Off-Target and Tumor-Specific Accumulation of Monocytes, Macrophages and Myeloid-Derived Suppressor Cells after Systemic Injection

by Francis Combes, Séan Mc Cafferty, Evelyne Meyer, Niek N. Sanders
Published 2018-08-01

T cell epitope mapping of the e-protein of West Nile virus in BALB/c mice.

by Marina De Filette, Stefan Chabierski, Oliwia Andries, Sebastian Ulbert, Niek N Sanders
Published 2014-01-01

Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer

by Jonas Steenbrugge, Jonas Steenbrugge, Jonas Steenbrugge, Niels Vander Elst, Kristel Demeyere, Olivier De Wever, Olivier De Wever, Niek N. Sanders, Niek N. Sanders, Wim Van Den Broeck, Luc Dirix, Steven Van Laere, Evelyne Meyer, Evelyne Meyer
Published 2019-12-01

Improving the Repeatability and Efficacy of Intradermal Electroporated Self-Replicating mRNA

by Hanne Huysmans, Joyca De Temmerman, Zifu Zhong, Séan Mc Cafferty, Francis Combes, Freddy Haesebrouck, Niek N. Sanders
Published 2019-09-01

The Opposing Effect of Type I IFN on the T Cell Response by Non-modified mRNA-Lipoplex Vaccines Is Determined by the Route of Administration

by Lien Van Hoecke, Kenny Roose, Marlies Ballegeer, Zifu Zhong, Niek N. Sanders, Stefaan De Koker, Xavier Saelens, Sandra Van Lint
Published 2020-12-01

Mononuclear but Not Polymorphonuclear Phagocyte Depletion Increases Circulation Times and Improves Mammary Tumor-Homing Efficiency of Donor Bone Marrow-Derived Monocytes

by Francis Combes, Alexandros Marios Sofias, Séan Mc Cafferty, Hanne Huysmans, Joyca De Temmerman, Sjoerd Hak, Evelyne Meyer, Niek N. Sanders
Published 2019-11-01

Expression Kinetics and Innate Immune Response after Electroporation and LNP-Mediated Delivery of a Self-Amplifying mRNA in the Skin

by Hanne Huysmans, Zifu Zhong, Joyca De Temmerman, Barbara L. Mui, Ying K. Tam, Séan Mc Cafferty, Arlieke Gitsels, Daisy Vanrompay, Niek N. Sanders
Published 2019-09-01

OMO-1 reduces progression and enhances cisplatin efficacy in a 4T1-based non-c-MET addicted intraductal mouse model for triple-negative breast cancer

by Jonas Steenbrugge, Niels Vander Elst, Kristel Demeyere, Olivier De Wever, Niek N. Sanders, Wim Van Den Broeck, Eric Ciamporcero, Timothy Perera, Evelyne Meyer
Published 2021-03-01

Non-classical proIL-1beta activation during mammary gland infection is pathogen-dependent but caspase-1 independent.

by Koen Breyne, Steven K Cool, Dieter Demon, Kristel Demeyere, Tom Vandenberghe, Peter Vandenabeele, Harald Carlsen, Wim Van Den Broeck, Niek N Sanders, Evelyne Meyer
Published 2014-01-01

Vaccination of mice using the West Nile virus E-protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects mice against a lethal challenge.

by Marina De Filette, Silke Soehle, Sebastian Ulbert, Justin Richner, Michael S Diamond, Alessandro Sinigaglia, Luisa Barzon, Stefan Roels, Julianna Lisziewicz, Orsolya Lorincz, Niek N Sanders
Published 2014-01-01

Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer

by Jonas Steenbrugge, Koen Breyne, Kristel Demeyere, Olivier De Wever, Niek N. Sanders, Wim Van Den Broeck, Cecile Colpaert, Peter Vermeulen, Steven Van Laere, Evelyne Meyer
Published 2018-08-01

Immunogenicity and Protection Efficacy of a Naked Self-Replicating mRNA-Based Zika Virus Vaccine

by Zifu Zhong, João Paulo Portela Catani, Séan Mc Cafferty, Liesbeth Couck, Wim Van Den Broeck, Nina Gorlé, Roosmarijn E. Vandenbroucke, Bert Devriendt, Sebastian Ulbert, Lieselotte Cnops, Johan Michels, Kevin K. Ariën, Niek N. Sanders
Published 2019-08-01