Tumor Targeting and Drug Delivery by Anthrax Toxin

by Christopher Bachran, Stephen H. Leppla
Published 2016-07-01

Anthrax toxin uptake by primary immune cells as determined with a lethal factor-beta-lactamase fusion protein.

by Haijing Hu, Stephen H Leppla
Published 2009-11-01

Characterization of a Chinese hamster ovary cell mutant having a mutation in elongation factor-2.

by Pradeep K Gupta, Shihui Liu, Stephen H Leppla
Published 2010-02-01

Bacterial exotoxins and the inflammasome

by Allison J. Greaney, Stephen H. Leppla, Mahtab eMoayeri
Published 2015-11-01

The Receptors that Mediate the Direct Lethality of Anthrax Toxin

by Stephen H. Leppla, Benjamin Hoover, Yi Zhang, Shihui Liu
Published 2012-12-01

Correction: Broad Expression Analysis of Human ANTXR1/TEM8 Transcripts Reveals Differential Expression and Novel Splizce Variants

by Micaela Vargas, Raghavendra Karamsetty, Stephen H. Leppla, G. Jilani Chaudry
Published 2012-01-01

Broad expression analysis of human ANTXR1/TEM8 transcripts reveals differential expression and novel splizce variants.

by Micaela Vargas, Raghavendra Karamsetty, Stephen H Leppla, G Jilani Chaudry
Published 2012-01-01

Correction: Broad Expression Analysis of Human ANTXR1/TEM8 Transcripts Reveals Differential Expression and Novel Splizce Variants.

by Micaela Vargas, Raghavendra Karamsetty, Stephen H. Leppla, G. Jilani Chaudry
Published 2012-01-01

Role of N-terminal amino acids in the potency of anthrax lethal factor.

by Pradeep K Gupta, Mahtab Moayeri, Devorah Crown, Rasem J Fattah, Stephen H Leppla
Published 2008-09-01

Characterization of the NLRP1 inflammasome response in bovine species

by Catherine E Vrentas, Paola M Boggiatto, Steven C Olsen, Stephen H Leppla, Mahtab Moayeri
Published 2020-05-01

Anthrax edema factor toxicity is strongly mediated by the N-end rule.

by Clinton E Leysath, Damilola D Phillips, Devorah Crown, Rasem J Fattah, Mahtab Moayeri, Stephen H Leppla
Published 2013-01-01

The Bacillus cereus Hbl and Nhe tripartite enterotoxin components assemble sequentially on the surface of target cells and are not interchangeable.

by Inka Sastalla, Rasem Fattah, Nicole Coppage, Poulomi Nandy, Devorah Crown, Andrei P Pomerantsev, Stephen H Leppla
Published 2013-01-01

Genome engineering in Bacillus anthracis using tyrosine site-specific recombinases.

by Andrei P Pomerantsev, Rita M McCall, Margaret Chahoud, Nathan K Hepler, Rasem Fattah, Stephen H Leppla
Published 2017-01-01

Efficient targeting of head and neck squamous cell carcinoma by systemic administration of a dual uPA and MMP-activated engineered anthrax toxin.

by Jeffrey M Schafer, Diane E Peters, Thomas Morley, Shihui Liu, Alfredo A Molinolo, Stephen H Leppla, Thomas H Bugge
Published 2011-01-01

Cytotoxicity of Anthrax Lethal Toxin to Human Acute Myeloid Leukemia Cells Is Nonapoptotic and Dependent on Extracellular Signal-Regulated Kinase 1/2 Activity

by Elias Kassab, Manal Darwish, Zahra Timsah, ShiHui Liu, Stephen H. Leppla, Arthur E. Frankel, Ralph J. Abi-Habib
Published 2013-02-01

Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin

by Laurence Abrami, Lucia Brandi, Mahtab Moayeri, Michael J. Brown, Bryan A. Krantz, Stephen H. Leppla, F. Gisou van der Goot
Published 2013-11-01

Inflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment.

by Mahtab Moayeri, Devorah Crown, Zachary L Newman, Shu Okugawa, Michael Eckhaus, Christophe Cataisson, Shihui Liu, Inka Sastalla, Stephen H Leppla
Published 2010-12-01

A Bacteriophage T4 Nanoparticle-Based Dual Vaccine against Anthrax and Plague

by Pan Tao, Marthandan Mahalingam, Jingen Zhu, Mahtab Moayeri, Jian Sha, William S. Lawrence, Stephen H. Leppla, Ashok K. Chopra, Venigalla B. Rao
Published 2018-10-01

The heart is an early target of anthrax lethal toxin in mice: a protective role for neuronal nitric oxide synthase (nNOS).

by Mahtab Moayeri, Devorah Crown, David W Dorward, Don Gardner, Jerrold M Ward, Yan Li, Xizhong Cui, Peter Eichacker, Stephen H Leppla
Published 2009-05-01

Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1.

by Zachary L Newman, Morton P Printz, Shihui Liu, Devorah Crown, Laura Breen, Sharmina Miller-Randolph, Pamela Flodman, Stephen H Leppla, Mahtab Moayeri
Published 2010-05-01