Oxygen Sensing and Viral Replication: Implications for Tropism and Pathogenesis

by Peter Jianrui Liu, Peter Balfe, Jane A McKeating, Mirjam Schilling
Published 2020-10-01

Rituximab treatment in hepatitis C infection: an in vitro model to study the impact of B cell depletion on virus infectivity.

by Zania Stamataki, Samantha Tilakaratne, David H Adams, Jane A McKeating
Published 2011-01-01

Daytime variation in hepatitis C virus replication kinetics following liver transplant [version 2; referees: 4 approved, 1 approved with reservations]

by Xiaodong Zhuang, Alvina G. Lai, Jane A. McKeating, Ian Rowe, Peter Balfe
Published 2018-09-01

Daytime variation in hepatitis C virus replication kinetics following liver transplant [version 1; referees: 2 approved]

by Xiaodong Zhuang, Alvina G. Lai, Jane A. McKeating, Ian Rowe, Peter Balfe
Published 2018-08-01

A Role for CD81 and Hepatitis C Virus in Hepatoma Mobility

by Claire L. Brimacombe, Garrick K. Wilson, Stefan G. Hübscher, Jane A. McKeating, Michelle J. Farquhar
Published 2014-03-01

N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection.

by Monique D Appelman, Anindita Chakraborty, Ulrike Protzer, Jane A McKeating, Stan F J van de Graaf
Published 2017-01-01

Glucose and glutamine availability regulate HepG2 transcriptional responses to low oxygen [version 1; referees: 2 approved]

by Alvina G. Lai, Donall Forde, Wai Hoong Chang, Fang Yuan, Xiaodong Zhuang, Claudia Orbegozo Rubio, Chun-Xiao Song, Jane A. McKeating
Published 2018-09-01

A new panel of epitope mapped monoclonal antibodies recognising the prototypical tetraspanin CD81 [version 1; referees: 1 approved, 2 approved with reservations]

by Joe Grove, Ke Hu, Michelle J. Farquhar, Margaret Goodall, Lucas Walker, Mohammed Jamshad, Heidi E. Drummer, Roslyn M. Bill, Peter Balfe, Jane A. McKeating
Published 2017-09-01

Accurate targeted long-read DNA methylation and hydroxymethylation sequencing with TAPS

by Yibin Liu, Jingfei Cheng, Paulina Siejka-Zielińska, Carika Weldon, Hannah Roberts, Maria Lopopolo, Andrea Magri, Valentina D’Arienzo, James M. Harris, Jane A. McKeating, Chun-Xiao Song
Published 2020-03-01

Production, purification and characterization of recombinant, full-length human claudin-1.

by Nicklas Bonander, Mohammed Jamshad, Dominik Oberthür, Michelle Clare, James Barwell, Ke Hu, Michelle J Farquhar, Zania Stamataki, Helen J Harris, Karsten Dierks, Timothy R Dafforn, Christian Betzel, Jane A McKeating, Roslyn M Bill
Published 2013-01-01

A Comprehensive Analysis of the Impact of HIV on HCV Immune Responses and Its Association with Liver Disease Progression in a Unique Plasma Donor Cohort.

by Yong-Hong Zhang, Yan Zhao, Ushani S Rajapaksa, Tessa M Lawrence, Yan-Chun Peng, Jinghua Liu, Keyi Xu, Ke Hu, Ling Qin, Ning Liu, Huanqin Sun, Hui-Ping Yan, Emmanouela Repapi, Sarah Rowland-Jones, Robert Thimme, Jane A McKeating, Tao Dong
Published 2016-01-01

Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes

by Eloi R. Verrier, Che C. Colpitts, Charlotte Bach, Laura Heydmann, Laetitia Zona, Fei Xiao, Christine Thumann, Emilie Crouchet, Raphaël Gaudin, Camille Sureau, François-Loïc Cosset, Jane A. McKeating, Patrick Pessaux, Yujin Hoshida, Catherine Schuster, Mirjam B. Zeisel, Thomas F. Baumert
Published 2016-10-01

