A race between tumor immunoescape and genome maintenance selects for optimum levels of (epi)genetic instability.

by Shingo Iwami, Hiroshi Haeno, Franziska Michor
Published 2012-01-01

Paradox of vaccination: is vaccination really effective against avian flu epidemics?

by Shingo Iwami, Takafumi Suzuki, Yasuhiro Takeuchi
Published 2009-01-01

Mefloquine, a Potent Anti-severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Drug as an Entry Inhibitor in vitro

by Kaho Shionoya, Kaho Shionoya, Masako Yamasaki, Masako Yamasaki, Shoya Iwanami, Shoya Iwanami, Yusuke Ito, Shuetsu Fukushi, Hirofumi Ohashi, Hirofumi Ohashi, Wakana Saso, Wakana Saso, Wakana Saso, Tomohiro Tanaka, Shin Aoki, Kouji Kuramochi, Shingo Iwami, Shingo Iwami, Shingo Iwami, Shingo Iwami, Shingo Iwami, Shingo Iwami, Shingo Iwami, Yoshimasa Takahashi, Yoshimasa Takahashi, Tadaki Suzuki, Masamichi Muramatsu, Makoto Takeda, Takaji Wakita, Koichi Watashi, Koichi Watashi, Koichi Watashi, Koichi Watashi, Koichi Watashi
Published 2021-04-01

Modeling the efficiency of filovirus entry into cells in vitro: Effects of SNP mutations in the receptor molecule.

by Kwang Su Kim, Tatsunari Kondoh, Yusuke Asai, Ayato Takada, Shingo Iwami
Published 2020-09-01

Direct Evidence of Abortive Lytic Infection-Mediated Establishment of Epstein-Barr Virus Latency During B-Cell Infection

by Tomoki Inagaki, Yoshitaka Sato, Yoshitaka Sato, Jumpei Ito, Mitsuaki Takaki, Yusuke Okuno, Masahiro Yaguchi, H. M. Abdullah Al Masud, H. M. Abdullah Al Masud, Takahiro Watanabe, Kei Sato, Shingo Iwami, Shingo Iwami, Shingo Iwami, Takayuki Murata, Takayuki Murata, Hiroshi Kimura
Published 2021-01-01

A highly pathogenic simian/human immunodeficiency virus effectively produces infectious virions compared with a less pathogenic virus in cell culture

by Shoya Iwanami, Yusuke Kakizoe, Satoru Morita, Tomoyuki Miura, Shinji Nakaoka, Shingo Iwami
Published 2017-04-01

Correction to: Required concentration index quantifies effective drug combinations against hepatitis C virus infection

by Yusuke Kakizoe, Yoshiki Koizumi, Yukino Ikoma, Hirofumi Ohashi, Takaji Wakita, Shingo Iwami, Koichi Watashi
Published 2021-01-01

Required concentration index quantifies effective drug combinations against hepatitis C virus infection

by Yusuke Kakizoe, Yoshiki Koizumi, Yukino Ikoma, Hirofumi Ohashi, Takaji Wakita, Shingo Iwami, Koichi Watashi
Published 2021-01-01

Number of infection events per cell during HIV-1 cell-free infection

by Yusuke Ito, Azaria Remion, Alexandra Tauzin, Keisuke Ejima, Shinji Nakaoka, Yoh Iwasa, Shingo Iwami, Fabrizio Mammano
Published 2017-07-01

HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo.

by Kei Sato, Naoko Misawa, Shingo Iwami, Yorifumi Satou, Masao Matsuoka, Yukihito Ishizaka, Mamoru Ito, Kazuyuki Aihara, Dong Sung An, Yoshio Koyanagi
Published 2013-01-01

Cell-to-cell infection by HIV contributes over half of virus infection

by Shingo Iwami, Junko S Takeuchi, Shinji Nakaoka, Fabrizio Mammano, François Clavel, Hisashi Inaba, Tomoko Kobayashi, Naoko Misawa, Kazuyuki Aihara, Yoshio Koyanagi, Kei Sato
Published 2015-10-01

Should a viral genome stay in the host cell or leave? A quantitative dynamics study of how hepatitis C virus deals with this dilemma.

