PRMT5 function and targeting in cancer

by Hyungsoo Kim, Ze’ev A. Ronai
Published 2020-07-01

The anaphase-promoting complex or cyclosome supports cell survival in response to endoplasmic reticulum stress.

by Meifan Chen, Gustavo J Gutierrez, Ze'ev A Ronai
Published 2012-01-01

Fine tuning of the UPR by the ubiquitin ligases Siah1/2.

by Marzia Scortegagna, Hyungsoo Kim, Jian-Liang Li, Hang Yao, Laurence M Brill, Jaeseok Han, Eric Lau, David Bowtell, Gabriel Haddad, Randal J Kaufman, Ze'ev A Ronai
Published 2014-05-01

Correction: Two roads for oncolytic immunotherapy development

by Michael Timaner, Ziv Raviv, Shai Shen-Orr, Yuval Shaked, Tongwu Zhang, Ksenia Magidey-Klein, Tim J Cooper, Ksenya Kveler, Rachelly Normand, Brian P. James, Roi Gazit, Ze'ev A. Ronai
Published 2021-06-01

IL-6 contributes to metastatic switch via the differentiation of monocytic-dendritic progenitors into prometastatic immune cells

by Michael Timaner, Ziv Raviv, Shai Shen-Orr, Yuval Shaked, Tongwu Zhang, Ksenia Magidey-Klein, Tim J Cooper, Ksenya Kveler, Rachelly Normand, Brian P. James, Roi Gazit, Ze'ev A. Ronai
Published 2021-06-01

β-Catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors.

by Luca Grumolato, Guizhong Liu, Tomomi Haremaki, Sathish Kumar Mungamuri, Phyllus Mong, Gal Akiri, Pablo Lopez-Bergami, Adriana Arita, Youssef Anouar, Marek Mlodzik, Ze'ev A Ronai, Joshua Brody, Daniel C Weinstein, Stuart A Aaronson
Published 2013-01-01

Siah2 control of T-regulatory cells limits anti-tumor immunity

by Marzia Scortegagna, Kathryn Hockemeyer, Igor Dolgalev, Joanna Poźniak, Florian Rambow, Yan Li, Yongmei Feng, Roberto Tinoco, Dennis C. Otero, Tongwu Zhang, Kevin Brown, Marcus Bosenberg, Linda M. Bradley, Jean-Christophe Marine, Ioannis Aifantis, Ze’ev A. Ronai
Published 2020-01-01

Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth

by Yan Li, Lisa Elmén, Igor Segota, Yibo Xian, Roberto Tinoco, Yongmei Feng, Yu Fujita, Rafael R. Segura Muñoz, Robert Schmaltz, Linda M. Bradley, Amanda Ramer-Tait, Raphy Zarecki, Tao Long, Scott N. Peterson, Ze’ev A. Ronai
Published 2020-02-01

A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis

by Giuseppina Claps, Yann Cheli, Tongwu Zhang, Marzia Scortegagna, Eric Lau, Hyungsoo Kim, Jianfei Qi, Jian-Liang Li, Brian James, Andreas Dzung, Mitchell P. Levesque, Reinhard Dummer, Nicholas K. Hayward, Marcus Bosenberg, Kevin M. Brown, Ze’ev A. Ronai
Published 2016-05-01

Correction: Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection.

by Ersheng Kuang, Cheryl Y M Okumura, Sharon Sheffy-Levin, Tal Varsano, Vincent Chih-Wen Shu, Jianfei Qi, Ingrid R Niesman, Huei-Jiun Yang, Carlos López-Otín, Wei Yuan Yang, John C Reed, Limor Broday, Victor Nizet, Ze'ev A Ronai
Published 2020-05-01

A role for ATF2 in regulating MITF and melanoma development.

by Meera Shah, Anindita Bhoumik, Vikas Goel, Antimone Dewing, Wolfgang Breitwieser, Harriet Kluger, Stan Krajewski, Maryla Krajewska, Jason Dehart, Eric Lau, David M Kallenberg, Hyeongnam Jeong, Alexey Eroshkin, Dorothy C Bennett, Lynda Chin, Marcus Bosenberg, Nic Jones, Ze'ev A Ronai
Published 2010-12-01

Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection.

by Ersheng Kuang, Cheryl Y M Okumura, Sharon Sheffy-Levin, Tal Varsano, Vincent Chih-Wen Shu, Jianfei Qi, Ingrid R Niesman, Huei-Jiun Yang, Carlos López-Otín, Wei Yuan Yang, John C Reed, Limor Broday, Victor Nizet, Ze'ev A Ronai
Published 2012-01-01

Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis

by Yu Fujita, Ali Khateb, Yan Li, Roberto Tinoco, Tongwu Zhang, Haggai Bar-Yoseph, Miguel A. Tam, Yehuda Chowers, Edmond Sabo, Shiran Gerassy-Vainberg, Elina Starosvetsky, Brian James, Kevin Brown, Shai S. Shen-Orr, Linda M. Bradley, Philippe A. Tessier, Ze’ev A. Ronai
Published 2018-09-01

Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation

by Hyungsoo Kim, Dennie T. Frederick, Mitchell P. Levesque, Zachary A. Cooper, Yongmei Feng, Clemens Krepler, Laurence Brill, Yardena Samuels, Nicholas K. Hayward, Ally Perlina, Adriano Piris, Tongwu Zhang, Ruth Halaban, Meenhard M. Herlyn, Kevin M. Brown, Jennifer A. Wargo, Reinhard Dummer, Keith T. Flaherty, Ze’ev A. Ronai
Published 2015-06-01

The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors

by Ali Khateb, Anagha Deshpande, Yongmei Feng, Darren Finlay, Joo Sang Lee, Ikrame Lazar, Bertrand Fabre, Yan Li, Yu Fujita, Tongwu Zhang, Jun Yin, Ian Pass, Ido Livneh, Irmela Jeremias, Carol Burian, James R. Mason, Ronit Almog, Nurit Horesh, Yishai Ofran, Kevin Brown, Kristiina Vuori, Michael Jackson, Eytan Ruppin, Aniruddha J. Deshpande, Ze’ev A. Ronai
Published 2021-09-01

Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 −/− mice

by Yan Li, Roberto Tinoco, Lisa Elmén, Igor Segota, Yibo Xian, Yu Fujita, Avinash Sahu, Raphy Zarecki, Kerrie Marie, Yongmei Feng, Ali Khateb, Dennie T. Frederick, Shiri K. Ashkenazi, Hyungsoo Kim, Eva Guijarro Perez, Chi-Ping Day, Rafael S. Segura Muñoz, Robert Schmaltz, Shibu Yooseph, Miguel A. Tam, Tongwu Zhang, Emily Avitan-Hersh, Lihi Tzur, Shoshana Roizman, Ilanit Boyango, Gil Bar-Sela, Amir Orian, Randal J. Kaufman, Marcus Bosenberg, Colin R. Goding, Bas Baaten, Mitchell P. Levesque, Reinhard Dummer, Kevin Brown, Glenn Merlino, Eytan Ruppin, Keith Flaherty, Amanda Ramer-Tait, Tao Long, Scott N. Peterson, Linda M. Bradley, Ze’ev A. Ronai
Published 2019-04-01