Synchrotron scanning reveals the palaeoneurology of the head-butting Moschops capensis (Therapsida, Dinocephalia)

by Julien Benoit, Paul R. Manger, Luke Norton, Vincent Fernandez, Bruce S. Rubidge
Published 2017-08-01

Increased lipid availability for three days reduces whole body glucose uptake, impairs muscle mitochondrial function and initiates opposing effects on PGC-1α promoter methylation i...

by Roy Eldor, Luke Norton, Marcel Fourcaudot, Cynthia Galindo, Ralph A DeFronzo, Muhammad Abdul-Ghani
Published 2017-01-01

Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease

by Chris E. Shannon, Mukundan Ragavan, Juan Pablo Palavicini, Marcel Fourcaudot, Terry M Bakewell, Ivan A. Valdez, Iriscilla Ayala, Eunsook S. Jin, Muniswamy Madesh, Xianlin Han, Matthew E. Merritt, Luke Norton
Published 2021-03-01

Proximal tubular epithelial insulin receptor mediates high-fat diet–induced kidney injury

by Hak Joo Lee, Meenalakshmi M. Mariappan, Luke Norton, Terry Bakewell, Denis Feliers, Sae Byeol Oh, Andrew Donati, Cherubina S. Rubannelsonkumar, Manjeri A. Venkatachalam, Stephen E. Harris, Isabelle Rubera, Michel Tauc, Goutam Ghosh Choudhury, C. Ronald Kahn, Kumar Sharma, Ralph A. DeFronzo, Balakuntalam S. Kasinath
Published 2021-02-01

The tumor suppressor TMEM127 regulates insulin sensitivity in a tissue-specific manner

by Subramanya Srikantan, Yilun Deng, Zi-Ming Cheng, Anqi Luo, Yuejuan Qin, Qing Gao, Glaiza-Mae Sande-Docor, Sifan Tao, Xingyu Zhang, Nathan Harper, Chris E. Shannon, Marcel Fourcaudot, Zhi Li, Balakuntalam S. Kasinath, Stephen Harrison, Sunil Ahuja, Robert L. Reddick, Lily Q. Dong, Muhammad Abdul-Ghani, Luke Norton, Ricardo C. T. Aguiar, Patricia L. M. Dahia
Published 2019-10-01

Transcriptomic identification of ADH1B as a novel candidate gene for obesity and insulin resistance in human adipose tissue in Mexican Americans from the Veterans Administration Ge...

by Deidre A Winnier, Marcel Fourcaudot, Luke Norton, Muhammad A Abdul-Ghani, Shirley L Hu, Vidya S Farook, Dawn K Coletta, Satish Kumar, Sobha Puppala, Geetha Chittoor, Thomas D Dyer, Rector Arya, Melanie Carless, Donna M Lehman, Joanne E Curran, Douglas T Cromack, Devjit Tripathy, John Blangero, Ravindranath Duggirala, Harald H H Göring, Ralph A DeFronzo, Christopher P Jenkinson
Published 2015-01-01

Further evidence supporting a potential role for ADH1B in obesity

by Liza D. Morales, Douglas T. Cromack, Devjit Tripathy, Marcel Fourcaudot, Satish Kumar, Joanne E. Curran, Melanie Carless, Harald H. H. Göring, Shirley L. Hu, Juan Carlos Lopez-Alvarenga, Kristina M. Garske, Päivi Pajukanta, Kerrin S. Small, Craig A. Glastonbury, Swapan K. Das, Carl Langefeld, Robert L. Hanson, Wen-Chi Hsueh, Luke Norton, Rector Arya, Srinivas Mummidi, John Blangero, Ralph A. DeFronzo, Ravindranath Duggirala, Christopher P. Jenkinson
Published 2021-01-01

Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation

by Dhanendra Tomar, Fabián Jaña, Zhiwei Dong, William J. Quinn, III, Pooja Jadiya, Sarah L. Breves, Cassidy C. Daw, Subramanya Srikantan, Santhanam Shanmughapriya, Neeharika Nemani, Edmund Carvalho, Aparna Tripathi, Alison M. Worth, Xueqian Zhang, Roshanak Razmpour, Ajay Seelam, Stephen Rhode, Anuj V. Mehta, Michael Murray, Daniel Slade, Servio H. Ramirez, Prashant Mishra, Glenn S. Gerhard, Jeffrey Caplan, Luke Norton, Kumar Sharma, Sudarsan Rajan, Darius Balciunas, Dayanjan S. Wijesinghe, Rexford S. Ahima, Joseph A. Baur, Muniswamy Madesh
Published 2019-03-01