NF-κB Fans the Flames of Lung Carcinogenesis

by Wong, Kwok-Kin, Dranoff, Glenn, Jacks, Tyler E
Published 2014

A systems biology pipeline identifies regulatory networks for stem cell engineering

by Kinney, Melissa A., Vo, Linda T., Frame, Jenna M., Barragan, Jessica, Conway, Ashlee J., Li, Shuai, Wong, Kwok-Kin, Collins, James J., Cahan, Patrick, North, Trista E., Lauffenburger, Douglas A, Daley, George Q.
Published 2020

High MITF Expression Is Associated with Super-Enhancers and Suppressed by CDK7 Inhibition in Melanoma

by Eliades, Philip, Abraham, Brian J., Ji, Zhenyu, Christensen, Camilla L., Kwiatkowski, Nicholas, Kumar, Raj, Njauw, Ching Ni, Taylor, Michael, Miao, Benchun, Zhang, Tinghu, Wong, Kwok-Kin, Gray, Nathanael S., Tsao, Hensin, Young, Richard A., Miller, David M., III
Published 2019

CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer

by Chipumuro, Edmond, Marco, Eugenio, Christensen, Camilla L, Zhang, Tinghu, Hatheway, Clark M, Sharma, Bandana, Yeung, Caleb, Altabef, Abigail, Perez-Atayde, Antonio, Wong, Kwok-Kin, Yuan, Guo-Cheng, Gray, Nathanael S, George, Rani E, Kwiatkowski, Nick, Abraham, Brian Joseph, Young, Richard A.
Published 2017

BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells

by Debruyne, David N., Dries, Ruben, Sengupta, Satyaki, Seruggia, Davide, Gao, Yang, Sharma, Bandana, Huang, Hao, Moreau, Lisa, McLane, Michael, Day, Daniel Sindt, Marco, Eugenio, Chen, Ting, Gray, Nathanael S., Wong, Kwok-Kin, Orkin, Stuart H., Yuan, Guo-Cheng, Young, Richard A., George, Rani E.
Published 2020

Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR

by Liu, Qingsong, Xu, Chunxiao, Kirubakaran, Sivapriya, Zhang, Xin, Hur, Wooyoung, Kwiatkowski, Nicholas P., Wang, Jinhua, Westover, Kenneth D., Gao, Peng, Ercan, Dalia, Niepel, Mario, Thoreen, Carson C., Kang, Seong A., Patricelli, Matthew P., Wang, Yuchuan, Tupper, Tanya, Altabef, Abigail, Kawamura, Hidemasa, Held, Kathryn D., Chou, Danny M., Elledge, Stephen J., Janne, Pasi A., Wong, Kwok-Kin, Gray, Nathanael S., Sabatini, David, Liu, Yan
Published 2015

JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition

by McKenney, Anna Sophia, Somasundara, Amritha Varshini Hanasoge, Spitzer, Barbara, Intlekofer, Andrew M., Ahn, Jihae, Shank, Kaitlyn, Rapaport, Franck T., Patel, Minal A., Papalexi, Efthymia, Chiu, April, Freinkman, Elizaveta, Akbay, Esra A., Steadman, Mya, Nagaraja, Raj, Yen, Katharine, Teruya-Feldstein, Julie, Wong, Kwok-Kin, Rampal, Raajit, Levine, Ross L., Lau, Allison N., Shihadeh, Alan, Vander Heiden, Matthew G., Thompson, Craig B., Levine, Ross L
Published 2018

Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor

by Christensen, Camilla L, Carretero, Julian, Al-Shahrour, Fatima, Zhang, Tinghu, Chipumuro, Edmond, Herter-Sprie, Grit S, Akbay, Esra A, Altabef, Abigail, Zhang, Jianming, Shimamura, Takeshi, Capelletti, Marzia, Reibel, Jakob B, Cavanaugh, Jillian D, Gao, Peng, Liu, Yan, Michaelsen, Signe R, Poulsen, Hans S, Aref, Amir R, Barbie, David A, Bradner, James E, George, Rani E, Gray, Nathanael S, Wong, Kwok-Kin, Kwiatkowski, Nick, Abraham, Brian Joseph, Young, Richard A.
Published 2017

Suppression of Adaptive Responses to Targeted Cancer Therapy by Transcriptional Repression

by Rusan, Maria, Li, Kapsok, Li, Yvonne, Christensen, Camilla L., Abraham, Brian J., Kwiatkowski, Nicholas, Buczkowski, Kevin A., Bockorny, Bruno, Chen, Ting, Li, Shuai, Rhee, Kevin, Zhang, Haikuo, Chen, Wankun, Terai, Hideki, Tavares, Tiffany, Leggett, Alan L., Li, Tianxia, Wang, Yichen, Zhang, Tinghu, Kim, Tae-Jung, Hong, Sook-Hee, Poudel-Neupane, Neermala, Silkes, Michael, Mudianto, Tenny, Tan, Li, Shimamura, Takeshi, Meyerson, Matthew, Bass, Adam J., Watanabe, Hideo, Gray, Nathanael S., Young, Richard A., Wong, Kwok-Kin, Hammerman, Peter S.
Published 2019

Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop

by Bedognetti, Davide, Ceccarelli, Michele, Galluzzi, Lorenzo, Lu, Rongze, Palucka, Karolina, Samayoa, Josue, Spranger-Zimmermann, Stefani, Warren, Sarah, Wong, Kwok-Kin, Ziv, Elad, Chowell, Diego, Coussens, Lisa M., De Carvalho, Daniel D., DeNardo, David G., Galon, Jérôme, Kaufman, Howard L., Kirchhoff, Tomas, Lotze, Michael T., Luke, Jason J., Minn, Andy J., Politi, Katerina, Shultz, Leonard D., Simon, Richard, Thórsson, Vésteinn, Weidhaas, Joanne B., Ascierto, Maria Libera, Ascierto, Paolo Antonio, Barnes, James M., Barsan, Valentin, Bommareddy, Praveen K., Bot, Adrian, Church, Sarah E., Ciliberto, Gennaro, De Maria, Andrea, Draganov, Dobrin, Ho, Winson S., McGee, Heather M., Monette, Anne, Murphy, Joseph F., Nisticò, Paola, Park, Wungki, Patel, Maulik, Quigley, Michael, Radvanyi, Laszlo, Raftopoulos, Harry, Rudqvist, Nils-Petter, Snyder, Alexandra, Sweis, Randy F., Valpione, Sara, Zappasodi, Roberta, Butterfield, Lisa H., Disis, Mary L., Fox, Bernard A., Cesano, Alessandra, Marincola, Francesco M.
Published 2020