Experimental Mutations in Superoxide Dismutase 1 Provide Insight into Potential Mechanisms Involved in Aberrant Aggregation in Familial Amyotrophic Lateral Sclerosis

by Anthony M. Crown, Brittany L. Roberts, Keith Crosby, Hilda Brown, Jacob I. Ayers, P. John Hart, David R. Borchelt
Published 2019-03-01

Mycoplasma pneumoniae Community-Acquired Respiratory Distress Syndrome Toxin Uses a Novel KELED Sequence for Retrograde Transport and Subsequent Cytotoxicity

by Kumaraguruparan Ramasamy, Sowmya Balasubramanian, Krishnan Manickam, Lavanya Pandranki, Alexander B. Taylor, P. John Hart, Joel B. Baseman, T. R. Kannan, R. John Collier
Published 2018-01-01

RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin

by Zinaida Yudina, Amanda Roa, Rory Johnson, Nikolaos Biris, Daniel A. de Souza Aranha Vieira, Vladislav Tsiperson, Natalia Reszka, Alexander B. Taylor, P. John Hart, Borries Demeler, Felipe Diaz-Griffero, Dmitri N. Ivanov
Published 2015-08-01

Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?

by Anastasia R. Rugel, Meghan A. Guzman, Alexander B. Taylor, Frédéric D. Chevalier, Reid S. Tarpley, Stanton F. McHardy, Xiaohang Cao, Stephen P. Holloway, Timothy J.C. Anderson, P. John Hart, Philip T. LoVerde
Published 2020-08-01

Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine.

by Alexander B Taylor, Livia Pica-Mattoccia, Chiara M Polcaro, Enrica Donati, Xiaohang Cao, Annalisa Basso, Alessandra Guidi, Anastasia R Rugel, Stephen P Holloway, Timothy J C Anderson, P John Hart, Donato Cioli, Philip T LoVerde
Published 2015-01-01

Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment.

by Frédéric D Chevalier, Winka Le Clec'h, Marina McDew-White, Vinay Menon, Meghan A Guzman, Stephen P Holloway, Xiaohang Cao, Alexander B Taylor, Safari Kinung'hi, Anouk N Gouvras, Bonnie L Webster, Joanne P Webster, Aidan M Emery, David Rollinson, Amadou Garba Djirmay, Khalid M Al Mashikhi, Salem Al Yafae, Mohamed A Idris, Hélène Moné, Gabriel Mouahid, P John Hart, Philip T LoVerde, Timothy J C Anderson
Published 2019-10-01