Germline genetic variation modulates tumor progression and metastasis in a mouse model of neuroendocrine prostate carcinoma.

by Shashank J Patel, Alfredo A Molinolo, Silvio Gutkind, Nigel P S Crawford
Published 2013-01-01

Improved Clearance during Treatment of HPV-Positive Head and Neck Cancer through mTOR Inhibition

by Joseph D. Coppock, Bryant G. Wieking, Alfredo A. Molinolo, J. Silvio Gutkind, W. Keith Miskimins, John H. Lee
Published 2013-06-01

Efficient targeting of head and neck squamous cell carcinoma by systemic administration of a dual uPA and MMP-activated engineered anthrax toxin.

by Jeffrey M Schafer, Diane E Peters, Thomas Morley, Shihui Liu, Alfredo A Molinolo, Stephen H Leppla, Thomas H Bugge
Published 2011-01-01

Toxicological Studies of 212Pb Intravenously or Intraperitoneally Injected into Mice for a Phase 1 Trial

by Diane E. Milenic, Alfredo A. Molinolo, María S. Solivella, Eileen Banaga, Julien Torgue, Sarah Besnainou, Martin W. Brechbiel, Kwamena E. Baidoo
Published 2015-07-01

Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes.

by Colleen L Doçi, Constantinos M Mikelis, Juan Luis Callejas-Valera, Karina K Hansen, Alfredo A Molinolo, Asuka Inoue, Stefan Offermanns, J Silvio Gutkind
Published 2017-01-01

Expression and genetic loss of function analysis of the HAT/DESC cluster proteases TMPRSS11A and HAT.

by Katiuchia Uzzun Sales, John P Hobson, Rebecca Wagenaar-Miller, Roman Szabo, Amber L Rasmussen, Alexandra Bey, Maham F Shah, Alfredo A Molinolo, Thomas H Bugge
Published 2011-01-01

Age-related differences in breast cancer mortality according to race/ethnicity, insurance, and socioeconomic status

by Yazmin San Miguel, Scarlett Lin Gomez, James D. Murphy, Richard B. Schwab, Corinne McDaniels-Davidson, Alison J. Canchola, Alfredo A. Molinolo, Jesse N. Nodora, Maria Elena Martinez
Published 2020-03-01

A systems genetics approach identifies CXCL14, ITGAX, and LPCAT2 as novel aggressive prostate cancer susceptibility genes.

by Kendra A Williams, Minnkyong Lee, Ying Hu, Jonathan Andreas, Shashank J Patel, Suiyuan Zhang, Peter Chines, Abdel Elkahloun, Settara Chandrasekharappa, J Silvio Gutkind, Alfredo A Molinolo, Nigel P S Crawford
Published 2014-11-01

Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing.

by Akihiro Sakai, Mizuo Ando, Takahito Fukusumi, Shuling Ren, Chao Liu, Jesse Qualliotine, Sunny Haft, Sayed Sadat, Yuki Saito, Theresa W Guo, Guorong Xu, Roman Sasik, Kathleen M Fisch, J Silvio Gutkind, Elana J Fertig, Alfredo A Molinolo, Joseph A Califano
Published 2020-01-01

Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer

by Zhiyong Wang, Yusuke Goto, Michael M. Allevato, Victoria H. Wu, Robert Saddawi-Konefka, Mara Gilardi, Diego Alvarado, Bryan S. Yung, Aoife O’Farrell, Alfredo A. Molinolo, Umamaheswar Duvvuri, Jennifer R. Grandis, Joseph A. Califano, Ezra E. W. Cohen, J. Silvio Gutkind
Published 2021-04-01

Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4

by Zhiyong Wang, Victoria H. Wu, Michael M. Allevato, Mara Gilardi, Yudou He, Juan Luis Callejas-Valera, Lynn Vitale-Cross, Daniel Martin, Panomwat Amornphimoltham, James Mcdermott, Bryan S. Yung, Yusuke Goto, Alfredo A. Molinolo, Andrew B. Sharabi, Ezra E. W. Cohen, Qianming Chen, J. Guy Lyons, Ludmil B. Alexandrov, J. Silvio Gutkind
Published 2019-12-01

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor

by Daniel Martin, Maria S. Degese, Lynn Vitale-Cross, Ramiro Iglesias-Bartolome, Juan Luis Callejas Valera, Zhiyong Wang, Xiaodong Feng, Huwate Yeerna, Vachan Vadmal, Toshiro Moroishi, Rick F. Thorne, Moraima Zaida, Bradford Siegele, Sok C. Cheong, Alfredo A. Molinolo, Yardena Samuels, Pablo Tamayo, Kun Liang Guan, Scott M. Lippman, J. Guy Lyons, J. Silvio Gutkind
Published 2018-07-01

Progesterone promotes immunomodulation and tumor development in the murine mammary gland

by Alfredo A Molinolo, Junping Wei, Xiao-Yi Yang, Gangjun Lei, Zachary C Hartman, Lauryn R Werner, Katelin A Gibson, Merit L Goodman, Dominika E Helm, Katherine R Walter, Sean M Holloran, Gloria M Trinca, Richard C Hastings, Howard H Yang, Rashna Madan, Mary A Markiewicz, Prabhakar Chalise, Margaret L Axelrod, Justin M Balko, Kent W Hunter, Carol A Lange, Christy R Hagan
Published 2021-05-01