Exome analysis of two limb-girdle muscular dystrophy families: mutations identified and challenges encountered.

by Kristin K McDonald, Jeffrey Stajich, Colette Blach, Allison E Ashley-Koch, Michael A Hauser
Published 2012-01-01

Phase 1 Study of a Sulforaphane-Containing Broccoli Sprout Homogenate for Sickle Cell Disease.

by Jennifer F Doss, Jude C Jonassaint, Melanie E Garrett, Allison E Ashley-Koch, Marilyn J Telen, Jen-Tsan Chi
Published 2016-01-01

Correction: In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress.

by Blair R Anderson, David N Howell, Karen Soldano, Melanie E Garrett, Nicholas Katsanis, Marilyn J Telen, Erica E Davis, Allison E Ashley-Koch
Published 2015-09-01

In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress.

by Blair R Anderson, David N Howell, Karen Soldano, Melanie E Garrett, Nicholas Katsanis, Marilyn J Telen, Erica E Davis, Allison E Ashley-Koch
Published 2015-07-01

RNA sequencing of isolated cell populations expressing human APOL1 G2 risk variant reveals molecular correlates of sickle cell nephropathy in zebrafish podocytes.

by Joseph L Bundy, Blair R Anderson, Ludmila Francescatto, Melanie E Garrett, Karen L Soldano, Marilyn J Telen, Erica E Davis, Allison E Ashley-Koch
Published 2019-01-01

Serum albumin is independently associated with higher mortality in adult sickle cell patients: Results of three independent cohorts.

by Mehdi Nouraie, Allison E Ashley-Koch, Melanie E Garrett, Nithya Sritharan, Yingze Zhang, Jane Little, Victor R Gordeuk, Mark T Gladwin, Marilyn J Telen, Gregory J Kato
Published 2020-01-01

Stratified whole genome linkage analysis of Chiari type I malformation implicates known Klippel-Feil syndrome genes as putative disease candidates.

by Christina A Markunas, Karen Soldano, Kaitlyn Dunlap, Heidi Cope, Edgar Asiimwe, Jeffrey Stajich, David Enterline, Gerald Grant, Herbert Fuchs, Simon G Gregory, Allison E Ashley-Koch
Published 2013-01-01

An examination of the association between 5-HTTLPR, combat exposure, and PTSD diagnosis among U.S. veterans.

by Yutao Liu, Melanie E Garrett, Michelle F Dennis, Kimberly T Green, VA Mid-Atlantic MIRECC Registry Workgroup, Allison E Ashley-Koch, Michael A Hauser, Jean C Beckham, Nathan A Kimbrel
Published 2015-01-01

Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer’s disease brains

by Julio Barrera, Lingyun Song, Julia E. Gamache, Melanie E. Garrett, Alexias Safi, Young Yun, Ivana Premasinghe, Daniel Sprague, Danielle Chipman, Jeffrey Li, Hélène Fradin, Karen Soldano, Raluca Gordân, Allison E. Ashley-Koch, Gregory E. Crawford, Ornit Chiba-Falek
Published 2021-08-01

PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia

by Tanner O. Monroe, Melanie E. Garrett, Maria Kousi, Ramona M. Rodriguiz, Sungjin Moon, Yushi Bai, Steven C. Brodar, Karen L. Soldano, Jeremiah Savage, Thomas F. Hansen, Donna M. Muzny, Richard A. Gibbs, Lawrence Barak, Patrick F. Sullivan, Allison E. Ashley-Koch, Akira Sawa, William C. Wetsel, Thomas Werge, Nicholas Katsanis
Published 2020-11-01

Genetic predictors of hippocampal subfield volume in PTSD cases and trauma-exposed controls

by Rajendra A. Morey, Melanie E. Garrett, Jennifer S. Stevens, Emily K. Clarke, Courtney C. Haswell, Sanne J.H. van Rooij, Negar Fani, Adriana Lori, Va Mid-Atlantic Mirecc Workgroup, Nathan A. Kimbrel, Michelle F. Dennis, Christine E. Marx, Jean C. Beckham, Gregory McCarthy, Michael A. Hauser, Allison E. Ashley-Koch
Published 2020-12-01

Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR

by Alicia K. Smith, Andrew Ratanatharathorn, Adam X. Maihofer, Robert K. Naviaux, Allison E. Aiello, Ananda B. Amstadter, Allison E. Ashley-Koch, Dewleen G. Baker, Jean C. Beckham, Marco P. Boks, Evelyn Bromet, Michelle Dennis, Sandro Galea, Melanie E. Garrett, Elbert Geuze, Guia Guffanti, Michael A. Hauser, Seyma Katrinli, Varun Kilaru, Ronald C. Kessler, Nathan A. Kimbrel, Karestan C. Koenen, Pei-Fen Kuan, Kefeng Li, Mark W. Logue, Adriana Lori, Benjamin J. Luft, Mark W. Miller, Jane C. Naviaux, Nicole R. Nugent, Xuejun Qin, Kerry J. Ressler, Victoria B. Risbrough, Bart P. F. Rutten, Murray B. Stein, Robert J. Ursano, Eric Vermetten, Christiaan H. Vinkers, Lin Wang, Nagy A. Youssef, INTRuST Clinical Consortium, VA Mid-Atlantic MIRECC Workgroup, PGC PTSD Epigenetics Workgroup, Monica Uddin, Caroline M. Nievergelt
Published 2020-11-01

Gene Expression Analysis in Three Posttraumatic Stress Disorder Cohorts Implicates Inflammation and Innate Immunity Pathways and Uncovers Shared Genetic Risk With Major Depressive...

by Melanie E. Garrett, Xue Jun Qin, Divya Mehta, Michelle F. Dennis, Michelle F. Dennis, Michelle F. Dennis, Christine E. Marx, Christine E. Marx, Christine E. Marx, Gerald A. Grant, VA Mid-Atlantic MIRECC Workgroup, PTSD Initiative, PTSD Initiative, Injury and Traumatic Stress (INTRuST) Clinical Consortium, Psychiatric Genomics Consortium PTSD Group, Murray B. Stein, Murray B. Stein, Murray B. Stein, Nathan A. Kimbrel, Nathan A. Kimbrel, Nathan A. Kimbrel, Jean C. Beckham, Jean C. Beckham, Jean C. Beckham, Michael A. Hauser, Allison E. Ashley-Koch, Mira Brancu, Patrick S. Calhoun, Eric Dedert, Eric B. Elbogen, John A. Fairbank, Robin A. Hurley, Jason D. Kilts, Angela Kirby, Sara Martindale, Scott D. McDonald, Scott D. Moore, Rajendra A. Morey, Jennifer C. Naylor, Jared Rowland, Robert Shura, Cindy Swinkels, Steven T. Szabo, Katherine H. Taber, Larry A. Tupler, Ruth E. Yoash-Gantz, Sarah McLeay, Wendy Harvey, Madeline Romaniuk, Darrell Crawford, David Colquhoun, Ross McD Young, Miriam Dwyer, John Gibson, Robyn O’Sullivan, Graham Cooksley, Christopher Strakosch, Rachel Thomson, Joanne Voisey, Bruce Lawford
Published 2021-07-01

Examining Individual and Synergistic Contributions of PTSD and Genetics to Blood Pressure: A Trans-Ethnic Meta-Analysis

by Jennifer A. Sumner, Adam X. Maihofer, Adam X. Maihofer, Vasiliki Michopoulos, Vasiliki Michopoulos, Alex O. Rothbaum, Lynn M. Almli, Ole A. Andreassen, Ole A. Andreassen, Allison E. Ashley-Koch, Dewleen G. Baker, Dewleen G. Baker, Jean C. Beckham, Jean C. Beckham, Jean C. Beckham, Bekh Bradley, Bekh Bradley, Gerome Breen, Gerome Breen, Jonathan R. I. Coleman, Jonathan R. I. Coleman, Anders M. Dale, Anders M. Dale, Michelle F. Dennis, Michelle F. Dennis, Michelle F. Dennis, Norah C. Feeny, Carol E. Franz, Melanie E. Garrett, Charles F. Gillespie, Guia Guffanti, Guia Guffanti, Michael A. Hauser, Sian M. J. Hemmings, Sian M. J. Hemmings, Tanja Jovanovic, Nathan A. Kimbrel, Nathan A. Kimbrel, Nathan A. Kimbrel, William S. Kremen, William S. Kremen, Bruce R. Lawford, Mark W. Logue, Mark W. Logue, Mark W. Logue, Mark W. Logue, Adriana Lori, Michael J. Lyons, Jessica Maples-Keller, Matig R. Mavissakalian, Regina E. McGlinchey, Divya Mehta, Rebecca Mellor, William Milberg, Mark W. Miller, Mark W. Miller, Charles Phillip Morris, Matthew S. Panizzon, Kerry J. Ressler, Kerry J. Ressler, Kerry J. Ressler, Victoria B. Risbrough, Victoria B. Risbrough, Barbara O. Rothbaum, Peter Roy-Byrne, Soraya Seedat, Soraya Seedat, Alicia K. Smith, Alicia K. Smith, Jennifer S. Stevens, Leigh Luella van den Heuvel, Leigh Luella van den Heuvel, Joanne Voisey, Joanne Voisey, Ross McD Young, Lori A. Zoellner, Caroline M. Nievergelt, Caroline M. Nievergelt, Erika J. Wolf, Erika J. Wolf
Published 2021-06-01

Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease

by Jonas B. Nielsen, Oren Rom, Ida Surakka, Sarah E. Graham, Wei Zhou, Tanmoy Roychowdhury, Lars G. Fritsche, Sarah A. Gagliano Taliun, Carlo Sidore, Yuhao Liu, Maiken E. Gabrielsen, Anne Heidi Skogholt, Brooke Wolford, William Overton, Ying Zhao, Jin Chen, He Zhang, Whitney E. Hornsby, Akua Acheampong, Austen Grooms, Amanda Schaefer, Gregory J. M. Zajac, Luis Villacorta, Jifeng Zhang, Ben Brumpton, Mari Løset, Vivek Rai, Pia R. Lundegaard, Morten S. Olesen, Kent D. Taylor, Nicholette D. Palmer, Yii-Der Chen, Seung H. Choi, Steven A. Lubitz, Patrick T. Ellinor, Kathleen C. Barnes, Michelle Daya, Nicholas Rafaels, Scott T. Weiss, Jessica Lasky-Su, Russell P. Tracy, Ramachandran S. Vasan, L. Adrienne Cupples, Rasika A. Mathias, Lisa R. Yanek, Lewis C. Becker, Patricia A. Peyser, Lawrence F. Bielak, Jennifer A. Smith, Stella Aslibekyan, Bertha A. Hidalgo, Donna K. Arnett, Marguerite R. Irvin, James G. Wilson, Solomon K. Musani, Adolfo Correa, Stephen S. Rich, Xiuqing Guo, Jerome I. Rotter, Barbara A. Konkle, Jill M. Johnsen, Allison E. Ashley-Koch, Marilyn J. Telen, Vivien A. Sheehan, John Blangero, Joanne E. Curran, Juan M. Peralta, Courtney Montgomery, Wayne H-H Sheu, Ren-Hua Chung, Karen Schwander, Seyed M. Nouraie, Victor R. Gordeuk, Yingze Zhang, Charles Kooperberg, Alexander P. Reiner, Rebecca D. Jackson, Eugene R. Bleecker, Deborah A. Meyers, Xingnan Li, Sayantan Das, Ketian Yu, Jonathon LeFaive, Albert Smith, Tom Blackwell, Daniel Taliun, Sebastian Zollner, Lukas Forer, Sebastian Schoenherr, Christian Fuchsberger, Anita Pandit, Matthew Zawistowski, Sachin Kheterpal, Chad M. Brummett, Pradeep Natarajan, David Schlessinger, Seunggeun Lee, Hyun Min Kang, Francesco Cucca, Oddgeir L. Holmen, Bjørn O. Åsvold, Michael Boehnke, Sekar Kathiresan, Goncalo R. Abecasis, Y. Eugene Chen, Cristen J. Willer, Kristian Hveem
Published 2020-12-01

