A conjoined universal helper epitope can unveil antitumor effects of a neoantigen vaccine targeting an MHC class I-restricted neoepitope

by Adam M. Swartz, Kendra L. Congdon, Smita K. Nair, Qi-Jing Li, James E. Herndon, Carter M. Suryadevara, Katherine A. Riccione, Gary E. Archer, Pamela K. Norberg, Luis A. Sanchez-Perez, John H. Sampson
Published 2021-01-01

CD27 stimulation unveils the efficacy of linked class I/II peptide vaccines in poorly immunogenic tumors by orchestrating a coordinated CD4/CD8 T cell response

by Katherine A. Riccione, Li-Zhen He, Peter E. Fecci, Pamela K. Norberg, Carter M. Suryadevara, Adam Swartz, Patrick Healy, Elizabeth Reap, Tibor Keler, Qi-Jing Li, Kendra L. Congdon, Luis Sanchez-Perez, John H. Sampson
Published 2018-12-01

A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma.

by John H Sampson, Robert J Schmittling, Gary E Archer, Kendra L Congdon, Smita K Nair, Elizabeth A Reap, Annick Desjardins, Allan H Friedman, Henry S Friedman, James E Herndon, April Coan, Roger E McLendon, David A Reardon, James J Vredenburgh, Darell D Bigner, Duane A Mitchell
Published 2012-01-01