Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma

by Shelly Kalaora, Joo Sang Lee, Eilon Barnea, Ronen Levy, Polina Greenberg, Michal Alon, Gal Yagel, Gitit Bar Eli, Roni Oren, Aviyah Peri, Sushant Patkar, Lital Bitton, Steven A. Rosenberg, Michal Lotem, Yishai Levin, Arie Admon, Eytan Ruppin, Yardena Samuels
Published 2020-02-01

Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics

by Adi Nagler, Shelly Kalaora, Chaya Barbolin, Anastasia Gangaev, Steven L.C. Ketelaars, Michal Alon, Joy Pai, Gil Benedek, Yfat Yahalom-Ronen, Noam Erez, Polina Greenberg, Gal Yagel, Aviyah Peri, Yishai Levin, Ansuman T. Satpathy, Erez Bar-Haim, Nir Paran, Pia Kvistborg, Yardena Samuels
Published 2021-06-01

Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation

by Hyungsoo Kim, Dennie T. Frederick, Mitchell P. Levesque, Zachary A. Cooper, Yongmei Feng, Clemens Krepler, Laurence Brill, Yardena Samuels, Nicholas K. Hayward, Ally Perlina, Adriano Piris, Tongwu Zhang, Ruth Halaban, Meenhard M. Herlyn, Kevin M. Brown, Jennifer A. Wargo, Reinhard Dummer, Keith T. Flaherty, Ze’ev A. Ronai
Published 2015-06-01

672 Identification of microbial-derived HLA-bound peptides in melanoma

by Yardena Samuels, David Adams, Alexandre Reuben, Jennifer Wargo, Adi Nagler, Shelly Kalaora, Deborah Gitta Rosenberg, Michal Alon, Eilon Barnea, Ronen Levy, Kevin Vervier, Sophie Trabish, Tali Dadosh, Smadar Zaidman, Leore Geller, Polina Greenberg, Neerupma Bhardwaj, Reetakshi Arora, Michal Lotem, Arie Admon, Yishai Levin, Trevor Lawley, Naama Geva-Zatorsky, Ravid Straussman
Published 2020-11-01

Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes.

by Stephen C J Parker, Jared Gartner, Isabel Cardenas-Navia, Xiaomu Wei, Hatice Ozel Abaan, Subramanian S Ajay, Nancy F Hansen, Lingyun Song, Umesh K Bhanot, J Keith Killian, Yevgeniy Gindin, Robert L Walker, Paul S Meltzer, James C Mullikin, Terrence S Furey, Gregory E Crawford, Steven A Rosenberg, Yardena Samuels, Elliott H Margulies
Published 2012-01-01

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor

by Daniel Martin, Maria S. Degese, Lynn Vitale-Cross, Ramiro Iglesias-Bartolome, Juan Luis Callejas Valera, Zhiyong Wang, Xiaodong Feng, Huwate Yeerna, Vachan Vadmal, Toshiro Moroishi, Rick F. Thorne, Moraima Zaida, Bradford Siegele, Sok C. Cheong, Alfredo A. Molinolo, Yardena Samuels, Pablo Tamayo, Kun Liang Guan, Scott M. Lippman, J. Guy Lyons, J. Silvio Gutkind
Published 2018-07-01

Harnessing synthetic lethality to predict the response to cancer treatment

by Joo Sang Lee, Avinash Das, Livnat Jerby-Arnon, Rand Arafeh, Noam Auslander, Matthew Davidson, Lynn McGarry, Daniel James, Arnaud Amzallag, Seung Gu Park, Kuoyuan Cheng, Welles Robinson, Dikla Atias, Chani Stossel, Ella Buzhor, Gidi Stein, Joshua J. Waterfall, Paul S. Meltzer, Talia Golan, Sridhar Hannenhalli, Eyal Gottlieb, Cyril H. Benes, Yardena Samuels, Emma Shanks, Eytan Ruppin
Published 2018-06-01

Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer

by Yujun Hao, Yardena Samuels, Qingling Li, Dawid Krokowski, Bo-Jhih Guan, Chao Wang, Zhicheng Jin, Bohan Dong, Bo Cao, Xiujing Feng, Min Xiang, Claire Xu, Stephen Fink, Neal J. Meropol, Yan Xu, Ronald A. Conlon, Sanford Markowitz, Kenneth W. Kinzler, Victor E. Velculescu, Henri Brunengraber, Joseph E. Willis, Thomas LaFramboise, Maria Hatzoglou, Guo-Fang Zhang, Bert Vogelstein, Zhenghe Wang
Published 2016-06-01