The genetics of axonal transport and axonal transport disorders.

by Jason E Duncan, Lawrence S B Goldstein
Published 2006-09-01

The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila.

by Jason E Duncan, Nikki K Lytle, Alfredo Zuniga, Lawrence S B Goldstein
Published 2013-01-01

Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism.

by Rhiannon L Killian, Jessica D Flippin, Cheryl M Herrera, Angels Almenar-Queralt, Lawrence S B Goldstein
Published 2012-01-01

Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer’s Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein

by Jessica E. Young, Lauren K. Fong, Harald Frankowski, Gregory A. Petsko, Scott A. Small, Lawrence S.B. Goldstein
Published 2018-03-01

Examination of potential mechanisms of amyloid-induced defects in neuronal transport

by Sameer B. Shah, Rhiannon Nolan, Emily Davis, Gorazd B. Stokin, Ingrid Niesman, Isabel Canto, Charles Glabe, Lawrence S.B. Goldstein
Published 2009-10-01

Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer’s Disease Mutations

by Grace Woodruff, Sol M. Reyna, Mariah Dunlap, Rik Van Der Kant, Julia A. Callender, Jessica E. Young, Elizabeth A. Roberts, Lawrence S.B. Goldstein
Published 2016-10-01

The Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells

by Grace Woodruff, Jessica E. Young, Fernando J. Martinez, Floyd Buen, Athurva Gore, Jennifer Kinaga, Zhe Li, Shauna H. Yuan, Kun Zhang, Lawrence S.B. Goldstein
Published 2013-11-01

A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP.

by April M Weissmiller, Orlangie Natera-Naranjo, Sol M Reyna, Matthew L Pearn, Xiaobei Zhao, Phuong Nguyen, Soan Cheng, Lawrence S B Goldstein, Rudolph E Tanzi, Steven L Wagner, William C Mobley, Chengbiao Wu
Published 2015-01-01

High-Throughput and Cost-Effective Characterization of Induced Pluripotent Stem Cells

by Matteo D'Antonio, Grace Woodruff, Jason L. Nathanson, Agnieszka D'Antonio-Chronowska, Angelo Arias, Hiroko Matsui, Roy Williams, Cheryl Herrera, Sol M. Reyna, Gene W. Yeo, Lawrence S.B. Goldstein, Athanasia D. Panopoulos, Kelly A. Frazer
Published 2017-04-01

Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells.

by Shauna H Yuan, Jody Martin, Jeanne Elia, Jessica Flippin, Rosanto I Paramban, Mike P Hefferan, Jason G Vidal, Yangling Mu, Rhiannon L Killian, Mason A Israel, Nil Emre, Silvia Marsala, Martin Marsala, Fred H Gage, Lawrence S B Goldstein, Christian T Carson
Published 2011-03-01

Evidence generation and reproducibility in cell and gene therapy research: A call to action

by Mohamed Abou-el-Enein, Aris Angelis, Frederick R. Appelbaum, Nancy C. Andrews, Susan E. Bates, Arlene S. Bierman, Malcolm K. Brenner, Marina Cavazzana, Michael A. Caligiuri, Hans Clevers, Emer Cooke, George Q. Daley, Victor J. Dzau, Lee M. Ellis, Harvey V. Fineberg, Lawrence S.B. Goldstein, Stephen Gottschalk, Margaret A. Hamburg, Donald E. Ingber, Donald B. Kohn, Adrian R. Krainer, Marcela V. Maus, Peter Marks, Christine L. Mummery, Roderic I. Pettigrew, Joni L. Rutter, Sarah A. Teichmann, Andre Terzic, Fyodor D. Urnov, David A. Williams, Jedd D. Wolchok, Mark Lawler, Cameron J. Turtle, Gerhard Bauer, John P.A. Ioannidis
Published 2021-09-01

iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types

by Athanasia D. Panopoulos, Matteo D'Antonio, Paola Benaglio, Roy Williams, Sherin I. Hashem, Bernhard M. Schuldt, Christopher DeBoever, Angelo D. Arias, Melvin Garcia, Bradley C. Nelson, Olivier Harismendy, David A. Jakubosky, Margaret K.R. Donovan, William W. Greenwald, KathyJean Farnam, Megan Cook, Victor Borja, Carl A. Miller, Jonathan D. Grinstein, Frauke Drees, Jonathan Okubo, Kenneth E. Diffenderfer, Yuriko Hishida, Veronica Modesto, Carl T. Dargitz, Rachel Feiring, Chang Zhao, Aitor Aguirre, Thomas J. McGarry, Hiroko Matsui, He Li, Joaquin Reyna, Fangwen Rao, Daniel T. O'Connor, Gene W. Yeo, Sylvia M. Evans, Neil C. Chi, Kristen Jepsen, Naoki Nariai, Franz-Josef Müller, Lawrence S.B. Goldstein, Juan Carlos Izpisua Belmonte, Eric Adler, Jeanne F. Loring, W. Travis Berggren, Agnieszka D'Antonio-Chronowska, Erin N. Smith, Kelly A. Frazer
Published 2017-04-01