Helmsman: fast and efficient mutation signature analysis for massive sequencing datasets

by Jedidiah Carlson, Jun Z. Li, Sebastian Zöllner
Published 2018-11-01

A quantitative comparison of the similarity between genes and geography in worldwide human populations.

by Chaolong Wang, Sebastian Zöllner, Noah A Rosenberg
Published 2012-08-01

Towards colloidal spintronics through Rashba spin-orbit interaction in lead sulphide nanosheets

by Mohammad Mehdi Ramin Moayed, Thomas Bielewicz, Martin Sebastian Zöllner, Carmen Herrmann, Christian Klinke
Published 2017-06-01

Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans

by Jedidiah Carlson, Adam E. Locke, Matthew Flickinger, Matthew Zawistowski, Shawn Levy, Richard M. Myers, Michael Boehnke, Hyun Min Kang, Laura J. Scott, Jun Z. Li, Sebastian Zöllner, The BRIDGES Consortium
Published 2018-09-01

Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes.

by Erin N Smith, Daniel L Koller, Corrie Panganiban, Szabolcs Szelinger, Peng Zhang, Judith A Badner, Thomas B Barrett, Wade H Berrettini, Cinnamon S Bloss, William Byerley, William Coryell, Howard J Edenberg, Tatiana Foroud, Elliot S Gershon, Tiffany A Greenwood, Yiran Guo, Maria Hipolito, Brendan J Keating, William B Lawson, Chunyu Liu, Pamela B Mahon, Melvin G McInnis, Francis J McMahon, Rebecca McKinney, Sarah S Murray, Caroline M Nievergelt, John I Nurnberger, Evaristus A Nwulia, James B Potash, John Rice, Thomas G Schulze, William A Scheftner, Paul D Shilling, Peter P Zandi, Sebastian Zöllner, David W Craig, Nicholas J Schork, John R Kelsoe
Published 2011-06-01

Detecting significant genotype–phenotype association rules in bipolar disorder: market research meets complex genetics

by René Breuer, Manuel Mattheisen, Josef Frank, Bertram Krumm, Jens Treutlein, Layla Kassem, Jana Strohmaier, Stefan Herms, Thomas W. Mühleisen, Franziska Degenhardt, Sven Cichon, Markus M. Nöthen, George Karypis, John Kelsoe, Tiffany Greenwood, Caroline Nievergelt, Paul Shilling, Tatyana Shekhtman, Howard Edenberg, David Craig, Szabolcs Szelinger, John Nurnberger, Elliot Gershon, Ney Alliey-Rodriguez, Peter Zandi, Fernando Goes, Nicholas Schork, Erin Smith, Daniel Koller, Peng Zhang, Judith Badner, Wade Berrettini, Cinnamon Bloss, William Byerley, William Coryell, Tatiana Foroud, Yirin Guo, Maria Hipolito, Brendan Keating, William Lawson, Chunyu Liu, Pamela Mahon, Melvin McInnis, Sarah Murray, Evaristus Nwulia, James Potash, John Rice, William Scheftner, Sebastian Zöllner, Francis J. McMahon, Marcella Rietschel, Thomas G. Schulze
Published 2018-11-01

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixe...