by Shoya Iwanami, Kosaku Kitagawa, Hirofumi Ohashi, Yusuke Asai, Kaho Shionoya, Wakana Saso, Kazane Nishioka, Hisashi Inaba, Shinji Nakaoka, Takaji Wakita, Odo Diekmann, Shingo Iwami, Koichi Watashi
Published 2020-07-01

Estimation of the incubation period of COVID-19 using viral load data

by Keisuke Ejima, Kwang Su Kim, Christina Ludema, Ana I. Bento, Shoya Iwanami, Yasuhisa Fujita, Hirofumi Ohashi, Yoshiki Koizumi, Koichi Watashi, Kazuyuki Aihara, Hiroshi Nishiura, Shingo Iwami
Published 2021-06-01

Revisiting the guidelines for ending isolation for COVID-19 patients

by Yong Dam Jeong, Keisuke Ejima, Kwang Su Kim, Shoya Iwanami, Ana I Bento, Yasuhisa Fujita, Il Hyo Jung, Kazuyuki Aihara, Koichi Watashi, Taiga Miyazaki, Takaji Wakita, Shingo Iwami, Marco Ajelli
Published 2021-07-01

A quantitative model used to compare within-host SARS-CoV-2, MERS-CoV, and SARS-CoV dynamics provides insights into the pathogenesis and treatment of SARS-CoV-2.

by Kwang Su Kim, Keisuke Ejima, Shoya Iwanami, Yasuhisa Fujita, Hirofumi Ohashi, Yoshiki Koizumi, Yusuke Asai, Shinji Nakaoka, Koichi Watashi, Kazuyuki Aihara, Robin N Thompson, Ruian Ke, Alan S Perelson, Shingo Iwami
Published 2021-03-01

HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation.

by Yusuke Nakano, Naoko Misawa, Guillermo Juarez-Fernandez, Miyu Moriwaki, Shinji Nakaoka, Takaaki Funo, Eri Yamada, Andrew Soper, Rokusuke Yoshikawa, Diako Ebrahimi, Yuuya Tachiki, Shingo Iwami, Reuben S Harris, Yoshio Koyanagi, Kei Sato
Published 2017-05-01

APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model.

by Kei Sato, Junko S Takeuchi, Naoko Misawa, Taisuke Izumi, Tomoko Kobayashi, Yuichi Kimura, Shingo Iwami, Akifumi Takaori-Kondo, Wei-Shau Hu, Kazuyuki Aihara, Mamoru Ito, Dong Sung An, Vinay K Pathak, Yoshio Koyanagi
Published 2014-10-01

Correction: HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation.

by Yusuke Nakano, Naoko Misawa, Guillermo Juarez-Fernandez, Miyu Moriwaki, Shinji Nakaoka, Takaaki Funo, Eri Yamada, Andrew Soper, Rokusuke Yoshikawa, Diako Ebrahimi, Yuuya Tachiki, Shingo Iwami, Reuben S Harris, Yoshio Koyanagi, Kei Sato
Published 2017-09-01

Detection of significant antiviral drug effects on COVID-19 with reasonable sample sizes in randomized controlled trials: A modeling study.

by Shoya Iwanami, Keisuke Ejima, Kwang Su Kim, Koji Noshita, Yasuhisa Fujita, Taiga Miyazaki, Shigeru Kohno, Yoshitsugu Miyazaki, Shimpei Morimoto, Shinji Nakaoka, Yoshiki Koizumi, Yusuke Asai, Kazuyuki Aihara, Koichi Watashi, Robin N Thompson, Kenji Shibuya, Katsuhito Fujiu, Alan S Perelson, Shingo Iwami, Takaji Wakita
Published 2021-07-01

Efficacy and safety of nelfinavir in asymptomatic and mild COVID-19 patients: a structured summary of a study protocol for a multicenter, randomized controlled trial

by Naoki Hosogaya, Taiga Miyazaki, Yuri Fukushige, Sachiko Takemori, Shinpei Morimoto, Hiroshi Yamamoto, Makoto Hori, Tomoya Kurokawa, Yohei Kawasaki, Michiko Hanawa, Yasuhisa Fujii, Hideki Hanaoka, Shingo Iwami, Koichi Watashi, Satoshi Yamagoe, Yoshitsugu Miyazaki, Takaji Wakita, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae, Shigeru Kohno, Nelfinavir Study Group
Published 2021-04-01