Circadian control of hepatitis B virus replication

by Xiaodong Zhuang, Donall Forde, Senko Tsukuda, Valentina D’Arienzo, Laurent Mailly, James M. Harris, Peter A. C. Wing, Helene Borrmann, Mirjam Schilling, Andrea Magri, Claudia Orbegozo Rubio, Robert J. Maidstone, Mudassar Iqbal, Miguel Garzon, Rosalba Minisini, Mario Pirisi, Sam Butterworth, Peter Balfe, David W. Ray, Koichi Watashi, Thomas F. Baumert, Jane A. McKeating
Published 2021-03-01

Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint

by Nathalie M. Schmidt, Peter A. C. Wing, Mariana O. Diniz, Laura J. Pallett, Leo Swadling, James M. Harris, Alice R. Burton, Anna Jeffery-Smith, Nekisa Zakeri, Oliver E. Amin, Stephanie Kucykowicz, Mirjam H. Heemskerk, Brian Davidson, Tim Meyer, Joe Grove, Hans J. Stauss, Ines Pineda-Torra, Clare Jolly, Elizabeth C. Jury, Jane A. McKeating, Mala K. Maini
Published 2021-05-01

The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication

by Xiaodong Zhuang, Andrea Magri, Michelle Hill, Alvina G. Lai, Abhinav Kumar, Srinivasa Bhargav Rambhatla, Claire L. Donald, Andrea F. Lopez-Clavijo, Simon Rudge, Katherine Pinnick, Wai Hoong Chang, Peter A. C. Wing, Ryan Brown, Ximing Qin, Peter Simmonds, Thomas F. Baumert, David Ray, Andrew Loudon, Peter Balfe, Michael Wakelam, Sam Butterworth, Alain Kohl, Catherine L. Jopling, Nicole Zitzmann, Jane A. McKeating
Published 2019-01-01

Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment

by Hirofumi Ohashi, Koichi Watashi, Wakana Saso, Kaho Shionoya, Shoya Iwanami, Takatsugu Hirokawa, Tsuyoshi Shirai, Shigehiko Kanaya, Yusuke Ito, Kwang Su Kim, Takao Nomura, Tateki Suzuki, Kazane Nishioka, Shuji Ando, Keisuke Ejima, Yoshiki Koizumi, Tomohiro Tanaka, Shin Aoki, Kouji Kuramochi, Tadaki Suzuki, Takao Hashiguchi, Katsumi Maenaka, Tetsuro Matano, Masamichi Muramatsu, Masayuki Saijo, Kazuyuki Aihara, Shingo Iwami, Makoto Takeda, Jane A. McKeating, Takaji Wakita
Published 2021-04-01

Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells

by Peter A.C. Wing, Thomas P. Keeley, Xiaodong Zhuang, Jeffrey Y. Lee, Maria Prange-Barczynska, Senko Tsukuda, Sophie B. Morgan, Adam C. Harding, Isobel L.A. Argles, Samvid Kurlekar, Marko Noerenberg, Craig P. Thompson, Kuan-Ying A. Huang, Peter Balfe, Koichi Watashi, Alfredo Castello, Timothy S.C. Hinks, William James, Peter J. Ratcliffe, Ilan Davis, Emma J. Hodson, Tammie Bishop, Jane A. McKeating
Published 2021-04-01

The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells

by Xiaodong Zhuang, Senko Tsukuda, Florian Wrensch, Peter A.C. Wing, Mirjam Schilling, James M. Harris, Helene Borrmann, Sophie B. Morgan, Jennifer L. Cane, Laurent Mailly, Nazia Thakur, Carina Conceicao, Harshmeena Sanghani, Laura Heydmann, Charlotte Bach, Anna Ashton, Steven Walsh, Tiong Kit Tan, Lisa Schimanski, Kuan-Ying A. Huang, Catherine Schuster, Koichi Watashi, Timothy S.C. Hinks, Aarti Jagannath, Sridhar R. Vausdevan, Dalan Bailey, Thomas F. Baumert, Jane A. McKeating
Published 2021-10-01