Metabolomics Reveals New Mechanisms for Pathogenesis in Barth Syndrome and Introduces Novel Roles for Cardiolipin in Cellular Function.

by Yana Sandlers, Kelly Mercier, Wimal Pathmasiri, Jim Carlson, Susan McRitchie, Susan Sumner, Hilary J Vernon
Published 2016-01-01

Aldh1l2 knockout mouse metabolomics links the loss of the mitochondrial folate enzyme to deregulation of a lipid metabolism observed in rare human disorder

by Natalia I. Krupenko, Jaspreet Sharma, Peter Pediaditakis, Kristi L. Helke, Madeline S. Hall, Xiuxia Du, Susan Sumner, Sergey A. Krupenko
Published 2020-11-01

Knockout of Putative Tumor Suppressor Aldh1l1 in Mice Reprograms Metabolism to Accelerate Growth of Tumors in a Diethylnitrosamine (DEN) Model of Liver Carcinogenesis

by Natalia I. Krupenko, Jaspreet Sharma, Halle M. Fogle, Peter Pediaditakis, Kyle C. Strickland, Xiuxia Du, Kristi L. Helke, Susan Sumner, Sergey A. Krupenko
Published 2021-06-01

Meprin β metalloproteases associated with differential metabolite profiles in the plasma and urine of mice with type 1 diabetes and diabetic nephropathy

by Jessica Gooding, Lei Cao, Courtney Whitaker, Jean-Marie Mwiza, Mizpha Fernander, Faihaa Ahmed, Zach Acuff, Susan McRitchie, Susan Sumner, Elimelda Moige Ongeri
Published 2019-04-01

Metabolic Response of Triple-Negative Breast Cancer to Folate Restriction

by Michael F. Coleman, Ciara H. O’Flanagan, Alexander J. Pfeil, Xuewen Chen, Jane B. Pearce, Susan Sumner, Sergey A. Krupenko, Stephen D. Hursting
Published 2021-05-01

EDC IMPACT: Molecular effects of developmental FM 550 exposure in Wistar rat placenta and fetal forebrain

by Kylie D Rock, Brian Horman, Allison L Phillips, Susan L McRitchie, Scott Watson, Jocelin Deese-Spruill, Dereje Jima, Susan Sumner, Heather M Stapleton, Heather B Patisaul
Published 2018-02-01

A Microbiomic Analysis in African Americans with Colonic Lesions Reveals Streptococcus sp.VT162 as a Marker of Neoplastic Transformation

by Hassan Brim, Shibu Yooseph, Edward Lee, Zaki A. Sherif, Muneer Abbas, Adeyinka O. Laiyemo, Sudhir Varma, Manolito Torralba, Scot E. Dowd, Karen E. Nelson, Wimal Pathmasiri, Susan Sumner, Willem de Vos, Qiaoyi Liang, Jun Yu, Erwin Zoetendal, Hassan Ashktorab
Published 2017-11-01