TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion.

by Nirmalya Dey, Nandini Ghosh-Choudhury, Balakuntalam S Kasinath, Goutam Ghosh Choudhury
Published 2012-01-01

Fatigue characteristics on dialysis and non-dialysis days in patients with chronic kidney failure on maintenance hemodialysis

by Subrata Debnath, Rain Rueda, Shweta Bansal, Balakuntalam S. Kasinath, Kumar Sharma, Carlos Lorenzo
Published 2021-03-01

HIV-1 promotes renal tubular epithelial cell protein synthesis: role of mTOR pathway.

by Shabina Rehman, Mohammad Husain, Anju Yadav, Balakuntalam S Kasinath, Ashwani Malhotra, Pravin C Singhal
Published 2012-01-01

TGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen I (α2) gene expression.

by Falguni Das, Amit Bera, Nandini Ghosh-Choudhury, Hanna E Abboud, Balakuntalam S Kasinath, Goutam Ghosh Choudhury
Published 2014-01-01

Akt2 causes TGFβ-induced deptor downregulation facilitating mTOR to drive podocyte hypertrophy and matrix protein expression.

by Falguni Das, Nandini Ghosh-Choudhury, Doug Yoon Lee, Yves Gorin, Balakuntalam S Kasinath, Goutam Ghosh Choudhury
Published 2018-01-01

microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion.

by Nirmalya Dey, Falguni Das, Nandini Ghosh-Choudhury, Chandi Charan Mandal, Dipen J Parekh, Karen Block, Balakuntalam S Kasinath, Hanna E Abboud, Goutam Ghosh Choudhury
Published 2012-01-01

Proximal tubular epithelial insulin receptor mediates high-fat diet–induced kidney injury

by Hak Joo Lee, Meenalakshmi M. Mariappan, Luke Norton, Terry Bakewell, Denis Feliers, Sae Byeol Oh, Andrew Donati, Cherubina S. Rubannelsonkumar, Manjeri A. Venkatachalam, Stephen E. Harris, Isabelle Rubera, Michel Tauc, Goutam Ghosh Choudhury, C. Ronald Kahn, Kumar Sharma, Ralph A. DeFronzo, Balakuntalam S. Kasinath
Published 2021-02-01

The tumor suppressor TMEM127 regulates insulin sensitivity in a tissue-specific manner

by Subramanya Srikantan, Yilun Deng, Zi-Ming Cheng, Anqi Luo, Yuejuan Qin, Qing Gao, Glaiza-Mae Sande-Docor, Sifan Tao, Xingyu Zhang, Nathan Harper, Chris E. Shannon, Marcel Fourcaudot, Zhi Li, Balakuntalam S. Kasinath, Stephen Harrison, Sunil Ahuja, Robert L. Reddick, Lily Q. Dong, Muhammad Abdul-Ghani, Luke Norton, Ricardo C. T. Aguiar, Patricia L. M. Dahia
Published 2019-10-01