Gene specific therapies – the next therapeutic milestone in neurology

by David Brenner, Albert C. Ludolph, Jochen H. Weishaupt
Published 2020-09-01

Commentary: Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity

by Axel Freischmidt, Axel Freischmidt, David Brenner, David Brenner, Albert C. Ludolph, Albert C. Ludolph, Peter M. Andersen, Jochen H. Weishaupt, Jochen H. Weishaupt
Published 2020-09-01

Cell-Penetrating Fragments of the Cdk5 Regulatory Subunit Are Protective in Models of Neurodegeneration

by Jan Liman, Jochen H. Weishaupt, Mathias Bähr, Gunnar P.H. Dietz
Published 2010-04-01

In vivo histopathological staging in C9orf72-associated ALS: A tract of interest DTI study

by Hans-Peter Müller, Kelly Del Tredici, Dorothée Lulé, Kathrin Müller, Jochen H. Weishaupt, Albert C. Ludolph, Jan Kassubek
Published 2020-01-01

Proteasome impairment by α-synuclein.

by Lisa Zondler, Marcus Kostka, Patrick Garidel, Udo Heinzelmann, Bastian Hengerer, Benjamin Mayer, Jochen H Weishaupt, Frank Gillardon, Karin M Danzer
Published 2017-01-01

Influence of methylene blue on microglia-induced inflammation and motor neuron degeneration in the SOD1(G93A) model for ALS.

by Payam Dibaj, Jana Zschüntzsch, Heinz Steffens, Jörg Scheffel, Bettina Göricke, Jochen H Weishaupt, Karim Le Meur, Frank Kirchhoff, Uwe-Karsten Hanisch, Eike D Schomburg, Clemens Neusch
Published 2012-01-01

Interleukin-1 Antagonist Anakinra in Amyotrophic Lateral Sclerosis--A Pilot Study.

by André Maier, Nikolaus Deigendesch, Kathrin Müller, Jochen H Weishaupt, Alexander Krannich, Robert Röhle, Felix Meissner, Kaaweh Molawi, Christoph Münch, Teresa Holm, Robert Meyer, Thomas Meyer, Arturo Zychlinsky
Published 2015-01-01

The TGF-β System As a Potential Pathogenic Player in Disease Modulation of Amyotrophic Lateral Sclerosis

by Sebastian Peters, Eva Zitzelsperger, Sabrina Kuespert, Sabine Iberl, Rosmarie Heydn, Siw Johannesen, Susanne Petri, Ludwig Aigner, Dietmar R. Thal, Andreas Hermann, Jochen H. Weishaupt, Tim-Henrik Bruun, Ulrich Bogdahn
Published 2017-12-01

Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the...

by Hans-Peter Müller, David Brenner, Francesco Roselli, Diana Wiesner, Alireza Abaei, Martin Gorges, Karin M. Danzer, Albert C. Ludolph, William Tsao, Philip C. Wong, Volker Rasche, Jochen H. Weishaupt, Jan Kassubek
Published 2019-08-01

Protein Binding Partners of Dysregulated miRNAs in Parkinson’s Disease Serum

by Wolfgang P. Ruf, Axel Freischmidt, Veselin Grozdanov, Valerie Roth, Sarah J. Brockmann, Brit Mollenhauer, Dorothea Martin, Bernhard Haslinger, Katrin Fundel-Clemens, Markus Otto, Christine von Arnim, Karlheinz Holzmann, Albert C. Ludolph, Jochen H. Weishaupt, Karin M. Danzer
Published 2021-04-01

Reduction of ephrin-A5 aggravates disease progression in amyotrophic lateral sclerosis

by Laura Rué, Patrick Oeckl, Mieke Timmers, Annette Lenaerts, Jasmijn van der Vos, Silke Smolders, Lindsay Poppe, Antina de Boer, Ludo Van Den Bosch, Philip Van Damme, Jochen H. Weishaupt, Albert C. Ludolph, Markus Otto, Wim Robberecht, Robin Lemmens
Published 2019-07-01

Phenotypes and malignancy risk of different FUS mutations in genetic amyotrophic lateral sclerosis

by Marcel Naumann, Kevin Peikert, Rene Günther, Anneke J. van derKooi, Eleonora Aronica, Annemarie Hübers, Veronique Danel, Philippe Corcia, Francisco Pan‐Montojo, Sebahattin Cirak, Göknur Haliloglu, Albert C. Ludolph, Anand Goswami, Peter M. Andersen, Johannes Prudlo, Florian Wegner, Philip Van Damme, Jochen H. Weishaupt, Andreas Hermann
Published 2019-12-01

In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species

by Martin Kiechle, Bjoern von Einem, Lennart Höfs, Patrizia Voehringer, Veselin Grozdanov, Daniel Markx, Rosanna Parlato, Diana Wiesner, Benjamin Mayer, Olena Sakk, Bernd Baumann, Soeren Lukassen, Birgit Liss, Arif B. Ekici, Albert C. Ludolph, Paul Walther, Boris Ferger, Pamela J. McLean, Björn H. Falkenburger, Jochen H. Weishaupt, Karin M. Danzer
Published 2019-11-01

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation

by Marcel Naumann, Arun Pal, Anand Goswami, Xenia Lojewski, Julia Japtok, Anne Vehlow, Maximilian Naujock, René Günther, Mengmeng Jin, Nancy Stanslowsky, Peter Reinhardt, Jared Sterneckert, Marie Frickenhaus, Francisco Pan-Montojo, Erik Storkebaum, Ina Poser, Axel Freischmidt, Jochen H. Weishaupt, Karlheinz Holzmann, Dirk Troost, Albert C. Ludolph, Tobias M. Boeckers, Stefan Liebau, Susanne Petri, Nils Cordes, Anthony A. Hyman, Florian Wegner, Stephan W. Grill, Joachim Weis, Alexander Storch, Andreas Hermann
Published 2018-01-01