Arsenic trioxide overcomes rapamycin-induced feedback activation of AKT and ERK signaling to enhance the anti-tumor effects in breast cancer.

by Cynthia Guilbert, Matthew G Annis, Zhifeng Dong, Peter M Siegel, Wilson H Miller, Koren K Mann
Published 2013-01-01

Metabolomic Profiling Reveals Cellular Reprogramming of B-Cell Lymphoma by a Lysine Deacetylase Inhibitor through the Choline Pathway

by Benet Pera, Jan Krumsiek, Sarit E. Assouline, Rossella Marullo, Jayeshkumar Patel, Jude M. Phillip, Lidia Román, Koren K. Mann, Leandro Cerchietti
Published 2018-02-01

Arsenic Exposure Increases Monocyte Adhesion to the Vascular Endothelium, a Pro-Atherogenic Mechanism.

by Maryse Lemaire, Luis Fernando Negro Silva, Catherine A Lemarié, Alicia M Bolt, Manuel Flores Molina, Regina M Krohn, Judit E Smits, Stéphanie Lehoux, Koren K Mann
Published 2015-01-01

The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression

by Ryuhjin Ahn, Valérie Sabourin, Alicia M. Bolt, Steven Hébert, Stephanie Totten, Nicolas De Jay, Maria Carolina Festa, Yoon Kow Young, Young Kyuen Im, Tony Pawson, Antonis E. Koromilas, William J. Muller, Koren K. Mann, Claudia L. Kleinman, Josie Ursini-Siegel
Published 2017-03-01

The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer

by Nour Ghaddar, Shuo Wang, Bethany Woodvine, Jothilatha Krishnamoorthy, Vincent van Hoef, Cedric Darini, Urszula Kazimierczak, Nicolas Ah-son, Helmuth Popper, Myriam Johnson, Leah Officer, Ana Teodósio, Massimo Broggini, Koren K. Mann, Maria Hatzoglou, Ivan Topisirovic, Ola Larsson, John Le Quesne, Antonis E. Koromilas
Published 2021-07-01

Monitoring response and resistance to the novel arsenical darinaparsin in an AML patient

by Torsten Holm eNielsen, Nathalie eJohnson, Nicolas eGarnier, Stanley eKwan, Lu eYao, Eftihia eCocolakis, Josée eHébert, Robert A. Morgan, Éric ePaquet, Kevin P. Callahan, Craig T. Jordan, Sarit eAssouline, Wilson H. Miller, Koren K. Mann
Published 2013-02-01

Apoptotic Blocks in Primary Non-Hodgkin B Cell Lymphomas Identified by BH3 Profiling

by Ryan N. Rys, Claudia M. Wever, Dominique Geoffrion, Christophe Goncalves, Artin Ghassemian, Eugene Brailovski, Jeremy Ryan, Liliana Stoica, Josée Hébert, Tina Petrogiannis-Haliotis, Svetlana Dmitrienko, Saul Frenkiel, Annette Staiger, German Ott, Christian Steidl, David W. Scott, Pierre Sesques, Sonia del Rincon, Koren K. Mann, Anthony Letai, Nathalie A. Johnson
Published 2021-02-01