by Madeline H Kowalski, Huijun Qian, Ziyi Hou, Jonathan D Rosen, Amanda L Tapia, Yue Shan, Deepti Jain, Maria Argos, Donna K Arnett, Christy Avery, Kathleen C Barnes, Lewis C Becker, Stephanie A Bien, Joshua C Bis, John Blangero, Eric Boerwinkle, Donald W Bowden, Steve Buyske, Jianwen Cai, Michael H Cho, Seung Hoan Choi, Hélène Choquet, L Adrienne Cupples, Mary Cushman, Michelle Daya, Paul S de Vries, Patrick T Ellinor, Nauder Faraday, Myriam Fornage, Stacey Gabriel, Santhi K Ganesh, Misa Graff, Namrata Gupta, Jiang He, Susan R Heckbert, Bertha Hidalgo, Chani J Hodonsky, Marguerite R Irvin, Andrew D Johnson, Eric Jorgenson, Robert Kaplan, Sharon L R Kardia, Tanika N Kelly, Charles Kooperberg, Jessica A Lasky-Su, Ruth J F Loos, Steven A Lubitz, Rasika A Mathias, Caitlin P McHugh, Courtney Montgomery, Jee-Young Moon, Alanna C Morrison, Nicholette D Palmer, Nathan Pankratz, George J Papanicolaou, Juan M Peralta, Patricia A Peyser, Stephen S Rich, Jerome I Rotter, Edwin K Silverman, Jennifer A Smith, Nicholas L Smith, Kent D Taylor, Timothy A Thornton, Hemant K Tiwari, Russell P Tracy, Tao Wang, Scott T Weiss, Lu-Chen Weng, Kerri L Wiggins, James G Wilson, Lisa R Yanek, Sebastian Zöllner, Kari E North, Paul L Auer, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Hematology & Hemostasis Working Group, Laura M Raffield, Alexander P Reiner, Yun Li
Published 2019-12-01

Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease

by Jonas B. Nielsen, Oren Rom, Ida Surakka, Sarah E. Graham, Wei Zhou, Tanmoy Roychowdhury, Lars G. Fritsche, Sarah A. Gagliano Taliun, Carlo Sidore, Yuhao Liu, Maiken E. Gabrielsen, Anne Heidi Skogholt, Brooke Wolford, William Overton, Ying Zhao, Jin Chen, He Zhang, Whitney E. Hornsby, Akua Acheampong, Austen Grooms, Amanda Schaefer, Gregory J. M. Zajac, Luis Villacorta, Jifeng Zhang, Ben Brumpton, Mari Løset, Vivek Rai, Pia R. Lundegaard, Morten S. Olesen, Kent D. Taylor, Nicholette D. Palmer, Yii-Der Chen, Seung H. Choi, Steven A. Lubitz, Patrick T. Ellinor, Kathleen C. Barnes, Michelle Daya, Nicholas Rafaels, Scott T. Weiss, Jessica Lasky-Su, Russell P. Tracy, Ramachandran S. Vasan, L. Adrienne Cupples, Rasika A. Mathias, Lisa R. Yanek, Lewis C. Becker, Patricia A. Peyser, Lawrence F. Bielak, Jennifer A. Smith, Stella Aslibekyan, Bertha A. Hidalgo, Donna K. Arnett, Marguerite R. Irvin, James G. Wilson, Solomon K. Musani, Adolfo Correa, Stephen S. Rich, Xiuqing Guo, Jerome I. Rotter, Barbara A. Konkle, Jill M. Johnsen, Allison E. Ashley-Koch, Marilyn J. Telen, Vivien A. Sheehan, John Blangero, Joanne E. Curran, Juan M. Peralta, Courtney Montgomery, Wayne H-H Sheu, Ren-Hua Chung, Karen Schwander, Seyed M. Nouraie, Victor R. Gordeuk, Yingze Zhang, Charles Kooperberg, Alexander P. Reiner, Rebecca D. Jackson, Eugene R. Bleecker, Deborah A. Meyers, Xingnan Li, Sayantan Das, Ketian Yu, Jonathon LeFaive, Albert Smith, Tom Blackwell, Daniel Taliun, Sebastian Zollner, Lukas Forer, Sebastian Schoenherr, Christian Fuchsberger, Anita Pandit, Matthew Zawistowski, Sachin Kheterpal, Chad M. Brummett, Pradeep Natarajan, David Schlessinger, Seunggeun Lee, Hyun Min Kang, Francesco Cucca, Oddgeir L. Holmen, Bjørn O. Åsvold, Michael Boehnke, Sekar Kathiresan, Goncalo R. Abecasis, Y. Eugene Chen, Cristen J. Willer, Kristian Hveem
Published 2020-12-01

