Impacts of Humanized Mouse Models on the Investigation of HIV-1 Infection: Illuminating the Roles of Viral Accessory Proteins in Vivo

by Eri Yamada, Rokusuke Yoshikawa, Yusuke Nakano, Naoko Misawa, Yoshio Koyanagi, Kei Sato
Published 2015-03-01

A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector.

by Hirotaka Ebina, Yuka Kanemura, Naoko Misawa, Tetsushi Sakuma, Tomoko Kobayashi, Takashi Yamamoto, Yoshio Koyanagi
Published 2015-01-01

HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo.

by Kei Sato, Naoko Misawa, Shingo Iwami, Yorifumi Satou, Masao Matsuoka, Yukihito Ishizaka, Mamoru Ito, Kazuyuki Aihara, Dong Sung An, Yoshio Koyanagi
Published 2013-01-01

Cell-to-cell infection by HIV contributes over half of virus infection

by Shingo Iwami, Junko S Takeuchi, Shinji Nakaoka, Fabrizio Mammano, François Clavel, Hisashi Inaba, Tomoko Kobayashi, Naoko Misawa, Kazuyuki Aihara, Yoshio Koyanagi, Kei Sato
Published 2015-10-01

Dynamics and mechanisms of clonal expansion of HIV-1-infected cells in a humanized mouse model

by Yorifumi Satou, Hiroo Katsuya, Asami Fukuda, Naoko Misawa, Jumpei Ito, Yoshikazu Uchiyama, Paola Miyazato, Saiful Islam, Ariberto Fassati, Anat Melamed, Charles R. M. Bangham, Yoshio Koyanagi, Kei Sato
Published 2017-07-01

HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation.

by Yusuke Nakano, Naoko Misawa, Guillermo Juarez-Fernandez, Miyu Moriwaki, Shinji Nakaoka, Takaaki Funo, Eri Yamada, Andrew Soper, Rokusuke Yoshikawa, Diako Ebrahimi, Yuuya Tachiki, Shingo Iwami, Reuben S Harris, Yoshio Koyanagi, Kei Sato
Published 2017-05-01

APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model.

by Kei Sato, Junko S Takeuchi, Naoko Misawa, Taisuke Izumi, Tomoko Kobayashi, Yuichi Kimura, Shingo Iwami, Akifumi Takaori-Kondo, Wei-Shau Hu, Kazuyuki Aihara, Mamoru Ito, Dong Sung An, Vinay K Pathak, Yoshio Koyanagi
Published 2014-10-01

Correction: HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation.

by Yusuke Nakano, Naoko Misawa, Guillermo Juarez-Fernandez, Miyu Moriwaki, Shinji Nakaoka, Takaaki Funo, Eri Yamada, Andrew Soper, Rokusuke Yoshikawa, Diako Ebrahimi, Yuuya Tachiki, Shingo Iwami, Reuben S Harris, Yoshio Koyanagi, Kei Sato
Published 2017-09-01

A role for gorilla APOBEC3G in shaping lentivirus evolution including transmission to humans.

by Yusuke Nakano, Keisuke Yamamoto, Mahoko Takahashi Ueda, Andrew Soper, Yoriyuki Konno, Izumi Kimura, Keiya Uriu, Ryuichi Kumata, Hirofumi Aso, Naoko Misawa, Shumpei Nagaoka, Soma Shimizu, Keito Mitsumune, Yusuke Kosugi, Guillermo Juarez-Fernandez, Jumpei Ito, So Nakagawa, Terumasa Ikeda, Yoshio Koyanagi, Reuben S Harris, Kei Sato
Published 2020-09-01