Biomolecular Condensates and Cancer

by Boija, Ann, Klein, Isaac A., Young, Richard A.
Published 2021

Parallel Automated Flow Synthesis of Covalent Protein Complexes That Can Inhibit MYC-Driven Transcription

by Pomplun, Sebastian, Jbara, Muhammad, Schissel, Carly K, Wilson Hawken, Susana, Boija, Ann, Li, Charles, Klein, Isaac, Pentelute, Bradley L
Published 2022

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

by Klein, Isaac A., Sabari, Benjamin R., Dall'Agnese, Alessandra, Coffey, Eliot L., Zamudio, Alicia V., Manteiga, John C., Hannett, Nancy M., Abraham, Brian J., Afeyan, Lena K., Guo, Yang E., Schuijers, Jurian, Lee, Tong Ihn, Taatjes, Dylan J., Young, Richard A., Shrinivas, Krishna,Ph. D.Massachusetts Institute of Technology, Li, Charles H.
Published 2020

Coactivator condensation at super-enhancers links phase separation and gene control

by Sabari, Benjamin R., Dall'Agnese, Alessandra, Boija, Ann, Klein, Isaac A., Abraham, Brian J., Hannett, Nancy M., Guo, Yang E., Day, Daniel S., Schuijers, Jurian, Hnisz, Denes, Lee, Tong Ihn, Coffey, Eliot Leo, Shrinivas, Krishna, Zamudio Montes de Oca, Alicia, Manteiga, John Colonnese, Li, Charles Han, Vasile, Eliza, Cisse, Ibrahim I, Chakraborty, Arup K, Sharp, Phillip A., Young, Richard A.
Published 2019

Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes

by Zamudio Montes de Oca, Alicia, Dall'Agnese, Alessandra, Henninger, Jonathan E., Manteiga, John Colonnese, Afeyan, Lena K., Hannett, Nancy M., Coffey, Eliot Leo, Li, Charles Han, Oksuz, Ozgur, Sabari, Benjamin R., Boija, Ann, Klein, Isaac A., Hawken, Susana W, Spille, Jan Hendrik, Cisse, Ibrahim I, Abraham, Brian Joseph, Lee, Tong Ihn, Taatjes, Dylan J., Schuijers, Jurian, Young, Richard A.
Published 2021