Spiny mice (Acomys) exhibit attenuated hallmarks of aging and rapid cell turnover after UV exposure in the skin epidermis.

by Wesley Wong, Austin Kim, James R Monaghan, Ashley W Seifert, Malcolm Maden, Justin D Crane
Published 2020-01-01

Elevated mitochondrial oxidative stress impairs metabolic adaptations to exercise in skeletal muscle.

by Justin D Crane, Arkan Abadi, Bart P Hettinga, Daniel I Ogborn, Lauren G MacNeil, Gregory R Steinberg, Mark A Tarnopolsky
Published 2013-01-01

Supplementation with α-lipoic acid, CoQ10, and vitamin E augments running performance and mitochondrial function in female mice.

by Arkan Abadi, Justin D Crane, Daniel Ogborn, Bart Hettinga, Mahmood Akhtar, Andrew Stokl, Lauren Macneil, Adeel Safdar, Adeel Safdar, Mark Tarnopolsky
Published 2013-01-01

FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasi...

by Emilio P. Mottillo, Eric M. Desjardins, Andreas M. Fritzen, Vito Z. Zou, Justin D. Crane, Julian M. Yabut, Bente Kiens, Derek M. Erion, Adhiraj Lanba, James G. Granneman, Saswata Talukdar, Gregory R. Steinberg
Published 2017-06-01

Genetic deletion of mast cell serotonin synthesis prevents the development of obesity and insulin resistance

by Julian M. Yabut, Eric M. Desjardins, Eric J. Chan, Emily A. Day, Julie M. Leroux, Bo Wang, Elizabeth D. Crane, Wesley Wong, Katherine M. Morrison, Justin D. Crane, Waliul I. Khan, Gregory R. Steinberg
Published 2020-01-01