Allosteric inhibitors of the NS3 protease from the hepatitis C virus.

by Olga Abian, Sonia Vega, Javier Sancho, Adrian Velazquez-Campoy
Published 2013-01-01

NS3 Protease from Hepatitis C Virus: Biophysical Studies on an Intrinsically Disordered Protein Domain

by Adrian Velazquez-Campoy, Olga Abian, Carlos Marcuello, Anabel Lostao, Sonia Vega, Jose L. Neira
Published 2013-06-01

In Vitro Antiviral Activity of Tyrosinase from Mushroom <i>Agaricus bisporus</i> against Hepatitis C Virus

by David Lopez-Tejedor, Rafael Claveria-Gimeno, Adrian Velazquez-Campoy, Olga Abian, Jose M. Palomo
Published 2021-08-01

The Paralogue of the Intrinsically Disordered Nuclear Protein 1 Has a Nuclear Localization Sequence that Binds to Human Importin α3

by José L. Neira, Bruno Rizzuti, Ana Jiménez-Alesanco, Olga Abián, Adrián Velázquez-Campoy, Juan L. Iovanna
Published 2020-10-01

Molecular Context-Dependent Effects Induced by Rett Syndrome-Associated Mutations in MeCP2

by David Ortega-Alarcon, Rafael Claveria-Gimeno, Sonia Vega, Olga C. Jorge-Torres, Manel Esteller, Olga Abian, Adrian Velazquez-Campoy
Published 2020-11-01

A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin

by José L. Neira, Bruno Rizzuti, Ana Jiménez-Alesanco, Martina Palomino-Schätzlein, Olga Abián, Adrián Velázquez-Campoy, Juan L. Iovanna
Published 2020-09-01

Thermal Liquid Biopsy (TLB): A Predictive Score Derived from Serum Thermograms as a Clinical Tool for Screening Lung Cancer Patients

by Alberto Rodrigo, Jorge L. Ojeda, Sonia Vega, Oscar Sanchez-Gracia, Angel Lanas, Dolores Isla, Adrian Velazquez-Campoy, Olga Abian
Published 2019-07-01

Stabilization Effect of Intrinsically Disordered Regions on Multidomain Proteins: The Case of the Methyl-CpG Protein 2, MeCP2

by David Ortega-Alarcon, Rafael Claveria-Gimeno, Sonia Vega, Olga C. Jorge-Torres, Manel Esteller, Olga Abian, Adrian Velazquez-Campoy
Published 2021-08-01

Biosourced All-Acrylic ABA Block Copolymers with Lactic Acid-Based Soft Phase

by Nabil Bensabeh, Ana Jiménez-Alesanco, Ilme Liblikas, Juan C. Ronda, Virginia Cádiz, Marina Galià, Lauri Vares, Olga Abián, Gerard Lligadas
Published 2020-12-01

Sub-Micromolar Inhibition of SARS-CoV-2 3CLpro by Natural Compounds

by Bruno Rizzuti, Laura Ceballos-Laita, David Ortega-Alarcon, Ana Jimenez-Alesanco, Sonia Vega, Fedora Grande, Filomena Conforti, Olga Abian, Adrian Velazquez-Campoy
Published 2021-09-01

Janus Dendrimers to Assess the Anti-HCV Activity of Molecules in Cell-Assays

by María San Anselmo, Alexandre Lancelot, Julia E. Egido, Rafael Clavería-Gimeno, Álvaro Casanova, José Luis Serrano, Silvia Hernández-Ainsa, Olga Abian, Teresa Sierra
Published 2020-11-01

Rutin Is a Low Micromolar Inhibitor of SARS-CoV-2 Main Protease 3CLpro: Implications for Drug Design of Quercetin Analogs

by Bruno Rizzuti, Fedora Grande, Filomena Conforti, Ana Jimenez-Alesanco, Laura Ceballos-Laita, David Ortega-Alarcon, Sonia Vega, Hugh T. Reyburn, Olga Abian, Adrian Velazquez-Campoy
Published 2021-04-01

Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma

by Patricia Santofimia-Castaño, Yi Xia, Ling Peng, Adrián Velázquez-Campoy, Olga Abián, Wenjun Lan, Gwen Lomberk, Raul Urrutia, Bruno Rizzuti, Philippe Soubeyran, José Luis Neira, Juan Iovanna
Published 2019-11-01

Fluorescence Liquid Biopsy for Cancer Detection Is Improved by Using Cationic Dendronized Hyperbranched Polymer

by Violeta Morcuende-Ventura, Sonia Hermoso-Durán, Natalia Abian-Franco, Roberto Pazo-Cid, Jorge L. Ojeda, Sonia Vega, Oscar Sanchez-Gracia, Adrian Velazquez-Campoy, Teresa Sierra, Olga Abian
Published 2021-06-01

Thermal Liquid Biopsy (TLB) Focused on Benign and Premalignant Pancreatic Cyst Diagnosis

by Sonia Hermoso-Durán, Guillermo García-Rayado, Laura Ceballos-Laita, Carlos Sostres, Sonia Vega, Judith Millastre, Oscar Sánchez-Gracia, Jorge L. Ojeda, Ángel Lanas, Adrián Velázquez-Campoy, Olga Abian
Published 2021-12-01

Rationally designed interfacial peptides are efficient in vitro inhibitors of HIV-1 capsid assembly with antiviral activity.

by Rebeca Bocanegra, María Nevot, Rosa Doménech, Inmaculada López, Olga Abián, Alicia Rodríguez-Huete, Claudio N Cavasotto, Adrián Velázquez-Campoy, Javier Gómez, Miguel Ángel Martínez, José Luis Neira, Mauricio G Mateu
Published 2011-01-01

Thermal Liquid Biopsy (TLB) of Blood Plasma as a Potential Tool to Help in the Early Diagnosis of Multiple Sclerosis

by Ferdinanda Annesi, Sonia Hermoso-Durán, Bruno Rizzuti, Rosalinda Bruno, Domenico Pirritano, Alfredo Petrone, Francesco Del Giudice, Jorge Ojeda, Sonia Vega, Oscar Sanchez-Gracia, Adrian Velazquez-Campoy, Olga Abian, Rita Guzzi
Published 2021-04-01

ZZW-115–dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents

by Wenjun Lan, Patricia Santofimia-Castaño, Mirna Swayden, Yi Xia, Zhengwei Zhou, Stephane Audebert, Luc Camoin, Can Huang, Ling Peng, Ana Jiménez-Alesanco, Adrián Velázquez-Campoy, Olga Abián, Gwen Lomberk, Raul Urrutia, Bruno Rizzuti, Vincent Geli, Philippe Soubeyran, José L. Neira, Juan Iovanna
Published 2020-09-01

Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of M^pro and Its Antiviral Activity in Cells against SARS-CoV-2

by Francesca Mangiavacchi, Pawel Botwina, Elena Menichetti, Luana Bagnoli, Ornelio Rosati, Francesca Marini, Sérgio F. Fonseca, Laura Abenante, Diego Alves, Agnieszka Dabrowska, Anna Kula-Pacurar, David Ortega-Alarcon, Ana Jimenez-Alesanco, Laura Ceballos-Laita, Sonia Vega, Bruno Rizzuti, Olga Abian, Eder J. Lenardão, Adrian Velazquez-Campoy, Krzysztof Pyrc, Luca Sancineto, Claudio Santi
Published 2021-06-01

MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

by Alexia Martínez de Paz, Leila Khajavi, Hélène Martin, Rafael Claveria-Gimeno, Susanne Tom Dieck, Manjinder S. Cheema, Jose V. Sanchez-Mut, Malgorzata M. Moksa, Annaick Carles, Nick I. Brodie, Taimoor I. Sheikh, Melissa E. Freeman, Evgeniy V. Petrotchenko, Christoph H. Borchers, Erin M. Schuman, Matthias Zytnicki, Adrian Velazquez-Campoy, Olga Abian, Martin Hirst, Manel Esteller, John B. Vincent, Cécile E. Malnou, Juan Ausió
Published 2019-10-01