Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing

Chronic wounds: Gel encourages healing and reduces scarring A promising, recently developed topical treatment prevents detrimental enzyme activity in burn wounds, accelerates healing and reduces scarring. Chronic wounds that do not heal fully and require ongoing medical attention are common in the e...

Full description

Bibliographic Details
Main Authors: Yue Shen, Matthew R. Zeglinski, Christopher T. Turner, Sheetal A. Raithatha, Zhenguo Wu, Valerio Russo, Cameron Oram, Sho Hiroyasu, Layla Nabai, Hongyan Zhao, Tatjana Bozin, Kathryn Westendorf, Irina Kopko, Rachel Huang, Steve Arns, Jason Tan, Haishan Zeng, Anthony Boey, Richard Liggins, James Jaquith, Dale R. Cameron, Anthony Papp, David J. Granville
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0095-0