Targeted Treatment of Head and Neck (Pre)Cancer: Preclinical Target Identification and Development of Novel Therapeutic Applications

by Anne M. van Harten, Ruud H. Brakenhoff
Published 2021-06-01

Resection Margins in Head and Neck Cancer Surgery: An Update of Residual Disease and Field Cancerization

by Annouk S. Pierik, C. René Leemans, Ruud H. Brakenhoff
Published 2021-05-01

No Evidence for FANCF Gene Silencing in Head-and-Neck Squamous Cell Carcinomas

by Najim Ameziane, Fei Chen, C. René Leemans, Ruud H. Brakenhoff, Hans Joenje
Published 2009-01-01

Improved high-dimensional prediction with Random Forests by the use of co-data

by Dennis E. te Beest, Steven W. Mes, Saskia M. Wilting, Ruud H. Brakenhoff, Mark A. van de Wiel
Published 2017-12-01

Genetic Classification of Oral and Oropharyngeal Carcinomas Identifies Subgroups with a Different Prognosis

by Serge J. Smeets, Ruud H. Brakenhoff, Bauke Ylstrab, Wessel N. van Wieringen, Mark A. van de Wiel, C. René Leemans, Boudewijn J. M. Braakhuis
Published 2009-01-01

Molecular Detection of Minimal Residual Cancer in Surgical Margins of Head and Neck Cancer Patients

by A. Peggy Graveland, Michiel de Maaker, Boudewijn J. M. Braakhuis, Remco de Bree, Simone E. J. Eerenstein, Elisabeth Bloemena, C. René Leemans, Ruud H. Brakenhoff
Published 2009-01-01

DNA Quality Assessment for Array CGH by Isothermal Whole Genome Amplification

by Tineke E. Buffart, Marianne Tijssen, Thijs Krugers, Beatriz Carvalho, Serge J. Smeets, Ruud H. Brakenhoff, Heike Grabsch, Gerrit A. Meijer, Henry B. Sadowski, Bauke Ylstra
Published 2007-01-01

At the Crossroads of Molecular Biology and Immunology: Molecular Pathways for Immunological Targeting of Head and Neck Squamous Cell Carcinoma

by Niels E. Wondergem, Dennis N. L. M. Nijenhuis, Jos B. Poell, C. René Leemans, Ruud H. Brakenhoff, Rieneke van de Ven, Rieneke van de Ven
Published 2021-03-01

DNA-bound platinum is the major determinant of cisplatin sensitivity in head and neck squamous carcinoma cells.

by Sanne R Martens-de Kemp, Simone U Dalm, Fiona M J Wijnolts, Arjen Brink, Richard J Honeywell, Godefridus J Peters, Boudewijn J M Braakhuis, Ruud H Brakenhoff
Published 2013-01-01

Limited detection of human polyomaviruses in Fanconi anemia related squamous cell carcinoma.

by Tuna Toptan, Marion G Brusadelli, Brian Turpin, David P Witte, Jordi Surrallés, Eunike Velleuer, Martin Schramm, Ralf Dietrich, Ruud H Brakenhoff, Patrick S Moore, Yuan Chang, Susanne I Wells
Published 2018-01-01

Acute Hypoxia Profile is a Stronger Prognostic Factor than Chronic Hypoxia in Advanced Stage Head and Neck Cancer Patients

by Martijn van der Heijden, Monique C. de Jong, Caroline V. M. Verhagen, Reinout H. de Roest, Sebastian Sanduleanu, Frank Hoebers, C. René Leemans, Ruud H. Brakenhoff, Conchita Vens, Marcel Verheij, Michiel W. M. van den Brekel
Published 2019-04-01

Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection

by Costa Bachas, Jasmina Hodzic, Johannes C. van der Mijn, Chantal Stoepker, Henk M. W. Verheul, Rob M. F. Wolthuis, Emanuela Felley-Bosco, Wessel N. van Wieringen, Victor W. van Beusechem, Ruud H. Brakenhoff, Renée X. de Menezes
Published 2018-08-01

Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis af...