Genetic Overlap Between Alzheimer’s Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes

by Ole Kristian Drange, Ole Kristian Drange, Olav Bjerkehagen Smeland, Olav Bjerkehagen Smeland, Alexey A. Shadrin, Per Ivar Finseth, Aree Witoelar, Aree Witoelar, Oleksandr Frei, Psychiatric Genomics Consortium Bipolar Disorder Working Group, Yunpeng Wang, Yunpeng Wang, Sahar Hassani, Sahar Hassani, Srdjan Djurovic, Srdjan Djurovic, Anders M. Dale, Anders M. Dale, Anders M. Dale, Ole A. Andreassen, Ole A. Andreassen, Eli A Stahl, Eli A Stahl, Eli A Stahl, Eli A Stahl, Gerome Breen, Gerome Breen, Gerome Breen, Andreas J Forstner, Andreas J Forstner, Andreas J Forstner, Andreas J Forstner, Andreas J Forstner, Andreas J Forstner, Andrew McQuillin, Andrew McQuillin, Stephan Ripke, Stephan Ripke, Stephan Ripke, Stephan Ripke, Vassily Trubetskoy, Manuel Mattheisen, Manuel Mattheisen, Manuel Mattheisen, Manuel Mattheisen, Manuel Mattheisen, Yunpeng Wang, Yunpeng Wang, Jonathan R I Coleman, Jonathan R I Coleman, Heìleìna A Gaspar, Heìleìna A Gaspar, Christiaan A de Leeuw, Stacy Steinberg, Jennifer M Whitehead Pavlides, Maciej Trzaskowski, Tune H Pers, Tune H Pers, Peter A Holmans, Liam Abbott, Esben Agerbo, Esben Agerbo, Esben Agerbo, Huda Akil, Diego Albani, Ney Alliey-Rodriguez, Thomas D Als, Thomas D Als, Thomas D Als, Adebayo Anjorin, Verneri Antilla, Swapnil Awasthi, Judith A Badner, Marie Bækvad-Hansen, Marie Bækvad-Hansen, Jack D Barchas, Nicholas Bass, Michael Bauer, Richard Belliveau, Sarah E Bergen, Carsten Bøcker Pedersen, Carsten Bøcker Pedersen, Carsten Bøcker Pedersen, Erlend Bøen, Marco Boks, James Boocock, Monika Budde, William Bunney, Margit Burmeister, Jonas Bybjerg-Grauholm, Jonas Bybjerg-Grauholm, William Byerley, Miquel Casas, Miquel Casas, Miquel Casas, Miquel Casas, Felecia Cerrato, Pablo Cervantes, Kimberly Chambert, Alexander W Charney, Danfeng Chen, Claire Churchhouse, Claire Churchhouse, Toni-Kim Clarke, William Coryell, David W Craig, Cristiana Cruceanu, Cristiana Cruceanu, David Curtis, David Curtis, Piotr M Czerski, Anders M Dale, Anders M Dale, Anders M Dale, Anders M Dale, Simone de Jong, Simone de Jong, Franziska Degenhardt, Franziska Degenhardt, Jurgen Del-Favero, J Raymond DePaulo, Srdjan Djurovic, Srdjan Djurovic, Amanda L Dobbyn, Amanda L Dobbyn, Ashley Dumont, Torbjørn Elvsåshagen, Torbjørn Elvsåshagen, Valentina Escott-Price, Chun Chieh Fan, Sascha B Fischer, Sascha B Fischer, Matthew Flickinger, Tatiana M Foroud, Liz Forty, Josef Frank, Christine Fraser, Nelson B Freimer, Louise Friseìn, Louise Friseìn, Louise Friseìn, Katrin Gade, Katrin Gade, Diane Gage, Julie Garnham, Claudia Giambartolomei, Marianne Giørtz Pedersen, Marianne