From Bedside to Bench and back again – Molecular Mechanisms in Acute Liver Failure

by Jan Peter Sowa, Guido eGerken, Ali eCanbay
Published 2014-01-01

Novel algorithm for non-invasive assessment of fibrosis in NAFLD.

by Jan-Peter Sowa, Dominik Heider, Lars Peter Bechmann, Guido Gerken, Daniel Hoffmann, Ali Canbay
Published 2013-01-01

Significance of Simple Steatosis: An Update on the Clinical and Molecular Evidence

by Guillermo Mazzolini, Jan-Peter Sowa, Catalina Atorrasagasti, Özlem Kücükoglu, Wing-Kin Syn, Ali Canbay
Published 2020-11-01

Liver Injury Indicating Fatty Liver but Not Serologic NASH Marker Improves under Metformin Treatment in Polycystic Ovary Syndrome

by Susanne Tan, Nils Vollmar, Sven Benson, Jan-Peter Sowa, Lars P. Bechmann, Guido Gerken, Dagmar Fuhrer, Ali Canbay
Published 2015-01-01

SPARC expression is associated with hepatic injury in rodents and humans with non-alcoholic fatty liver disease

by Guillermo Mazzolini, Catalina Atorrasagasti, Agostina Onorato, Estanislao Peixoto, Martin Schlattjan, Jan-Peter Sowa, Svenja Sydor, Guido Gerken, Ali Canbay
Published 2018-01-01

A PDGFRβ-based score predicts significant liver fibrosis in patients with chronic alcohol abuse, NAFLD and viral liver diseaseResearch in context

by Joeri Lambrecht, Stefaan Verhulst, Inge Mannaerts, Jan-Peter Sowa, Jan Best, Ali Canbay, Hendrik Reynaert, Leo A. van Grunsven
Published 2019-05-01

Liver parameters as part of a non-invasive model for prediction of all-cause mortality after myocardial infarction

by Theodor Baars, Jan-Peter Sowa, Ursula Neumann, Stefanie Hendricks, Mona Jinawy, Julia Kälsch, Guido Gerken, Tienush Rassaf, Dominik Heider, Ali Canbay
Published 2018-05-01

Deficiency of the promyelocytic leukemia protein fosters hepatitis C-associated hepatocarcinogenesis in mice.

by Kerstin Herzer, Anna Carbow, Svenja Sydor, Jan-Peter Sowa, Stefan Biesterfeld, Thomas-Georg Hofmann, Peter-Robert Galle, Guido Gerken, Ali Canbay
Published 2012-01-01

Economic growth leads to increase of obesity and associated hepatocellular carcinoma in developing countries

by G. Seyda Seydel, Ozlem Kucukoglu, Akif Altinbas, O. Oguz Demir, Sezai Yilmaz, Hikmet Akkiz, Emrah Otan, Jan-Peter Sowa, Ali Canbay
Published 2016-09-01

Non-invasive assessment of NAFLD as systemic disease-A machine learning perspective.

by Ali Canbay, Julia Kälsch, Ursula Neumann, Monika Rau, Simon Hohenester, Hideo A Baba, Christian Rust, Andreas Geier, Dominik Heider, Jan-Peter Sowa
Published 2019-01-01

Etiology, outcome and prognostic factors of childhood acute liver failure in a German Single Center

by Simone Kathemann, Lars P. Bechmann, Jan-Peter Sowa, Paul Manka, Alexander Dechêne, Patrick Gerner, Elke Lainka, Peter F. Hoyer, Ariel E. Feldstein, Ali Canbay
Published 2015-09-01

Mycophenolic acid induces apoptosis of hepatic stellate cells in an in vitro model of HCV

by Jan Best, Andreas Zahn, Anja Beilfuß, Svenja Sydor, Christian Fingas, Jan-Peter Sowa, Olympia Anastasiou, Vito Cicinnati, Guido Gerken, Ali Canbay, Lars P. Bechmann
Published 2015-05-01

Onset of heart failure determines the hepatic cell death pattern

by Kerstin Herzer, Guntje Kneiseler, Lars Peter Bechmann, Felix Post, Martin Schlattjan, Jan-Peter Sowa, Till Neumann, Günter Marggraf, Raimund Erbel, Guido Gerken, Ali Canbay, Christoph Jochum
Published 2011-04-01

Non-invasive separation of alcoholic and non-alcoholic liver disease with predictive modeling.

by Jan-Peter Sowa, Özgür Atmaca, Alisan Kahraman, Martin Schlattjan, Marion Lindner, Svenja Sydor, Norbert Scherbaum, Karoline Lackner, Guido Gerken, Dominik Heider, Gavin E Arteel, Yesim Erim, Ali Canbay
Published 2014-01-01

Higher Thyroid-Stimulating Hormone, Triiodothyronine and Thyroxine Values Are Associated with Better Outcome in Acute Liver Failure.

by Olympia Anastasiou, Svenja Sydor, Jan-Peter Sowa, Paul Manka, Antonios Katsounas, Wing-Kin Syn, Dagmar Führer, Robert K Gieseler, Lars P Bechmann, Guido Gerken, Lars C Moeller, Ali Canbay
Published 2015-01-01

Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis

by Svenja Sydor, Jan-Peter Sowa, Dominik A. Megger, Martin Schlattjan, Sami Jafoui, Lena Wingerter, Alexander Carpinteiro, Hideo A. Baba, Lars P. Bechmann, Barbara Sitek, Guido Gerken, Erich Gulbins, Ali Canbay
Published 2017-05-01

GALAD Score Detects Early-Stage Hepatocellular Carcinoma in a European Cohort of Chronic Hepatitis B and C Patients

by Clemens Schotten, Bastian Ostertag, Jan-Peter Sowa, Paul Manka, Lars P. Bechmann, Gudrun Hilgard, Claudio Marquardt, Marc Wichert, Hidenori Toyoda, Christian M. Lange, Ali Canbay, Philip Johnson, Heiner Wedemeyer, Jan Best
Published 2021-07-01

Macrophage Depletion Attenuates Extracellular Matrix Deposition and Ductular Reaction in a Mouse Model of Chronic Cholangiopathies.

by Jan Best, Stefaan Verhulst, Wing-Kin Syn, Kimberly Lagaisse, Noemi van Hul, Femke Heindryckx, Jan-Peter Sowa, Liesbeth Peeters, Hans Van Vlierberghe, Isabelle A Leclercq, Ali Canbay, Laurent Dollé, Leo A van Grunsven
Published 2016-01-01

Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury

by Svenja Sydor, Paul Manka, Jan Best, Sami Jafoui, Jan-Peter Sowa, Miguel Eugenio Zoubek, Virginia Hernandez-Gea, Francisco Javier Cubero, Julia Kälsch, Diana Vetter, Maria Isabel Fiel, Yujin Hoshida, C. Billie Bian, Leonard J. Nelson, Han Moshage, Klaas Nico Faber, Andreas Paul, Hideo A. Baba, Guido Gerken, Scott L. Friedman, Ali Canbay, Lars P. Bechmann
Published 2017-08-01