Potentiated Hsp104 variants suppress toxicity of diverse neurodegenerative disease-linked proteins

by Meredith E. Jackrel, James Shorter
Published 2014-10-01

Prion-Like Proteins in Phase Separation and Their Link to Disease

by Macy L. Sprunger, Meredith E. Jackrel
Published 2021-07-01

Functional analysis of proposed substrate-binding residues of Hsp104.

by Matthew K Howard, Brian S Sohn, Julius von Borcke, Andy Xu, Meredith E Jackrel
Published 2020-01-01

Therapeutic genetic variation revealed in diverse Hsp104 homologs

by Zachary M March, Katelyn Sweeney, Hanna Kim, Xiaohui Yan, Laura M Castellano, Meredith E Jackrel, JiaBei Lin, Edward Chuang, Edward Gomes, Corey W Willicott, Karolina Michalska, Robert P Jedrzejczak, Andrzej Joachimiak, Kim A Caldwell, Guy A Caldwell, Ophir Shalem, James Shorter
Published 2020-12-01

Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity

by Amber Tariq, JiaBei Lin, Meredith E. Jackrel, Christina D. Hesketh, Peter J. Carman, Korrie L. Mack, Rachel Weitzman, Craig Gambogi, Oscar A. Hernandez Murillo, Elizabeth A. Sweeny, Esin Gurpinar, Adam L. Yokom, Stephanie N. Gates, Keolamau Yee, Saurabh Sudesh, Jacob Stillman, Alexandra N. Rizo, Daniel R. Southworth, James Shorter
Published 2019-08-01