UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication.

by Peng-Nien Huang, Jia-Rong Jheng, Jamie J Arnold, Jen-Ren Wang, Craig E Cameron, Shin-Ru Shih
Published 2017-05-01

Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds.

by Laura I Levi, Nina F Gnädig, Stéphanie Beaucourt, Malia J McPherson, Bruno Baron, Jamie J Arnold, Marco Vignuzzi
Published 2010-10-01

Nucleobase but not Sugar Fidelity is Maintained in the Sabin I RNA-Dependent RNA Polymerase

by Xinran Liu, Derek M. Musser, Cheri A. Lee, Xiaorong Yang, Jamie J. Arnold, Craig E. Cameron, David D. Boehr
Published 2015-10-01

A speed-fidelity trade-off determines the mutation rate and virulence of an RNA virus.

by William J Fitzsimmons, Robert J Woods, John T McCrone, Andrew Woodman, Jamie J Arnold, Madhumita Yennawar, Richard Evans, Craig E Cameron, Adam S Lauring
Published 2018-06-01

Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes.

by Greta A Van Slyke, Jamie J Arnold, Alex J Lugo, Sara B Griesemer, Ibrahim M Moustafa, Laura D Kramer, Craig E Cameron, Alexander T Ciota
Published 2015-06-01

Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides.

by Hyung S Oh, Sravani Banerjee, David Aponte-Diaz, Suresh D Sharma, Jason Aligo, Maria F Lodeiro, Gang Ning, Rajni Sharma, Jamie J Arnold, Craig E Cameron
Published 2018-04-01

Single-Cell Virology: On-Chip Investigation of Viral Infection Dynamics

by Feng Guo, Sixing Li, Mehmet Umut Caglar, Zhangming Mao, Wu Liu, Andrew Woodman, Jamie J. Arnold, Claus O. Wilke, Tony Jun Huang, Craig E. Cameron
Published 2017-11-01

Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers

by David Dulin, Jamie J. Arnold, Theo van Laar, Hyung-Suk Oh, Cheri Lee, Angela L. Perkins, Daniel A. Harki, Martin Depken, Craig E. Cameron, Nynke H. Dekker
Published 2017-10-01

Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter

by Akira Uchida, Divakaran Murugesapillai, Markus Kastner, Yao Wang, Maria F Lodeiro, Shaan Prabhakar, Guinevere V Oliver, Jamie J Arnold, L James Maher III, Mark C Williams, Craig E Cameron
Published 2017-07-01

Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides.

by Jamie J Arnold, Suresh D Sharma, Joy Y Feng, Adrian S Ray, Eric D Smidansky, Maria L Kireeva, Aesop Cho, Jason Perry, Jennifer E Vela, Yeojin Park, Yili Xu, Yang Tian, Darius Babusis, Ona Barauskus, Blake R Peterson, Averell Gnatt, Mikhail Kashlev, Weidong Zhong, Craig E Cameron
Published 2012-01-01

Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

by Mona Seifert, Subhas C Bera, Pauline van Nies, Robert N Kirchdoerfer, Ashleigh Shannon, Thi-Tuyet-Nhung Le, Xiangzhi Meng, Hongjie Xia, James M Wood, Lawrence D Harris, Flavia S Papini, Jamie J Arnold, Steven Almo, Tyler L Grove, Pei-Yong Shi, Yan Xiang, Bruno Canard, Martin Depken, Craig E Cameron, David Dulin
Published 2021-10-01

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.

by Lonneke van der Linden, Laia Vives-Adrián, Barbara Selisko, Cristina Ferrer-Orta, Xinran Liu, Kjerstin Lanke, Rachel Ulferts, Armando M De Palma, Federica Tanchis, Nesya Goris, David Lefebvre, Kris De Clercq, Pieter Leyssen, Céline Lacroix, Gerhard Pürstinger, Bruno Coutard, Bruno Canard, David D Boehr, Jamie J Arnold, Craig E Cameron, Nuria Verdaguer, Johan Neyts, Frank J M van Kuppeveld
Published 2015-03-01