Giørtz Pedersen, Marianne Giørtz Pedersen, Jaqueline Goldstein, Scott D Gordon, Katherine Gordon-Smith, Elaine K Green, Melissa J Green, Tiffany A Greenwood, Jakob Grove, Jakob Grove, Jakob Grove, Jakob Grove, Weihua Guan, Joseì Guzman Parra, Marian L Hamshere, Martin Hautzinger, Urs Heilbronner, Stefan Herms, Stefan Herms, Stefan Herms, Stefan Herms, Maria Hipolito, Per Hoffmann, Per Hoffmann, Per Hoffmann, Per Hoffmann, Dominic Holland, Dominic Holland, Laura Huckins, Laura Huckins, Steìphane Jamain, Steìphane Jamain, Jessica S Johnson, Jessica S Johnson, Anders Jureìus, Radhika Kandaswamy, Robert Karlsson, James L Kennedy, James L Kennedy, James L Kennedy, James L Kennedy, Sarah Kittel-Schneider, Sarah V Knott, James A Knowles, James A Knowles, Manolis Kogevinas, Anna C Koller, Anna C Koller, Ralph Kupka, Ralph Kupka, Ralph Kupka, Catharina Lavebratt, Jacob Lawrence, William B Lawson, Markus Leber, Phil H Lee, Phil H Lee, Phil H Lee, Shawn E Levy, Jun Z Li, Chunyu Liu, Susanne Lucae, Anna Maaser, Anna Maaser, Donald J MacIntyre, Donald J MacIntyre, Pamela B Mahon, Pamela B Mahon, Wolfgang Maier, Lina Martinsson, Steve McCarroll, Steve McCarroll, Peter McGuffin, Melvin G McInnis, James D McKay, Helena Medeiros, Sarah E Medland, Fan Meng, Fan Meng, Lili Milani, Grant W Montgomery, Derek W Morris, Derek W Morris, Thomas W Mühleisen, Thomas W Mühleisen, Niamh Mullins, Hoang Nguyen, Hoang Nguyen, Caroline M Nievergelt, Caroline M Nievergelt, Annelie Nordin Adolfsson, Evaristus A Nwulia, Claire O’Donovan, Loes M Olde Loohuis, Anil P S Ori, Lilijana Oruc, Urban Ösby, Roy H Perlis, Roy H Perlis, Amy Perry, Andrea Pfennig, James B Potash, Shaun M Purcell, Shaun M Purcell, Eline J Regeer, Andreas Reif, Ceìline S Reinbold, Ceìline S Reinbold, John P Rice, Fabio Rivas, Margarita Rivera, Margarita Rivera, Panos Roussos, Panos Roussos, Panos Roussos, Douglas M Ruderfer, Euijung Ryu, Cristina Saìnchez-Mora, Cristina Saìnchez-Mora, Cristina Saìnchez-Mora, Alan F Schatzberg, William A Scheftner, Nicholas J Schork, Cynthia Shannon Weickert, Cynthia Shannon Weickert, Tatyana Shehktman, Paul D Shilling, Engilbert Sigurdsson, Claire Slaney, Olav B Smeland, Olav B Smeland, Olav B Smeland, Janet L Sobell, Christine Søholm Hansen, Christine Søholm Hansen, Anne T Spijker, David St Clair, Michael Steffens, John S Strauss, John S Strauss, Fabian Streit, Jana Strohmaier, Szabolcs Szelinger, Robert C Thompson, Thorgeir E Thorgeirsson, Jens Treutlein, Helmut Vedder, Weiqing Wang, Weiqing Wang, Stanley J Watson, Thomas W Weickert, Thomas W Weickert, Stephanie H Witt, Simon Xi, Wei Xu, Wei Xu, Allan H Young, Peter Zandi, Peng Zhang, Sebastian Zollner, Rolf Adolfsson, Ingrid