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

by Caroline M. Nievergelt, Adam X. Maihofer, Torsten Klengel, Elizabeth G. Atkinson, Chia-Yen Chen, Karmel W. Choi, Jonathan R. I. Coleman, Shareefa Dalvie, Laramie E. Duncan, Joel Gelernter, Daniel F. Levey, Mark W. Logue, Renato Polimanti, Allison C. Provost, Andrew Ratanatharathorn, Murray B. Stein, Katy Torres, Allison E. Aiello, Lynn M. Almli, Ananda B. Amstadter, Søren B. Andersen, Ole A. Andreassen, Paul A. Arbisi, Allison E. Ashley-Koch, S. Bryn Austin, Esmina Avdibegovic, Dragan Babić, Marie Bækvad-Hansen, Dewleen G. Baker, Jean C. Beckham, Laura J. Bierut, Jonathan I. Bisson, Marco P. Boks, Elizabeth A. Bolger, Anders D. Børglum, Bekh Bradley, Megan Brashear, Gerome Breen, Richard A. Bryant, Angela C. Bustamante, Jonas Bybjerg-Grauholm, Joseph R. Calabrese, José M. Caldas- de- Almeida, Anders M. Dale, Mark J. Daly, Nikolaos P. Daskalakis, Jürgen Deckert, Douglas L. Delahanty, Michelle F. Dennis, Seth G. Disner, Katharina Domschke, Alma Dzubur-Kulenovic, Christopher R. Erbes, Alexandra Evans, Lindsay A. Farrer, Norah C. Feeny, Janine D. Flory, David Forbes, Carol E. Franz, Sandro Galea, Melanie E. Garrett, Bizu Gelaye, Elbert Geuze, Charles Gillespie, Aferdita Goci Uka, Scott D. Gordon, Guia Guffanti, Rasha Hammamieh, Supriya Harnal, Michael A. Hauser, Andrew C. Heath, Sian M. J. Hemmings, David Michael Hougaard, Miro Jakovljevic, Marti Jett, Eric Otto Johnson, Ian Jones, Tanja Jovanovic, Xue-Jun Qin, Angela G. Junglen, Karen-Inge Karstoft, Milissa L. Kaufman, Ronald C. Kessler, Alaptagin Khan, Nathan A. Kimbrel, Anthony P. King, Nastassja Koen, Henry R. Kranzler, William S. Kremen, Bruce R. Lawford, Lauren A. M. Lebois, Catrin E. Lewis, Sarah D. Linnstaedt, Adriana Lori, Bozo Lugonja, Jurjen J. Luykx, Michael J. Lyons, Jessica Maples-Keller, Charles Marmar, Alicia R. Martin, Nicholas G. Martin, Douglas Maurer, Matig R. Mavissakalian, Alexander McFarlane, Regina E. McGlinchey, Katie A. McLaughlin, Samuel A. McLean, Sarah McLeay, Divya Mehta, William P. Milberg, Mark W. Miller, Rajendra A. Morey, Charles Phillip Morris, Ole Mors, Preben B. Mortensen, Benjamin M. Neale, Elliot C. Nelson, Merete Nordentoft, Sonya B. Norman, Meaghan O’Donnell, Holly K. Orcutt, Matthew S. Panizzon, Edward S. Peters, Alan L. Peterson, Matthew Peverill, Robert H. Pietrzak, Melissa A. Polusny, John P. Rice, Stephan Ripke, Victoria B. Risbrough, Andrea L. Roberts, Alex O. Rothbaum, Barbara O. Rothbaum, Peter Roy-Byrne, Ken Ruggiero, Ariane Rung, Bart P. F. Rutten, Nancy L. Saccone, Sixto E. Sanchez, Dick Schijven, Soraya Seedat, Antonia V. Seligowski, Julia S. Seng, Christina M. Sheerin, Derrick Silove, Alicia K. Smith, Jordan W. Smoller, Scott R. Sponheim, Dan J. Stein, Jennifer S. Stevens, Jennifer A. Sumner, Martin H. Teicher, Wesley K. Thompson, Edward Trapido, Monica Uddin, Robert J. Ursano, Leigh Luella van den Heuvel, Miranda Van Hooff, Eric Vermetten, Christiaan H. Vinkers, Joanne Voisey, Yunpeng Wang, Zhewu Wang, Thomas Werge, Michelle A. Williams, Douglas E. Williamson, Sherry Winternitz, Christiane Wolf, Erika J. Wolf, Jonathan D. Wolff, Rachel Yehuda, Ross McD. Young, Keith A. Young, Hongyu Zhao, Lori A. Zoellner, Israel Liberzon, Kerry J. Ressler, Magali Haas, Karestan C. Koenen
Published 2019-10-01