Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival

by Sebastian Horn, Michelle A. Hughes, Ramon Schilling, Carsten Sticht, Tencho Tenev, Michaela Ploesser, Pascal Meier, Martin R. Sprick, Marion MacFarlane, Martin Leverkus
Published 2017-04-01

SUMO-mediated regulation of NLRP3 modulates inflammasome activity

by Rachael Barry, Sidonie Wicky John, Gianmaria Liccardi, Tencho Tenev, Isabel Jaco, Chih-Hong Chen, Justin Choi, Paulina Kasperkiewicz, Teresa Fernandes-Alnemri, Emad Alnemri, Marcin Drag, Yuan Chen, Pascal Meier
Published 2018-08-01

Hepatitis E virus genotypes and subgenotypes causing acute hepatitis, Bulgaria, 2013-2015.

by Roberto Bruni, Umbertina Villano, Michele Equestre, Paola Chionne, Elisabetta Madonna, Dilyana Trandeva-Bankova, Maria Peleva-Pishmisheva, Tencho Tenev, Eleonora Cella, Massimo Ciccozzi, Giulio Pisani, Elitsa Golkocheva-Markova, Anna Rita Ciccaglione
Published 2018-01-01

Prevalence of hepatitis C in the adult population of Bulgaria: a pilot study

by Ida Sperle, Stine Nielsen, Martyna Gassowski, Zlatina Naneva, Tanya Perchemlieva, Andrew Amato-Gauci, Matthias an der Heiden, Viviane Bremer, Elitsa Golkocheva-Markova, Kristiyan Hristov, Elena Kaneva, Yanita Simeonova, Tencho Tenev, Tonka Varleva, Erika Duffell, Ruth Zimmermann
Published 2020-07-01

RIPK1‐mediated immunogenic cell death promotes anti‐tumour immunity against soft‐tissue sarcoma

by Henry G Smith, Kunzah Jamal, Jasbani HS Dayal, Tencho Tenev, Joan Kyula‐Currie, Naomi Guppy, Patrycja Gazinska, Victoria Roulstone, Gianmaria Liccardi, Emma Davies, Ioannis Roxanis, Alan A Melcher, Andrew J Hayes, Gareth J Inman, Kevin J Harrington, Pascal Meier
Published 2020-06-01

The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles

by Mariam H. Orme, Gianmaria Liccardi, Nina Moderau, Rebecca Feltham, Sidonie Wicky-John, Tencho Tenev, Lior Aram, Rebecca Wilson, Katiuscia Bianchi, Otto Morris, Celia Monteiro Domingues, David Robertson, Meghana Tare, Alexander Wepf, David Williams, Andreas Bergmann, Matthias Gstaiger, Eli Arama, Paulo S. Ribeiro, Pascal Meier
Published 2016-03-01

Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1’s Cytotoxic Potential

by Rebecca Feltham, Kunzah Jamal, Tencho Tenev, Gianmaria Liccardi, Isabel Jaco, Celia Monteiro Domingues, Otto Morris, Sidonie Wicky John, Alessandro Annibaldi, Marcella Widya, Conor J. Kearney, Danielle Clancy, Paul R. Elliott, Timo Glatter, Qi Qiao, Andrew J. Thompson, Alexey Nesvizhskii, Alexander Schmidt, David Komander, Hao Wu, Seamus Martin, Pascal Meier
Published 2018-04-01

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

by Lesley-Ann Martin, Ricardo Ribas, Nikiana Simigdala, Eugene Schuster, Sunil Pancholi, Tencho Tenev, Pascal Gellert, Laki Buluwela, Alison Harrod, Allan Thornhill, Joanna Nikitorowicz-Buniak, Amandeep Bhamra, Marc-Olivier Turgeon, George Poulogiannis, Qiong Gao, Vera Martins, Margaret Hills, Isaac Garcia-Murillas, Charlotte Fribbens, Neill Patani, Zheqi Li, Matthew J. Sikora, Nicholas Turner, Wilbert Zwart, Steffi Oesterreich, Jason Carroll, Simak Ali, Mitch Dowsett
Published 2017-11-01

Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance

by Laura Ramos Garcia, Tencho Tenev, Richard Newman, Rachel O. Haich, Gianmaria Liccardi, Sidonie Wicky John, Alessandro Annibaldi, Lu Yu, Mercedes Pardo, Samuel N. Young, Cheree Fitzgibbon, Winnie Fernando, Naomi Guppy, Hyojin Kim, Lung-Yu Liang, Isabelle S. Lucet, Andrew Kueh, Ioannis Roxanis, Patrycja Gazinska, Martin Sims, Tomoko Smyth, George Ward, John Bertin, Allison M. Beal, Brad Geddes, Jyoti S. Choudhary, James M. Murphy, K. Aurelia Ball, Jason W. Upton, Pascal Meier
Published 2021-06-01