Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection

Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection

Background: SARS-CoV-2 serology is used to identify prior infection at individual and at population level. Extended longitudinal studies with multi-timepoint sampling to evaluate dynamic changes in antibody levels are required to identify the time horizon in which these applications of serology are...

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Bibliographic Details
Main Authors: Charlotte Manisty, Thomas Alexander Treibel, Melanie Jensen, Amanda Semper, George Joy, Rishi K Gupta, Teresa Cutino-Moguel, Mervyn Andiapen, Jessica Jones, Stephen Taylor, Ashley Otter, Corrina Pade, Joseph Gibbons, Jason Lee, Joanna Bacon, Steve Thomas, Chris Moon, Meleri Jones, Dylan Williams, Jonathan Lambourne, Marianna Fontana, Daniel M Altmann, Rosemary Boyton, Mala Maini, Aine McKnight, Benjamin Chain, Mahdad Noursadeghi, James C Moon
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:EBioMedicine
Subjects:
SARS-CoV-2, Serology, Mathematical modelling, Sero-reversion
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421000529

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http://www.sciencedirect.com/science/article/pii/S2352396421000529

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