel Culp-Hill, Michael P. Ludwig, Keith P. Smith, Katherine A. Waugh, Ross Minter, Kathryn D. Tuttle, Hannah C. Lewis, Angela L. Rachubinski, Ross E. Granrath, María Carmona-Iragui, Rebecca B. Wilkerson, Darcy E. Kahn, Molishree Joshi, Alberto Lleó, Rafael Blesa, Juan Fortea, Angelo D’Alessandro, James C. Costello, Kelly D. Sullivan, Joaquin M. Espinosa
Published 2019-10-01