5-HT2 receptor binding, functional activity and selectivity in N-benzyltryptamines.

by Miguel Toro-Sazo, José Brea, María I Loza, Marta Cimadevila, Bruce K Cassels
Published 2019-01-01

Cognitive Deficit in Schizophrenia: From Etiology to Novel Treatments

by Antón L. Martínez, José Brea, Sara Rico, María Teresa de los Frailes, María Isabel Loza
Published 2021-09-01

Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite shortening.

by Antón L Martínez, José Brea, Mateo Barro, Xavier Monroy, Manuel Merlos, Javier Burgueño, María Isabel Loza
Published 2021-01-01

Fingerprint-Based Machine Learning Approach to Identify Potent and Selective 5-HT2BR Ligands

by Krzysztof Rataj, Ádám Andor Kelemen, José Brea, María Isabel Loza, Andrzej J. Bojarski, György Miklós Keserű
Published 2018-05-01

Congenital and perinatal complications of chikungunya fever: a Latin American experience

by Jaime R. Torres, Luiza H. Falleiros-Arlant, Lourdes Dueñas, Jorge Pleitez-Navarrete, Doris M. Salgado, José Brea-Del Castillo
Published 2016-10-01

Targeting PDE10A GAF Domain with Small Molecules: A Way for Allosteric Modulation with Anti-Inflammatory Effects

by Ana M. García, José Brea, Alejandro González-García, Concepción Pérez, María Isabel Cadavid, María Isabel Loza, Ana Martinez, Carmen Gil
Published 2017-09-01

Epidemiological burden of invasive pneumococcal disease in children and adolescents with predisposing risk factors

by Luiza Helena Falleiros-Arlant, Eitan Naaman Berezin, Maria Luisa Avila-Aguero, Maria Catalina Pirez, Angela Gentile, Vesta Richardson, Jose Brea, Cristina Mariño
Published 2015-09-01

Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases

by Leen Kalash, Cristina Val, Jhonny Azuaje, María I. Loza, Fredrik Svensson, Azedine Zoufir, Lewis Mervin, Graham Ladds, José Brea, Robert Glen, Eddy Sotelo, Andreas Bender
Published 2017-12-01

Modeling ANXA2-overexpressing circulating tumor cells homing and high throughput screening for metastasis impairment in endometrial carcinomas

by Carolina Herrero, Jose Brea, Amparo Pérez-Díaz, Emiliano Cuadrado, Noelia Ferreño, Cristian Pablo Moiola, Eva Colás, Antonio Gil-Moreno, Rafael López-López, María Isabel Loza, Miguel Abal, Lorena Alonso-Alconada
Published 2021-08-01

Promising 2,6,9-Trisubstituted Purine Derivatives for Anticancer Compounds: Synthesis, 3D-QSAR, and Preliminary Biological Assays

by Cristian O. Salas, Ana Maria Zarate, Vladimir Kryštof, Jaime Mella, Mario Faundez, Jose Brea, María Isabel Loza, Ivan Brito, Denisa Hendrychová, Radek Jorda, Alan R. Cabrera, Ricardo A. Tapia, Christian Espinosa-Bustos
Published 2019-12-01

The application of the open pharmacological concepts triple store (open PHACTS) to support drug discovery research.

by Joseline Ratnam, Barbara Zdrazil, Daniela Digles, Emiliano Cuadrado-Rodriguez, Jean-Marc Neefs, Hannah Tipney, Ronald Siebes, Andra Waagmeester, Glyn Bradley, Chau Han Chau, Lars Richter, Jose Brea, Chris T Evelo, Edgar Jacoby, Stefan Senger, Maria Isabel Loza, Gerhard F Ecker, Christine Chichester
Published 2014-01-01

Pharmacology and preclinical validation of a novel anticancer compound targeting PEPCK-M

by Marc Aragó, Juan Moreno-Felici, Sonia Abás, Sergio Rodríguez-Arévalo, Petra Hyroššová, Agnes Figueras, Francesc Viñals, Belén Pérez, Maria I. Loza, Jose Brea, Pedro Latorre, Jose A. Carrodeguas, Pablo M. García-Rovés, Carlos Galdeano, Tiziana Ginex, Francisco J. Luque, Carmen Escolano, Jose C. Perales
Published 2020-01-01

Influenza tetravalent vaccines in national immunization programs for Latin-American countries

by Macías Hernández, Alejandro E., Santos, Fortino Solórzano, Aguilar Velasco, Hugo M., Ávila Agüero, María L., Rubio, Fernando Bazzino, Junqueira Bellei, Nancy C., Bonvehí, Pablo E., Del Castillo, José Brea, Leguizamón, Héctor Castro, Allan Santos Domingues, Carla M., García García, María D.L., Trujillo, Darío Londoño, Lópe, Pío López, De León Rosales, Samuel Ponce, Cervantes Powell, Patricia G., Suárez Ognio, Luis A.N., Ruiz-Palacios y Santos, Guillermo M.
Published 2021

