Genetic connections between neurological disorders and cholesterol metabolism

by Ingemar Björkhem, Valerio Leoni, Steve Meaney
Published 2010-09-01

Levels of 7-oxocholesterol in cerebrospinal fluid are more than one thousand times lower than reported in multiple sclerosis

by Valerio Leoni, Dieter Lütjohann, Thomas Masterman
Published 2005-02-01

Old and New Beta-Lactamase Inhibitors: Molecular Structure, Mechanism of Action, and Clinical Use

by Davide Carcione, Claudia Siracusa, Adela Sulejmani, Valerio Leoni, Jari Intra
Published 2021-08-01

Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers

by Valerio Leoni, Thomas Masterman, Pria Patel, Steve Meaney, Ulf Diczfalusy, Ingemar Björkhem
Published 2003-04-01

Plasma 24S-hydroxycholesterol correlation with markers of Huntington disease progression

by Valerio Leoni, Jeffrey D. Long, James A. Mills, Stefano Di Donato, Jane S. Paulsen
Published 2013-07-01

Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington’s disease

by Marta Valenza, Valerio Leoni, Alessia Tarditi, Caterina Mariotti, Ingeman Björkhem, Stefano Di Donato, Elena Cattaneo
Published 2007-10-01

Evaluation of a rapid diagnostic test for detection of SARS-CoV-2 antigen in nasopharyngeal swabs

by Davide Carcione, Jari Intra, Daniela Riggio, Simona Sabella, Lorenza Rondelli, Simone Barbieri, Valerio Leoni, Maria Luisa Biondi
Published 2021-05-01

Purple corn extract induces long-lasting reprogramming and M2 phenotypic switch of adipose tissue macrophages in obese mice

by Federica Tomay, Alessandra Marinelli, Valerio Leoni, Claudio Caccia, Andrea Matros, Hans-Peter Mock, Chiara Tonelli, Katia Petroni
Published 2019-07-01

Immunotherapeutic Efficacy of Retargeted oHSVs Designed for Propagation in an Ad Hoc Cell Line

by Andrea Vannini, Valerio Leoni, Mara Sanapo, Tatiana Gianni, Giorgia Giordani, Valentina Gatta, Catia Barboni, Anna Zaghini, Gabriella Campadelli-Fiume
Published 2021-01-01

Genotype of Immunologically Hot or Cold Tumors Determines the Antitumor Immune Response and Efficacy by Fully Virulent Retargeted oHSV

by Tatiana Gianni, Valerio Leoni, Mara Sanapo, Federico Parenti, Daniela Bressanin, Catia Barboni, Anna Zaghini, Gabriella Campadelli-Fiume, Andrea Vannini
Published 2021-09-01

Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol

by Valeria Cagno, Andrea Civra, Daniela Rossin, Simone Calfapietra, Claudio Caccia, Valerio Leoni, Nicholas Dorma, Fiorella Biasi, Giuseppe Poli, David Lembo
Published 2017-08-01

Involvement of 27-Hydroxycholesterol in Mitotane Action on Adrenocortical Carcinoma

by Antonina Germano, Daniela Rossin, Valerio Leoni, Noemi Iaia, Laura Saba, Vittoria Basile, Soraya Puglisi, Claudio Caccia, Giuseppe Poli, Fiorella Biasi, Massimo Terzolo
Published 2020-04-01

Susceptibility of human placenta derived mesenchymal stromal/stem cells to human herpesviruses infection.

by Simone Avanzi, Valerio Leoni, Antonella Rotola, Francesco Alviano, Liliana Solimando, Giacomo Lanzoni, Laura Bonsi, Dario Di Luca, Cosetta Marchionni, Gualtiero Alvisi, Alessandro Ripalti
Published 2013-01-01

Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2

by Erica Staurenghi, Valentina Cerrato, Paola Gamba, Gabriella Testa, Serena Giannelli, Valerio Leoni, Claudio Caccia, Annalisa Buffo, Wendy Noble, Beatriz Gomez Perez-Nievas, Gabriella Leonarduzzi
Published 2021-02-01

A fully-virulent retargeted oncolytic HSV armed with IL-12 elicits local immunity and vaccine therapy towards distant tumors.

by Valerio Leoni, Andrea Vannini, Valentina Gatta, Julie Rambaldi, Mara Sanapo, Catia Barboni, Anna Zaghini, Patrizia Nanni, Pier-Luigi Lollini, Costanza Casiraghi, Gabriella Campadelli-Fiume
Published 2018-08-01

Octadecaneuropeptide (ODN) Induces N2a Cells Differentiation through a PKA/PLC/PKC/MEK/ERK-Dependent Pathway: Incidence on Peroxisome, Mitochondria, and Lipid Profiles

by Amira Namsi, Thomas Nury, Amira. S. Khan, Jérôme Leprince, David Vaudry, Claudio Caccia, Valerio Leoni, Atanas G. Atanasov, Marie-Christine Tonon, Olfa Masmoudi-Kouki, Gérard Lizard
Published 2019-09-01

Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice

by Mahalakshmi Shankaran, Eleonora Di Paolo, Valerio Leoni, Claudio Caccia, Costanza Ferrari Bardile, Hussein Mohammed, Stefano Di Donato, Seung Kwak, Deanna Marchionini, Scott Turner, Elena Cattaneo, Marta Valenza
Published 2017-02-01

The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients

by Alessandro Marcello, Andrea Civra, Rafaela Milan Bonotto, Lais Nascimento Alves, Sreejith Rajasekharan, Chiara Giacobone, Claudio Caccia, Roberta Cavalli, Marco Adami, Paolo Brambilla, David Lembo, Giuseppe Poli, Valerio Leoni
Published 2020-09-01

Biomarker report from the phase II lamotrigine trial in secondary progressive MS - neurofilament as a surrogate of disease progression.

by Sharmilee Gnanapavan, Donna Grant, Steve Morant, Julian Furby, Tom Hayton, Charlotte E Teunissen, Valerio Leoni, Monica Marta, Robert Brenner, Jacqueline Palace, David H Miller, Raj Kapoor, Gavin Giovannoni
Published 2013-01-01

RETRACTED ARTICLE: Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer

by Anthony Alioui, Julie Dufour, Valerio Leoni, Anke Loregger, Martina Moeton, Luigi Iuliano, Chiara Zerbinati, Amandine Septier, Pierre Val, Allan Fouache, Vincenzo Russo, David H. Volle, Jean-Marc A. Lobaccaro, Noam Zelcer, Silvère Baron
Published 2017-09-01