Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells

by Miriam Cnop, Sanna Toivonen, Mariana Igoillo-Esteve, Paraskevi Salpea
Published 2017-09-01

tRNA Biology in the Pathogenesis of Diabetes: Role of Genetic and Environmental Factors

by Maria Nicol Arroyo, Jonathan Alex Green, Miriam Cnop, Mariana Igoillo-Esteve
Published 2021-01-01

The pentose phosphate pathway in Trypanosoma cruzi: a potential target for the chemotherapy of Chagas disease

by Mariana Igoillo-Esteve, Dante Maugeri, Ana L. Stern, Paula Beluardi, Juan J. Cazzulo
Published 2007-12-01

Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis.

by Katleen Lemaire, Rodrigo F Moura, Mikaela Granvik, Mariana Igoillo-Esteve, Hans E Hohmeier, Nico Hendrickx, Christopher B Newgard, Etienne Waelkens, Miriam Cnop, Frans Schuit
Published 2011-04-01

Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target.

by Andrés Alloatti, Shreedhara Gupta, Melisa Gualdrón-López, Mariana Igoillo-Esteve, Paul A Nguewa, Gladys Deumer, Pierre Wallemacq, Silvia G Altabe, Paul A M Michels, Antonio D Uttaro
Published 2010-12-01

Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity

by Maria Lytrivi, Kassem Ghaddar, Miguel Lopes, Victoria Rosengren, Anthony Piron, Xiaoyan Yi, Henrik Johansson, Janne Lehtiö, Mariana Igoillo-Esteve, Daniel A. Cunha, Lorella Marselli, Piero Marchetti, Henrik Ortsäter, Decio L. Eizirik, Miriam Cnop
Published 2020-08-01

tRNA methyltransferase homolog gene TRMT10A mutation in young onset diabetes and primary microcephaly in humans.

by Mariana Igoillo-Esteve, Anne Genin, Nelle Lambert, Julie Désir, Isabelle Pirson, Baroj Abdulkarim, Nicolas Simonis, Anais Drielsma, Lorella Marselli, Piero Marchetti, Pierre Vanderhaeghen, Décio L Eizirik, Wim Wuyts, Cécile Julier, Ali J Chakera, Sian Ellard, Andrew T Hattersley, Marc Abramowicz, Miriam Cnop
Published 2013-10-01

The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.

by Décio L Eizirik, Michael Sammeth, Thomas Bouckenooghe, Guy Bottu, Giorgia Sisino, Mariana Igoillo-Esteve, Fernanda Ortis, Izortze Santin, Maikel L Colli, Jenny Barthson, Luc Bouwens, Linda Hughes, Lorna Gregory, Gerton Lunter, Lorella Marselli, Piero Marchetti, Mark I McCarthy, Miriam Cnop
Published 2012-01-01

Insulinoma Localization by Glucagon-Like Peptide-1 Receptor Imaging After 18 Years of Hypoglycemia

by Aglaia Kyrilli, MD, Mariana Igoillo-Esteve, PhD, Françoise Féry, MD, PhD, Fabio A. Grieco, PhD, Pierre Eisendrath, MD, Didier Blocklet, MD, Serge Goldman, MD, PhD, Jean-Claude Henquin, MD, PhD, Martin Gotthardt, MD, PhD, Miriam Cnop, MD, PhD
Published 2015-01-01