Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division

by Jennifer J Banerjee, Birgit L Aerne, Maxine V Holder, Simon Hauri, Matthias Gstaiger, Nicolas Tapon
Published 2017-06-01

The Protein Interaction Landscape of the Human CMGC Kinase Group

by Markku Varjosalo, Salla Keskitalo, Audrey Van Drogen, Helka Nurkkala, Anton Vichalkovski, Ruedi Aebersold, Matthias Gstaiger
Published 2013-04-01

Multi-layered proteomic analyses decode compositional and functional effects of cancer mutations on kinase complexes

by Martin Mehnert, Rodolfo Ciuffa, Fabian Frommelt, Federico Uliana, Audrey van Drogen, Kilian Ruminski, Matthias Gstaiger, Ruedi Aebersold
Published 2020-07-01

A High-Density Map for Navigating the Human Polycomb Complexome

by Simon Hauri, Federico Comoglio, Makiko Seimiya, Moritz Gerstung, Timo Glatter, Klaus Hansen, Ruedi Aebersold, Renato Paro, Matthias Gstaiger, Christian Beisel
Published 2016-10-01

Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data

by Alexander Schäfer, Enio Gjerga, Richard WD Welford, Imke Renz, Francois Lehembre, Peter MA Groenen, Julio Saez‐Rodriguez, Ruedi Aebersold, Matthias Gstaiger
Published 2019-08-01

Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy

by Javier Celis-Gutierrez, Peter Blattmann, Yunhao Zhai, Nicolas Jarmuzynski, Kilian Ruminski, Claude Grégoire, Youcef Ounoughene, Frédéric Fiore, Ruedi Aebersold, Romain Roncagalli, Matthias Gstaiger, Bernard Malissen
Published 2019-06-01

Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen

by Federico Uliana, Matej Vizovišek, Laura Acquasaliente, Rodolfo Ciuffa, Andrea Fossati, Fabian Frommelt, Sandra Goetze, Bernd Wollscheid, Matthias Gstaiger, Vincenzo De Filippis, Ulrich auf dem Keller, Ruedi Aebersold
Published 2021-03-01

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency

by Joana G Marques, Berkley E Gryder, Blaz Pavlovic, Yeonjoo Chung, Quy A Ngo, Fabian Frommelt, Matthias Gstaiger, Young Song, Katharina Benischke, Dominik Laubscher, Marco Wachtel, Javed Khan, Beat W Schäfer
Published 2020-08-01

ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail

by M. Teresa Bertran, Stéphane Mouilleron, Yanxiang Zhou, Rakhi Bajaj, Federico Uliana, Ganesan Senthil Kumar, Audrey van Drogen, Rebecca Lee, Jennifer J. Banerjee, Simon Hauri, Nicola O’Reilly, Matthias Gstaiger, Rebecca Page, Wolfgang Peti, Nicolas Tapon
Published 2019-02-01

The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles

by Mariam H. Orme, Gianmaria Liccardi, Nina Moderau, Rebecca Feltham, Sidonie Wicky-John, Tencho Tenev, Lior Aram, Rebecca Wilson, Katiuscia Bianchi, Otto Morris, Celia Monteiro Domingues, David Robertson, Meghana Tare, Alexander Wepf, David Williams, Andreas Bergmann, Matthias Gstaiger, Eli Arama, Paulo S. Ribeiro, Pascal Meier
Published 2016-03-01

Precise Temporal Profiling of Signaling Complexes in Primary Cells Using SWATH Mass Spectrometry

by Etienne Caron, Romain Roncagalli, Takeshi Hase, Witold E. Wolski, Meena Choi, Marisa G. Menoita, Stephane Durand, Antonio García-Blesa, Ivo Fierro-Monti, Tatjana Sajic, Moritz Heusel, Tobias Weiss, Marie Malissen, Ralph Schlapbach, Ben C. Collins, Samik Ghosh, Hiroaki Kitano, Ruedi Aebersold, Bernard Malissen, Matthias Gstaiger
Published 2017-03-01