Quantitative Analysis of Repertoire-Scale Immunoglobulin Properties in Vaccine-Induced B-Cell Responses

Quantitative Analysis of Repertoire-Scale Immunoglobulin Properties in Vaccine-Induced B-Cell Responses

Recent advances in the next-generation sequencing of B-cell receptors (BCRs) enable the characterization of humoral responses at a repertoire-wide scale and provide the capability for identifying unique features of immune repertoires in response to disease, vaccination, or infection. Immunosequencin...

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Bibliographic Details
Main Authors: Ilja V. Khavrutskii, Sidhartha Chaudhury, Sabrina M. Stronsky, Donald W. Lee, Jacqueline G. Benko, Anders Wallqvist, Sina Bavari, Christopher L. Cooper
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Immunology
Subjects:
repertoire properties
immunosequencing
clonotype
Ebola
statistical analysis
B cell
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00910/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00910/full

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