by Simon Keek, Sebastian Sanduleanu, Frederik Wesseling, Reinout de Roest, Michiel van den Brekel, Martijn van der Heijden, Conchita Vens, Calareso Giuseppina, Lisa Licitra, Kathrin Scheckenbach, Marije Vergeer, C René Leemans, Ruud H Brakenhoff, Irene Nauta, Stefano Cavalieri, Henry C Woodruff, Tito Poli, Ralph Leijenaar, Frank Hoebers, Philippe Lambin
Published 2020-01-01

Correction: Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant m...

by Simon Keek, Sebastian Sanduleanu, Frederik Wesseling, Reinout de Roest, Michiel van den Brekel, Martijn van der Heijden, Conchita Vens, Calareso Giuseppina, Lisa Licitra, Kathrin Scheckenbach, Marije Vergeer, C René Leemans, Ruud H Brakenhoff, Irene Nauta, Stefano Cavalieri, Henry C Woodruff, Tito Poli, Ralph Leijenaar, Frank Hoebers, Philippe Lambin
Published 2020-01-01

A Prospectively Validated Prognostic Model for Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck Based on Radiomics of Computed Tomography Images

by Simon A. Keek, Frederik W. R. Wesseling, Henry C. Woodruff, Janita E. van Timmeren, Irene H. Nauta, Thomas K. Hoffmann, Stefano Cavalieri, Giuseppina Calareso, Sergey Primakov, Ralph T. H. Leijenaar, Lisa Licitra, Marco Ravanelli, Kathrin Scheckenbach, Tito Poli, Davide Lanfranco, Marije R. Vergeer, C. René Leemans, Ruud H. Brakenhoff, Frank J. P. Hoebers, Philippe Lambin
Published 2021-06-01

Biological Determinants of Chemo-Radiotherapy Response in HPV-Negative Head and Neck Cancer: A Multicentric External Validation

by Martijn van der Heijden, Martijn van der Heijden, Paul B. M. Essers, Paul B. M. Essers, Monique C. de Jong, Reinout H. de Roest, Sebastian Sanduleanu, Caroline V. M. Verhagen, Caroline V. M. Verhagen, Olga Hamming-Vrieze, Frank Hoebers, Philippe Lambin, Harry Bartelink, C. René Leemans, Marcel Verheij, Marcel Verheij, Marcel Verheij, Ruud H. Brakenhoff, Michiel W. M. van den Brekel, Michiel W. M. van den Brekel, Conchita Vens, Conchita Vens
Published 2020-01-01

DPHL: A DIA Pan-human Protein Mass Spectrometry Library for Robust Biomarker Discovery

by Tiansheng Zhu, Yi Zhu, Yue Xuan, Huanhuan Gao, Xue Cai, Sander R. Piersma, Thang V. Pham, Tim Schelfhorst, Richard R.G.D. Haas, Irene V. Bijnsdorp, Rui Sun, Liang Yue, Guan Ruan, Qiushi Zhang, Mo Hu, Yue Zhou, Winan J. Van Houdt, Tessa Y.S. Le Large, Jacqueline Cloos, Anna Wojtuszkiewicz, Danijela Koppers-Lalic, Franziska Böttger, Chantal Scheepbouwer, Ruud H. Brakenhoff, Geert J.L.H. van Leenders, Jan N.M. Ijzermans, John W.M. Martens, Renske D.M. Steenbergen, Nicole C. Grieken, Sathiyamoorthy Selvarajan, Sangeeta Mantoo, Sze S. Lee, Serene J.Y. Yeow, Syed M.F. Alkaff, Nan Xiang, Yaoting Sun, Xiao Yi, Shaozheng Dai, Wei Liu, Tian Lu, Zhicheng Wu, Xiao Liang, Man Wang, Yingkuan Shao, Xi Zheng, Kailun Xu, Qin Yang, Yifan Meng, Cong Lu, Jiang Zhu, Jin'e Zheng, Bo Wang, Sai Lou, Yibei Dai, Chao Xu, Chenhuan Yu, Huazhong Ying, Tony K. Lim, Jianmin Wu, Xiaofei Gao, Zhongzhi Luan, Xiaodong Teng, Peng Wu, Shi'ang Huang, Zhihua Tao, Narayanan G. Iyer, Shuigeng Zhou, Wenguang Shao, Henry Lam, Ding Ma, Jiafu Ji, Oi L. Kon, Shu Zheng, Ruedi Aebersold, Connie R. Jimenez, Tiannan Guo
Published 2020-04-01