Agartz, Ingrid Agartz, Ingrid Agartz, Martin Alda, Martin Alda, Lena Backlund, Bernhard T Baune, Frank Bellivier, Frank Bellivier, Frank Bellivier, Frank Bellivier, Wade H Berrettini, Joanna M Biernacka, Douglas H R Blackwood, Michael Boehnke, Anders D Børglum, Anders D Børglum, Anders D Børglum, Aiden Corvin, Nicholas Craddock, Mark J Daly, Mark J Daly, Udo Dannlowski, ToÞnu Esko, ToÞnu Esko, ToÞnu Esko, ToÞnu Esko, Bruno Etain, Bruno Etain, Bruno Etain, Bruno Etain, Mark Frye, Janice M Fullerton, Janice M Fullerton, Elliot S Gershon, Elliot S Gershon, Michael Gill, Fernando Goes, Maria Grigoroiu-Serbanescu, Joanna Hauser, David M Hougaard, David M Hougaard, Christina M Hultman, Ian Jones, Lisa A Jones, Reneì S Kahn, Reneì S Kahn, George Kirov, Mikael Landeìn, Mikael Landeìn, Marion Leboyer, Marion Leboyer, Marion Leboyer, Cathryn M Lewis, Cathryn M Lewis, Cathryn M Lewis, Qingqin S Li, Jolanta Lissowska, Nicholas G Martin, Nicholas G Martin, Fermin Mayoral, Susan L McElroy, Andrew M McIntosh, Andrew M McIntosh, Francis J McMahon, Ingrid Melle, Ingrid Melle, Andres Metspalu, Andres Metspalu, Philip B Mitchell, Gunnar Morken, Gunnar Morken, Ole Mors, Ole Mors, Preben Bo Mortensen, Preben Bo Mortensen, Preben Bo Mortensen, Preben Bo Mortensen, Bertram Müller-Myhsok, Bertram Müller-Myhsok, Bertram Müller-Myhsok, Richard M Myers, Benjamin M Neale, Benjamin M Neale, Benjamin M Neale, Vishwajit Nimgaonkar, Merete Nordentoft, Merete Nordentoft, Markus M Nöthen, Markus M Nöthen, Michael C O’Donovan, Ketil J Oedegaard, Ketil J Oedegaard, Michael J Owen, Sara A Paciga, Carlos Pato, Carlos Pato, Michele T Pato, Danielle Posthuma, Danielle Posthuma, Josep Antoni Ramos-Quiroga, Josep Antoni Ramos-Quiroga, Josep Antoni Ramos-Quiroga, Josep Antoni Ramos-Quiroga, Marta Ribaseìs, Marta Ribaseìs, Marta Ribaseìs, Marcella Rietschel, Guy A Rouleau, Guy A Rouleau, Martin Schalling, Peter R Schofield, Peter R Schofield, Thomas G Schulze, Thomas G Schulze, Thomas G Schulze, Thomas G Schulze, Thomas G Schulze, Alessandro Serretti, Jordan W Smoller, Jordan W Smoller, Jordan W Smoller, Hreinn Stefansson, Kari Stefansson, Kari Stefansson, Eystein Stordal, Eystein Stordal, Patrick F Sullivan, Patrick F Sullivan, Patrick F Sullivan, Gustavo Turecki, Arne E Vaaler, Eduard Vieta, John B Vincent, Thomas Werge, Thomas Werge, Thomas Werge, John I Nurnberger, Naomi R Wray, Naomi R Wray, Arianna Di Florio, Arianna Di Florio, Howard J Edenberg, Sven Cichon, Sven Cichon, Sven Cichon, Sven Cichon, Roel A Ophoff, Roel A Ophoff, Roel A Ophoff, Laura J Scott, Ole A Andreassen, Ole A Andreassen, John Kelsoe, John Kelsoe, Pamela Sklar, Pamela Sklar, Pamela Sklar, Pamela Sklar
Published 2019-03-01