Ten Simple Rules to becoming a principal investigator.

by John S Tregoning, Jason E McDermott
Published 2020-02-01

A Comparison of Red Fluorescent Proteins to Model DNA Vaccine Expression by Whole Animal In Vivo Imaging.

by Ekaterina Kinnear, Lisa J Caproni, John S Tregoning
Published 2015-01-01

Respiratory Viral Infection Alters the Gut Microbiota by Inducing Inappetence

by Helen T. Groves, Sophie L. Higham, Miriam F. Moffatt, Michael J. Cox, John S. Tregoning
Published 2020-02-01

Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis

by Tatyana A. Shelkovnikova, Haiyan An, Lucy Skelt, John S. Tregoning, Ian R. Humphreys, Vladimir L. Buchman
Published 2019-12-01

A "prime-pull" vaccine strategy has a modest effect on local and systemic antibody responses to HIV gp140 in mice.

by John S Tregoning, Viviana Buffa, Anna Oszmiana, Katja Klein, Adam A Walters, Robin J Shattock
Published 2013-01-01

Nasal IgA Provides Protection against Human Influenza Challenge in Volunteers with Low Serum Influenza Antibody Titre

by Victoria M. W. Gould, James N. Francis, Katie J. Anderson, Bertrand Georges, Alethea V. Cope, John S. Tregoning
Published 2017-05-01

Mucosal application of gp140 encoding DNA polyplexes to different tissues results in altered immunological outcomes in mice.

by Jamie F S Mann, Paul F McKay, Samantha Arokiasamy, Reeyeshkumar K Patel, John S Tregoning, Robin J Shattock
Published 2013-01-01

DNA vaccines encoding antigen targeted to MHC class II induce influenza specific CD8+ T cell responses, enabling faster resolution of influenza disease.

by Laura Lambert, Ekaterina Kinnear, Jacqueline McDonald, Gunnveig Grødeland, Bjarne Bogen, Elisabeth Stubsrud, Mona Lindeberg, Agnete Brunsvik Fredriksen, John S Tregoning
Published 2016-08-01

Intramuscular Immunisation with Chlamydial Proteins Induces Chlamydia trachomatis Specific Ocular Antibodies.

by Alexander Badamchi-Zadeh, Paul F McKay, Martin J Holland, Wayne Paes, Andrzej Brzozowski, Charles Lacey, Frank Follmann, John S Tregoning, Robin J Shattock
Published 2015-01-01

The chemokine MIP1alpha/CCL3 determines pathology in primary RSV infection by regulating the balance of T cell populations in the murine lung.

by John S Tregoning, Philippa K Pribul, Alasdair M J Pennycook, Tracy Hussell, Belinda Wang, Nicholas Lukacs, Jurgen Schwarze, Fiona J Culley, Peter J M Openshaw
Published 2010-02-01

Respiratory Disease following Viral Lung Infection Alters the Murine Gut Microbiota

by Helen T. Groves, Leah Cuthbertson, Leah Cuthbertson, Phillip James, Phillip James, Miriam F. Moffatt, Miriam F. Moffatt, Michael J. Cox, Michael J. Cox, John S. Tregoning
Published 2018-02-01

Comparative Metabolomic Sampling of Upper and Lower Airways by Four Different Methods to Identify Biochemicals That May Support Bacterial Growth

by Hugo Farne, Helen T. Groves, Simren K. Gill, Isobel Stokes, Scott McCulloch, Edward Karoly, Maria-Belen Trujillo-Torralbo, Sebastian L. Johnston, Patrick Mallia, John S. Tregoning
Published 2018-12-01

Glucopyranosyl Lipid Adjuvant (GLA), a Synthetic TLR4 agonist, promotes potent systemic and mucosal responses to intranasal immunization with HIVgp140.

by Mauricio A Arias, Griet A Van Roey, John S Tregoning, Magdalini Moutaftsi, Rhea N Coler, Hillarie P Windish, Steven G Reed, Darrick Carter, Robin J Shattock
Published 2012-01-01

Natural Killer Cells Dampen the Pathogenic Features of Recall Responses to Influenza Infection

by Jason P. Mooney, Jason P. Mooney, Tedi Qendro, Marianne Keith, Adrian W. Philbey, Helen T. Groves, John S. Tregoning, Martin R. Goodier, Eleanor M. Riley, Eleanor M. Riley
Published 2020-02-01

Mouse Models of Influenza Infection with Circulating Strains to Test Seasonal Vaccine Efficacy

by Helen T. Groves, Jacqueline U. McDonald, Pinky Langat, Ekaterina Kinnear, Paul Kellam, John McCauley, Joanna Ellis, Catherine Thompson, Ruth Elderfield, Lauren Parker, Wendy Barclay, John S. Tregoning
Published 2018-01-01

A multi-component prime-boost vaccination regimen with a consensus MOMP antigen enhances Chlamydia trachomatis clearance.

by Alexander eBadamchi-Zadeh, Paul F. McKay, Bette T. Korber, Guillermo eBarinaga, Adam A. Walters, Alexandra eNunes, João Paulo Gomes, Frank eFollmann, John S. Tregoning, Robin J. Shattock
Published 2016-04-01

A Single-Stranded Oligonucleotide Inhibits Toll-Like Receptor 3 Activation and Reduces Influenza A (H1N1) Infection

by Candice Poux, Aleksandra Dondalska, Joseph Bergenstråhle, Sandra Pålsson, Vanessa Contreras, Claudia Arasa, Peter Järver, Jan Albert, Jan Albert, David C. Busse, Roger LeGrand, Joakim Lundeberg, John S. Tregoning, Anna-Lena Spetz
Published 2019-09-01

A Simple Screening Approach To Prioritize Genes for Functional Analysis Identifies a Role for Interferon Regulatory Factor 7 in the Control of Respiratory Syncytial Virus Disease

by Jacqueline U. McDonald, Myrsini Kaforou, Simon Clare, Christine Hale, Maria Ivanova, Derek Huntley, Marcus Dorner, Victoria J. Wright, Michael Levin, Federico Martinon-Torres, Jethro A. Herberg, John S. Tregoning, Sergio Baranzini
Published 2016-06-01

The switch between acute and persistent paramyxovirus infection caused by single amino acid substitutions in the RNA polymerase P subunit.

by Dan F Young, Elizabeth B Wignall-Fleming, David C Busse, Matthew J Pickin, Jack Hankinson, Elizabeth M Randall, Amy Tavendale, Andrew J Davison, Douglas Lamont, John S Tregoning, Steve Goodbourn, Richard E Randall
Published 2019-02-01

Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model.

by Aaron R Everitt, Simon Clare, Jacqueline U McDonald, Leanne Kane, Katherine Harcourt, Malika Ahras, Amar Lall, Christine Hale, Angela Rodgers, Douglas B Young, Ashraful Haque, Oliver Billker, John S Tregoning, Gordon Dougan, Paul Kellam
Published 2013-01-01