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

by Wesley C Van Voorhis, John H Adams, Roberto Adelfio, Vida Ahyong, Myles H Akabas, Pietro Alano, Aintzane Alday, Yesmalie Alemán Resto, Aishah Alsibaee, Ainhoa Alzualde, Katherine T Andrews, Simon V Avery, Vicky M Avery, Lawrence Ayong, Mark Baker, Stephen Baker, Choukri Ben Mamoun, Sangeeta Bhatia, Quentin Bickle, Lotfi Bounaadja, Tana Bowling, Jürgen Bosch, Lauren E Boucher, Fabrice F Boyom, Jose Brea, Marian Brennan, Audrey Burton, Conor R Caffrey, Grazia Camarda, Manuela Carrasquilla, Dee Carter, Maria Belen Cassera, Ken Chih-Chien Cheng, Worathad Chindaudomsate, Anthony Chubb, Beatrice L Colon, Daisy D Colón-López, Yolanda Corbett, Gregory J Crowther, Noemi Cowan, Sarah D'Alessandro, Na Le Dang, Michael Delves, Joseph L DeRisi, Alan Y Du, Sandra Duffy, Shimaa Abd El-Salam El-Sayed, Michael T Ferdig, José A Fernández Robledo, David A Fidock, Isabelle Florent, Patrick V T Fokou, Ani Galstian, Francisco Javier Gamo, Suzanne Gokool, Ben Gold, Todd Golub, Gregory M Goldgof, Rajarshi Guha, W Armand Guiguemde, Nil Gural, R Kiplin Guy, Michael A E Hansen, Kirsten K Hanson, Andrew Hemphill, Rob Hooft van Huijsduijnen, Takaaki Horii, Paul Horrocks, Tyler B Hughes, Christopher Huston, Ikuo Igarashi, Katrin Ingram-Sieber, Maurice A Itoe, Ajit Jadhav, Amornrat Naranuntarat Jensen, Laran T Jensen, Laran T Jensen, Rays H Y Jiang, Annette Kaiser, Jennifer Keiser, Thomas Ketas, Sebastien Kicka, Sunyoung Kim, Kiaran Kirk, Vidya P Kumar, Dennis E Kyle, Maria Jose Lafuente, Scott Landfear, Nathan Lee, Sukjun Lee, Adele M Lehane, Fengwu Li, David Little, Liqiong Liu, Manuel Llinás, Maria I Loza, Aristea Lubar, Leonardo Lucantoni, Isabelle Lucet, Louis Maes, Dalu Mancama, Nuha R Mansour, Sandra March, Sheena McGowan, Iset Medina Vera, Stephan Meister, Luke Mercer, Jordi Mestres, Alvine N Mfopa, Raj N Misra, Seunghyun Moon, John P Moore, Francielly Morais Rodrigues da Costa, Joachim Müller, Arantza Muriana, Stephen Nakazawa Hewitt, Bakela Nare, Carl Nathan, Nathalie Narraidoo, Sujeevi Nawaratna, Kayode K Ojo, Diana Ortiz, Gordana Panic, George Papadatos, Silvia Parapini, Kailash Patra, Ngoc Pham, Sarah Prats, David M Plouffe, Sally-Ann Poulsen, Anupam Pradhan, Celia Quevedo, Ronald J Quinn, Christopher A Rice, Mohamed Abdo Rizk, Andrea Ruecker, Robert St Onge, Rafaela Salgado Ferreira, Jasmeet Samra, Natalie G Robinett, Ulrich Schlecht, Marjorie Schmitt, Filipe Silva Villela, Francesco Silvestrini, Robert Sinden, Dennis A Smith, Thierry Soldati, Andreas Spitzmüller, Serge Maximilian Stamm, David J Sullivan, William Sullivan, Sundari Suresh, Brian M Suzuki, Yo Suzuki, S Joshua Swamidass, Donatella Taramelli, Lauve R Y Tchokouaha, Anjo Theron, David Thomas, Kathryn F Tonissen, Simon Townson, Abhai K Tripathi, Valentin Trofimov, Kenneth O Udenze, Imran Ullah, Cindy Vallieres, Edgar Vigil, Joseph M Vinetz, Phat Voong Vinh, Hoan Vu, Nao-Aki Watanabe, Kate Weatherby, Pamela M White, Andrew F Wilks, Elizabeth A Winzeler, Edward Wojcik, Melanie Wree, Wesley Wu, Naoaki Yokoyama, Paul H A Zollo, Nada Abla, Benjamin Blasco, Jeremy Burrows, Benoît Laleu, Didier Leroy, Thomas Spangenberg, Timothy Wells, Paul A Willis
Published 2016-07-01