Inflammation and Wnt Signaling: Target for Immunomodulatory Therapy?

by Imen Jridi, Kirsten Canté-Barrett, Karin Pike-Overzet, Frank J. T. Staal
Published 2021-02-01

Aberrant Wnt Signaling in Leukemia

by Frank J. T. Staal, Farbod Famili, Laura Garcia Perez, Karin Pike-Overzet
Published 2016-08-01

Ex Vivo Expansion of Hematopoietic Stem Cells for Therapeutic Purposes: Lessons from Development and the Niche

by Parisa Tajer, Karin Pike-Overzet, Sagrario Arias, Menzo Havenga, Frank J.T. Staal
Published 2019-02-01

Preclinical Development of Autologous Hematopoietic Stem Cell-Based Gene Therapy for Immune Deficiencies: A Journey from Mouse Cage to Bed Side

by Laura Garcia-Perez, Anita Ordas, Kirsten Canté-Barrett, Pauline Meij, Karin Pike-Overzet, Arjan Lankester, Frank J. T. Staal
Published 2020-06-01

Combining Mobilizing Agents with Busulfan to Reduce Chemotherapy-Based Conditioning for Hematopoietic Stem Cell Transplantation

by Laura Garcia-Perez, Lieke van Roon, Marco W. Schilham, Arjan C. Lankester, Karin Pike-Overzet, Frank J.T. Staal
Published 2021-04-01

A Novel Branched DNA-Based Flowcytometric Method for Single-Cell Characterization of Gene Therapy Products and Expression of Therapeutic Genes

by Laura Garcia-Perez, Marja C.J.A. van Eggermond, Elisa Maietta, Marie-Louise P. van der Hoorn, Karin Pike-Overzet, Frank J. T. Staal
Published 2021-01-01

Genomic Engineering in Human Hematopoietic Stem Cells: Hype or Hope?

by Stefanie Klaver-Flores, Hidde A. Zittersteijn, Kirsten Canté-Barrett, Arjan Lankester, Rob C. Hoeben, Manuel A. F. V. Gonçalves, Karin Pike-Overzet, Frank J. T. Staal
Published 2021-01-01

The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice

by Geerte Hoeke, P. Padmini S.J. Khedoe, Janna A. van Diepen, Karin Pike-Overzet, Britt van de Ven, Nadia Vazirpanah, Isabel Mol, Pieter S. Hiemstra, Frank J.T. Staal, Rinke Stienstra, Mihai G. Netea, Charles A. Dinarello, Patrick C.N. Rensen, Jimmy F.P. Berbée
Published 2017-08-01

Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID

by Laura Garcia-Perez, Marja van Eggermond, Lieke van Roon, Sandra A. Vloemans, Martijn Cordes, Axel Schambach, Michael Rothe, Dagmar Berghuis, Chantal Lagresle-Peyrou, Marina Cavazzana, Fang Zhang, Adrian J. Thrasher, Daniela Salvatori, Pauline Meij, Anna Villa, Jacques J.M. Van Dongen, Jaap-Jan Zwaginga, Mirjam van der Burg, H. Bobby Gaspar, Arjan Lankester, Frank J.T. Staal, Karin Pike-Overzet
Published 2020-06-01