Toxin-Based Targeted Therapy for Malignant Brain Tumors

by Vidyalakshmi Chandramohan, John H. Sampson, Ira Pastan, Darell D. Bigner
Published 2012-01-01

Monitoring Radiographic Brain Tumor Progression

by John H. Sampson, Darell D. Bigner, Allan H. Friedman, Charles W. Kanaly, Ankit I. Mehta
Published 2011-03-01

Pre-operative stereotactic radiosurgery treatment is preferred to post-operative treatment for smaller solitary brain metastases

by Hamidreza Aliabadi, Arian M. Nikpour, David S. Yoo, James E. Herndon, John H. Sampson, John P. Kirkpatrick
Published 2017-10-01

GLP toxicology study of a fully-human T cell redirecting CD3:EGFRvIII binding immunotherapeutic bispecific antibody.

by Patrick C Gedeon, Michael A Streicker, Teilo H Schaller, Gary E Archer, Micheal P Jokinen, John H Sampson
Published 2020-01-01

Imaging of Convection Enhanced Delivery of Toxins in Humans

by Allan H. Friedman, Darell D. Bigner, John H. Sampson, Ira Pastan, Martin Brady, Raghu Raghavan, Bryan D. Choi, Ankit I. Mehta
Published 2011-03-01

Targeting Immunometabolism in Glioblastoma

by Aditya A. Mohan, William H. Tomaszewski, Aden P. Haskell-Mendoza, Kelly M. Hotchkiss, Kirit Singh, Jessica L. Reedy, Peter E. Fecci, John H. Sampson, Mustafa Khasraw
Published 2021-06-01

A novel method for volumetric MRI response assessment of enhancing brain tumors.

by Charles W Kanaly, Dale Ding, Ankit I Mehta, Anthony F Waller, Ian Crocker, Annick Desjardins, David A Reardon, Allan H Friedman, Darell D Bigner, John H Sampson
Published 2011-01-01

A conjoined universal helper epitope can unveil antitumor effects of a neoantigen vaccine targeting an MHC class I-restricted neoepitope

by Adam M. Swartz, Kendra L. Congdon, Smita K. Nair, Qi-Jing Li, James E. Herndon, Carter M. Suryadevara, Katherine A. Riccione, Gary E. Archer, Pamela K. Norberg, Luis A. Sanchez-Perez, John H. Sampson
Published 2021-01-01

Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice.

by Luis A Sanchez-Perez, Bryan D Choi, Gary E Archer, Xiuyu Cui, Catherine Flores, Laura A Johnson, Robert J Schmittling, David Snyder, James E Herndon, Darell D Bigner, Duane A Mitchell, John H Sampson
Published 2013-01-01

CD27 stimulation unveils the efficacy of linked class I/II peptide vaccines in poorly immunogenic tumors by orchestrating a coordinated CD4/CD8 T cell response

by Katherine A. Riccione, Li-Zhen He, Peter E. Fecci, Pamela K. Norberg, Carter M. Suryadevara, Adam Swartz, Patrick Healy, Elizabeth Reap, Tibor Keler, Qi-Jing Li, Kendra L. Congdon, Luis Sanchez-Perez, John H. Sampson
Published 2018-12-01

EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma.

by Hongsheng Miao, Bryan D Choi, Carter M Suryadevara, Luis Sanchez-Perez, Shicheng Yang, Gabriel De Leon, Elias J Sayour, Roger McLendon, James E Herndon, Patrick Healy, Gary E Archer, Darell D Bigner, Laura A Johnson, John H Sampson
Published 2014-01-01

A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma.

by John H Sampson, Robert J Schmittling, Gary E Archer, Kendra L Congdon, Smita K Nair, Elizabeth A Reap, Annick Desjardins, Allan H Friedman, Henry S Friedman, James E Herndon, April Coan, Roger E McLendon, David A Reardon, James J Vredenburgh, Darell D Bigner, Duane A Mitchell
Published 2012-01-01

Temozolomide lymphodepletion enhances CAR abundance and correlates with antitumor efficacy against established glioblastoma

by Carter M. Suryadevara, Rupen Desai, Melissa L. Abel, Katherine A. Riccione, Kristen A. Batich, Steven H. Shen, Pakawat Chongsathidkiet, Patrick C. Gedeon, Aladine A. Elsamadicy, David J. Snyder, James E. Herndon, Patrick Healy, Gary E. Archer, Bryan D. Choi, Peter E. Fecci, John H. Sampson, Luis Sanchez-Perez
Published 2018-06-01

Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy

by Matthias Gromeier, Michael C. Brown, Gao Zhang, Xiang Lin, Yeqing Chen, Zhi Wei, Nike Beaubier, Hai Yan, Yiping He, Annick Desjardins, James E. Herndon, Frederick S. Varn, Roel G. Verhaak, Junfei Zhao, Dani P. Bolognesi, Allan H. Friedman, Henry S. Friedman, Frances McSherry, Andrea M. Muscat, Eric S. Lipp, Smita K. Nair, Mustafa Khasraw, Katherine B. Peters, Dina Randazzo, John H. Sampson, Roger E. McLendon, Darell D. Bigner, David M. Ashley
Published 2021-01-01

Outcomes in Patients With 4 to 10 Brain Metastases Treated With Dose-Adapted Single-Isocenter Multitarget Stereotactic Radiosurgery: A Prospective Study

by Grace J. Kim, MD, PhD, Evan D. Buckley, MS, James E. Herndon, PhD, Karen J. Allen, NP, Tyketra S. Dale, NP, Justus D. Adamson, PhD, Lam Lay, BA, William M. Giles, PhD, Anna E. Rodrigues, PhD, Zhiheng Wang, PhD, Chris R. Kelsey, MD, Jordan A. Torok, Jr, MD, Junzo P. Chino, MD, Peter E. Fecci, MD, PhD, John H. Sampson, MD, PhD, MBA, Carey K. Anders, MD, Scott R. Floyd, MD, PhD, Fang-Fang Yin, PhD, John P. Kirkpatrick, MD, PhD
Published 2021-11-01